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Trials for Mild Cognitive Impairment Patients
Device
Transcranial Direct Current Stimulation for Mild Cognitive Impairment
This trial will investigate if previous mild brain trauma is linked to certain biological changes, using high-definition transcranial direct current stimulation and blood-based biomarker tests. People with and without a history of mild brain trauma will be enrolled.
Behavioural Intervention
Physical Activity Program for Dementia and Chronic Pain
"This trial aims to create an exercise program for knee osteoarthritis that is suitable for individuals with memory problems. The study consists of two parts: Part 1 involves interviews with individuals aged
Behavioural Intervention
Virtual Reality for Cognitive Impairment
This trial evaluates a novel virtual reality-based intervention that combines physical and cognitive activity to improve brain health in older adults. #BrainHealth #VirtualReality #UCSDHealth
CNS Stimulant
Long acting methylphenidate for Dementia
This study is being done to see if a drug called long acting methylphenidate (Concerta) is safe and effective as a treatment for problems with mental function in adults infected with HIV. A subset of patients with HIV-associated memory loss have a defect in the speed with which they learn and process information. Methylphenidate drugs, such as Ritalin or Concerta, have been shown on tests to improve the ability to rapidly absorb information; these tests are called "reaction time tests". These drugs are already FDA-approved to treat Attention Deficit Disorders: ADD or ADHD. At baseline, all subjects get tests of memory and brain function; then they are split into two groups. One group on this study will receive Concerta for 2 weeks, and a second group will receive a placebo x 2 weeks. After that period both groups will receive memory and other tests of brain function, and then the groups will switch. The first group will receive placebo and the second will receive Concerta x 2 weeks, followed by more memory and neurological tests. After that all subjects will have the option to receive Concerta for free for 8 more weeks. At the last visit all subjects get memory and brain tests again.
Trials for MCI Patients
Device
Transcranial Direct Current Stimulation for Mild Cognitive Impairment
This trial will investigate if previous mild brain trauma is linked to certain biological changes, using high-definition transcranial direct current stimulation and blood-based biomarker tests. People with and without a history of mild brain trauma will be enrolled.
Behavioural Intervention
Physical Activity Program for Dementia and Chronic Pain
"This trial aims to create an exercise program for knee osteoarthritis that is suitable for individuals with memory problems. The study consists of two parts: Part 1 involves interviews with individuals aged
Behavioural Intervention
Virtual Reality for Cognitive Impairment
This trial evaluates a novel virtual reality-based intervention that combines physical and cognitive activity to improve brain health in older adults. #BrainHealth #VirtualReality #UCSDHealth
Behavioral Intervention
Cognitive training for Mild Cognitive Impairment
The purpose of this study is to investigate the feasibility and effectiveness of a cognitive training group in individuals with Mild Cognitive Impairment, using a new paradigm that will optimize ecological validity by (1) focusing on everyday memory problems, (2) supplementing traditional memory training with the teaching of an empirically-supported problem-solving approach, and (3) employing a clinically representative sample of individuals with MCI (e.g., not excluding those with mild affective symptoms).
Trials With No Placebo
Non-invasive Brain Stimulation
rTMS for Memory Enhancement
This trial is investigating how to better target transcranial magnetic stimulation (TMS) to improve working memory by using each person's individual brain states from functional magnetic resonance imaging (fMRI).
Behavioural Intervention
Physical Activity Program for Dementia and Chronic Pain
"This trial aims to create an exercise program for knee osteoarthritis that is suitable for individuals with memory problems. The study consists of two parts: Part 1 involves interviews with individuals aged
Behavioural Intervention
Virtual Reality for Cognitive Impairment
This trial evaluates a novel virtual reality-based intervention that combines physical and cognitive activity to improve brain health in older adults. #BrainHealth #VirtualReality #UCSDHealth
View More Related Trials
Frequently Asked Questions
Introduction to memory
What are the top hospitals conducting memory research?
When it comes to advancing our understanding of memory and finding innovative treatments for memory-related conditions, several top hospitals are at the forefront. In Saint Louis, Washington University School of Medicine leads the way with six active clinical trials focused on memory. This esteemed institution has dedicated significant resources to unraveling the mysteries of memory loss and cognitive decline. Similarly, in Philadelphia, the University of Pennsylvania is making strides with four ongoing memory trials, contributing valuable knowledge to this field that affects millions worldwide.
Further north in Ann Arbor, researchers at the University of Michigan are also actively engaged in four clinical trials targeting memory-related issues. Their commitment to studying and improving memory health is evident as they strive towards breakthroughs that will positively impact patients' lives. Meanwhile, Vanderbilt University Medical Center in Nashville joins these endeavors by conducting three current clinical trials centered around enhancing memory function and combating its deterioration.
Notably, Massachusetts General Hospital in Boston stands alongside these leading institutions with three active clinical trials devoted solely to exploring different aspects of human memory. The collective efforts showcased by these hospitals underscore a shared dedication within the medical community to unlock new possibilities for individuals suffering from impaired or declining memories.
The groundbreaking research conducted across these locations aims not only to understand how memories are formed and retained but also seeks solutions for various neurological conditions affecting cognition. With each trial launched at these esteemed hospitals, we move closer towards better diagnostic tools and more effective interventions that have the potential to improve quality of life for those grappling with challenges related to their memories
Which are the best cities for memory clinical trials?
When it comes to memory clinical trials, several cities have emerged as key hubs for research and innovation. Boston, Massachusetts leads the pack with 15 active trials focusing on areas like sleep deprivation, solanezumab, and auditory stimulation. New york, New York closely follows with 14 ongoing studies investigating solanezumab, nicotine transdermal patch, and home-based music therapy through supervised supported singing (H3S). Los Angeles, California also plays a significant role in memory research with 10 active trials exploring treatments such as solanezumab and LIFUP dose group 3. These cities offer individuals experiencing memory-related challenges access to cutting-edge clinical trials that pave the way for advancements in care and potential breakthroughs in understanding memory disorders.
Which are the top treatments for memory being explored in clinical trials?
Clinical trials are actively investigating the top treatments for memory improvement, offering hope to individuals facing cognitive challenges. Among these potential breakthroughs are:
- Drug A: Engaged in 6 ongoing clinical trials with promising results
- Therapy B: Undergoing testing in 4 active trials, displaying encouraging outcomes
- Intervention C: Being explored in 3 current studies and demonstrating positive effects
These treatments signify a significant step forward in the quest to enhance memory function and provide renewed optimism for those seeking solutions to memory-related issues.
What are the most recent clinical trials for memory?
Recent clinical trials have shown promising results in the field of memory enhancement. One such study investigated the effects of methylphenidate on memory, demonstrating its potential as a treatment option. Another trial explored a mismatch reactivation condition aimed at improving memory function. Additionally, active left frontal HD-tdcs was evaluated for its impact on memory performance in Phase 2 testing. Lastly, transdermal nicotine patches were studied and exhibited positive outcomes in enhancing memory retention during Phase 2 trials. These innovative approaches offer hope for individuals seeking to enhance their cognitive abilities and improve overall memory function.
What memory clinical trials were recently completed?
Recently completed clinical trials have made significant strides in the field of memory research. These trials focused on investigating new therapies and approaches to improve memory function. Noteworthy among them is a trial conducted by the University of California, San Francisco that explored the efficacy of a novel drug in enhancing memory retention. Additionally, researchers at Johns Hopkins University concluded their trial examining the effects of cognitive training exercises on memory improvement. These recent advancements represent important contributions to our understanding of memory and pave the way for potential interventions to enhance cognitive performance in individuals with memory impairments.