Lung Cancer Clinical Trials 2022

Lung Cancer studies recruiting patients for novel treatments. Filter by phase, distance, and inclusion criteria to find your perfect lung cancer clinical trial in 2022.

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This will be a prospective, (NSR), single-center feasibility study of the Olympus VE2 NIR Imaging System to assess perfusion using NIR during minimally invasive esophagectomy and pulmonary segmentectomy. The aims of the study are: 1. To utilize NIR intraoperative imaging with the Olympus …

nCLE aided RANB biospy

This study is designed to evaluate the safety and feasibility of real-time needle-based confocal laser endomicroscopy (nCLE) in improving diagnostic accuracy of robotic-assisted bronchoscopy (RANB) biopsy performed with the Monarch® Endoscopy Platform in patients with peripheral pulmonary …

This study is evaluating whether a drug called sitravatinib can help treat lung cancer.

This study is evaluating whether a drug may be effective in treating cancer.

This study is evaluating whether a surgery which reduces blood flow in a stomach artery leads to significant weightloss.

Radiation with Concurrent Chemotherapy

This study is evaluating whether a combination of chemotherapy and radiation therapy is better than chemotherapy alone.

This is a Phase 1b, open-label, multi-center, dose-escalation and dose-expansion study designed to evaluate the safety, pharmacokinetics (PK), and preliminary antitumor activity of furmonertinib in patients with advanced or metastatic NSCLC with activating EGFR or HER2 mutations, including…

Transbronchial Microwave Ablation

This is a prospective, multicenter, single-arm study on transbronchial microwave ablation using the NEUWAVE FLEX Microwave Ablation System and Accessories on oligometastatic tumors in the peripheral lung, guided by the Auris MONARCH Platform for visualization and access while using cone be…

Pembrolizumab/Vibostolimab

This study is evaluating whether a drug may help treat lung cancer.

EHR-integrated Shared Decision Making Tool and Clinical Decision Support for Lung Cancer Screening

This study is evaluating whether a new computer program can help doctors and patients make better decisions about whether to have a low-dose CT scan for lung cancer.

Survey-based Patient/Clinician Jumpstart

This study is evaluating whether a survey-based patient/clinician Jumpstart guide improves quality of care for patients with chronic illness.

Proactive Telephone Counseling from VA Quitline

This study is evaluating whether providing smokers with support to quit smoking will help them quit.

This study is evaluating whether a drug called CK-101 can be used to treat lung cancer.

Background: EP0057 consists of a sugar molecule cyclodextrin linked to a chemotherapy drug called camptothecin. The combined molecule or "nanoparticle drug conjugate" travels through the blood. Once inside cancer cells, the chemotherapy drug is released from the molecule. Olaparib is a dru…

This study is evaluating whether a surgery which reduces blood flow in a stomach artery leads to significant weightloss.

This study is evaluating whether a screening program for lung cancer can be implemented in Alberta.

The purpose of this study is to assess the efficacy and safety of pembrolizumab in combination with concurrent chemoradiation therapy followed by either pembrolizumab with olaparib placebo (Arm 1) or with olaparib (Arm 2) compared to concurrent chemoradiation therapy followed by durvalumab…

Vandetanib

Hilton Head Island, SC

Hilton Head Island, SC

18+

All Sexes

This study is evaluating whether a drug that inhibits both VEGFR and EGFR signalling is more effective than a drug that only inhibits EGFR signalling.

Near Infrared Imaging

The primary purpose of this study is to determine if we can identify the first lymph node that drains from the tumor, and thus would be the most likely site for metastatic disease, and remove it for analysis to improve the ability to detect tumor in this node and to remove this additional …

This study is evaluating whether a combination of radiation and chemotherapy is better than radiation alone for treating non-small cell lung cancer.

This study is evaluating whether a combination of cediranib maleate and pemetrexed disodium and cisplatin is safe and effective in treating patients with malignant pleural mesothelioma.

This study is evaluating whether there is a relationship between the genes that encode for topoisomerase II and CYP4503A4 and the effectiveness of chemotherapy in patients with small cell lung cancer.

This study is evaluating whether a drug can improve the effectiveness of chemotherapy in people with lung cancer.

This study is evaluating whether chemotherapy and radiation therapy work better when given with or without panitumumab in treating patients with non-small cell lung cancer.

This study is evaluating whether chemotherapy with or without bevacizumab and/or cetuximab is more effective in treating patients with stage IV or non-small cell lung cancer that has returned after a period of improvement.

This study is evaluating whether cryotherapy can be used to treat lung cancer.

High Radiation Dose Therapy

This study is evaluating whether different radiation therapy regimens work better than others when given together with chemotherapy.

Irinotecan Hydrochloride

This study is evaluating the side effects and best dose of veliparib when given together with irinotecan hydrochloride in treating patients with cancer that has spread to other parts of the body or that cannot be removed by surgery.

This study is evaluating whether high-dose radiation therapy is more effective than standard-dose radiation therapy when given together with chemotherapy with or without cetuximab in treating patients with non-small cell lung cancer.

stereotactic ablative radiotherapy (SABR)

This study is evaluating whether a drug called pentoxifylline and a radiation therapy called stereotactic ablative body radiotherapy (SABR) can be used to treat lung cancer.

This study is evaluating whether a combination of drugs can be used to treat lung cancer.

This study is evaluating whether a drug called tremelimumab can help people with mesothelioma.

This study is evaluating whether a new drug called LDK378 is more effective than chemotherapy in treating lung cancer.

This study is evaluating whether a drug called TAS-102 can help treat people with advanced non-small cell lung cancer.

This study is evaluating whether a combination of a drug called selumetinib and two different doses of docetaxel can improve the survival of people with advanced lung cancer.

This study is evaluating whether a combination of auranofin and sirolimus is safe and effective in treating patients with lung cancer.

This study is evaluating whether a higher dose of radiation therapy is better than a lower dose of radiation therapy for treating patients with locally advanced non-small cell lung cancer.

The purpose of this phase II study is to find out what effects cabozantinib (XL184) has, good and/or bad, in patients whose tumors one of the following gene changes RET, ROS1, or NTRK fusion, or increased MET or AXL activity. A phase II study looks at how effective a medication is at trea…

Pharmacological Study

This study is evaluating the side effects and best dose of romidepsin in treating patients with lymphoma, chronic lymphocytic leukemia, or solid tumors with liver dysfunction.

Background: The NCI Surgery Branch has developed an experimental therapy that involves taking white blood cells from patients' tumors, growing them in the laboratory in large numbers, and then giving the cells back to the patient. These cells are called Tumor Infiltrating Lymphocytes, or …

This study is evaluating whether a drug called MEDI4736 can help people with lung cancer.

This study is evaluating whether a drug called durvalumab can help treat lung cancer.

This study is evaluating whether a new drug called alectinib is better than crizotinib for treating people with advanced non-small cell lung cancer.

This study is evaluating whether a drug called palbociclib can be used to treat lung cancer.

This study is evaluating whether a type of radiation therapy may be more effective than another type of radiation therapy in treating non-small cell lung cancer.

Phase 1 and 2 trial to study the safety, pharmacokinetics, pharmacodynamics, patient reported outcomes and efficacy of PF-06463922 in ALK + advanced non-small cell lung cancer patients and ROS1+ advanced non small cell lung cancer patients .

This study is evaluating whether a drug called selumetinib can improve the survival of people with lung cancer.

This study is evaluating whether a drug may help treat depression.

Stereotactic Body Radiation Therapy (SBRT)

This study is evaluating whether a set of biomarkers and functional MRI images can predict response to stereotactic body radiation therapy (SBRT) for non-small cell lung cancer (NSCLC).

This study is evaluating whether a new drug called MEDI4736 is better than no further treatment after surgery for lung cancer.

hypofractionated radiation therapy

This study is evaluating whether a boost of radiation to the primary tumor before standard chemotherapy and radiation therapy works in treating patients with stage II or III non-small cell lung cancer that cannot be removed by surgery.

This study is evaluating whether a combination of two immunotherapy drugs may help treat lung cancer.

This study is evaluating whether a drug called BMS-986012 can be used to treat people with relapsed or refractory small cell lung cancer.

This study is evaluating whether inhaled iloprost is safe and effective in preventing lung cancer in former smokers.

This study is evaluating whether a drug called crizotinib may help treat patients with non-small cell lung cancer.

This study is evaluating whether chemotherapy and radiation therapy works better when given with or without metformin hydrochloride.

This study is evaluating whether itraconazole can increase the exposure of AZD9291 in patients with EGFRm+ NSCLC.

This study is evaluating whether a drug called abemaciclib is safe and effective in people with lung cancer.

This study is evaluating whether a new drug called osimertinib is better than standard chemotherapy for people with lung cancer.

This study is evaluating whether high doses of vitamin C may help treat lung cancer.

This study is evaluating whether a drug called pembrolizumab can help treat people with malignant mesothelioma.

This study is evaluating whether a combination of chemotherapy and immunotherapy is safe and effective for people with advanced non-small cell lung cancer.

Subcutaneous (SC) SEA-CD40

This study is evaluating whether SEA-CD40 is safe and effective when given alone, in combination with pembrolizumab, and in combination with pembrolizumab, gemcitabine, and nab-paclitaxel

MEDI4736 (durvalumab)

This study is evaluating whether a drug called durvalumab can improve the survival of people with lung cancer.

This study is evaluating whether a drug combination can be safely given to people with lung cancer.

This study is evaluating whether a drug called pembrolizumab (MK-3475) can help people with lung cancer who have already had treatment for their disease.

This study is evaluating whether a drug called nintedanib can improve outcomes for people with lung cancer.

This study is evaluating whether a new drug called AZD9291 is more effective than a standard of care drug called erlotinib in treating lung cancer.

This study is evaluating whether a combination of nab-paclitaxel and CC-486 is safe and effective for people with advanced non-small cell lung cancer.

This study is evaluating whether atezolizumab is more effective than best supportive care in people with non-small cell lung cancer.

This study is evaluating whether a combination of temozolomide and olaparib is a possible treatment for Small Cell Lung Cancer.

This study is evaluating whether a vaccine combined with a checkpoint inhibitor is safe for patients with non-small cell lung cancer.

This study is evaluating whether pemetrexed disodium is safe and effective in treating patients with stage IV non-small cell lung cancer and a performance status of 3.

This is a study for patients with previously-treated advanced non-small cell lung cancer (NSCLC). The study will evaluate the safety of adding an investigational drug, MK-3475 to standard treatment with gemcitabine. The study will also try to identify the best dose of MK-3475 to give in co…

This study is evaluating whether a drug that blocks a protein called c-MET can help treat lung cancer.

This study is evaluating whether a drug called ramucirumab can improve the survival of people with lung cancer.

This study is evaluating whether a combination of chemotherapy and immunotherapy may be more effective than chemotherapy or immunotherapy alone.

Anti-PD-L1 Monoclonal Antibody MPDL3280A

This study is evaluating whether a combination of anti-PD-L1 monoclonal antibody MPDL3280A and stereotactic ablative radiotherapy is better than either treatment alone.

This study is evaluating whether a combination of a drug and a vaccine is better than the vaccine alone.

This study is evaluating whether methoxyamine can be safely given together with cisplatin and pemetrexed disodium to treat patients with solid tumors or mesothelioma that have spread to other places in the body and usually cannot be cured

This study is evaluating whether a drug called MDPL3280A can be safely added to standard chemotherapy and radiation for lung cancer.

This study is evaluating whether a drug combination is safe and tolerable for people with advanced and unresectable non-small cell lung cancer.

This study is evaluating whether two drugs may help treat lung cancer.

AZD1775