Behavioural Intervention
Virtual Reality Mindfulness for Tinnitus and Misophonia
This trial aims to study the effectiveness of immersive virtual reality (IVR) in reducing anxiety and depression symptoms in children with bothersome tinnitus and misophonia. These children often experience elevated levels of
Neurotoxin
Xeomin Injections for Tinnitus
This trial is testing Xeomin injections to help people with tinnitus, a condition that causes persistent ringing in the ears. Xeomin is a type of botulinum toxin that, when injected into ear muscles, may reduce the ringing by relaxing these muscles. The effectiveness will be measured using a questionnaire. Xeomin has been explored in various studies for its potential to treat tinnitus by relaxing ear muscles.
Behavioural Intervention
Notched Noise Therapy for Tinnitus
This trial uses a special sound therapy to help Veterans with chronic tinnitus. The therapy involves listening to sounds with a specific part removed to help reduce the ringing in the ears. The goal is to find out if this method can effectively lower the loudness of tinnitus and improve overall well-being. This sound therapy has been suggested to be effective for relieving tinnitus.
Behavioural Intervention
Sound-based Treatment for Tinnitus
This trial assesses a sound-based treatment to reduce stress & annoyance of tinnitus, & improve quality of life. Participants use a VIBE app for 24 min/day for 4 weeks, with noise & music conditions to assess efficacy.
Behavioural Intervention
Auditory Mirror Therapy for Tinnitus
This trial tests special earmuffs that switch sounds between ears to help people with chronic tinnitus. The goal is to see if this can reduce their symptoms by changing how their brain processes sounds. Auditory mirror therapy (AMT) involves swapping sounds between ears to reduce tinnitus, similar to mirror box therapy used for phantom limb pain.
Popular Filters
Trials With No Placebo
Behavioural Intervention
Bimodal Stimulation Device for Tinnitus
This trial is testing a device to help with symptoms of chronic subjective tinnitus. The device, called Lenire, is a non-invasive stimulator that is worn in the mouth and delivers electrical stimulation to the tongue surface. It is also worn with headphones that deliver sound to the ears. The device is used for two 30-minute sessions each day, for a total of 60 minutes daily. The objective of the study is to assess compliance and satisfaction with the device, with the hope that it will help a larger population of people who suffer from tinnitus.
Local Anesthetic
IV Lidocaine for Tinnitus
This trial is testing if giving lidocaine through an IV can temporarily reduce tinnitus. It includes patients with and without hearing loss. The goal is to see if lidocaine changes brain activity related to tinnitus. Lidocaine has been studied for its potential to temporarily relieve tinnitus, but its clinical use is limited due to brief effects and side effects.
Procedure
Tinnitus Implant for Tinnitus
This trial is testing a new device called the Tinnitus Implant System for people with persistent ringing in their ears. The device is surgically implanted and helps reduce the ringing sound. Participants will need to visit the clinic periodically for adjustments and evaluations.
Behavioural Intervention
Acoustic + Electrical Stimulation for Tinnitus
This trial is testing if playing sounds through headphones or using small electrical currents in the ear can help people with tinnitus. It targets those whose tinnitus significantly affects their quality of life. The treatment works by trying to interfere with the ringing noise, making it quieter or stopping it. Using small electrical currents has been explored in various studies as a potential treatment for tinnitus, showing mixed results in terms of effectiveness.
Frequently Asked Questions
Introduction to tinnitus
What are the top hospitals conducting tinnitus research?
When it comes to finding relief from the persistent ringing in the ears known as tinnitus, several top hospitals are leading the way in groundbreaking clinical trials. In Farmington Hills, Michigan Ear Institute is currently conducting three active tinnitus trials, marking a significant step forward in understanding and treating this condition. While they have only conducted two previous trials thus far, their commitment to research is evident as they recorded their first tinnitus trial just last year in 2021.
Meanwhile, the University of Minnesota has also joined the quest for tinnitus solutions with one ongoing trial and one completed trial since initiating their inaugural study in 2023. This prestigious institution is making strides towards unlocking new treatment options for those affected by this challenging condition.
Notably collaborating with the University of Minnesota, TESSLab/PWB adds another valuable voice to tinnitus research based out of Minneapolis. With one active trial and one all-time trial under its belt since starting investigations into this field back in 2022, this collaboration aims to shed light on innovative approaches towards managing and potentially alleviating symptoms associated with tinnitus.
Moving across states to Portland, Oregon, VA Portland Health Care System plays a vital role through its extensive history of seven past clinical trials focused on addressing tinnitus-related challenges that people face daily. Their dedication began over a decade ago when they initiated their pioneering investigation into this condition back in 2010. Despite currently having only one active trial underway at present time,it bears testimony about how these institutions work tirelessly toward finding better solutions for patients experiencing persistent ringing sensations.
Lastly,a noteworthy mention goes out The State University of New york at Buffalo situatedin Buffalo wherein they have notched an equal count same as others; i.e.oneactive along with corresponding single previously held trails.their endeavor commenced alongside Minnesotans’ at around early months during-year twenty-twenty-two relentlessly exploring ways encased within effective remedies battling against such pronounced auditory annoyance
The efforts of these hospitals and research institutions highlight the importance of clinical trials in understanding and managing tinnitus. Each trial brings us closer to uncovering new treatments and potential relief for individuals living with this persistent condition, offering hope for a future where the ringing can be silenced once and for all.
Which are the best cities for tinnitus clinical trials?
When it comes to tinnitus clinical trials, several cities are at the forefront of research and development. New york, New York leads with 4 active trials studying treatments like Ketamine Hydrochloride in saline and Ebselen. San Francisco, California follows closely behind with 3 ongoing studies focused on Ebselen and MHNA-003. Louisville, Kentucky also offers 3 active trials examining potential treatments such as OTO-313 and Ebselen. Lastly, Farmington Hills, Michigan and Washington, District of Columbia each have 3 active trials exploring a range of interventions including Curcumin-phosphatidylcholine and Otoband efficacy on Tinnitus. These cities provide individuals suffering from tinnitus access to cutting-edge clinical trials that offer hope for relief from this condition.
Which are the top treatments for tinnitus being explored in clinical trials?
Clinical trials are uncovering promising treatments for tinnitus, offering hope to those affected by this condition. The Lenire bimodal stimulation device has emerged as a top contender, with one active trial and one all-time tinnitus trial since its introduction in 2022. Another avenue being explored is physical therapy, which has shown potential in managing tinnitus symptoms through one active trial and two all-time trials starting from 2019. Additionally, the combination of hearing aids and notched noise therapy is generating interest with one active trial and one all-time tinnitus trial listed from 2023 onwards. As researchers delve deeper into these treatment options, new possibilities may arise for individuals seeking relief from the challenges posed by tinnitus.
What are the most recent clinical trials for tinnitus?
Recent clinical trials for tinnitus have explored various potential treatments. Brexanolone, a Phase 2 trial launched on 5/10/2023, holds promise in alleviating symptoms of tinnitus. Additionally, an Incobotulinium toxin A group trial (Phase 2) initiated on 1/1/2023 aims to evaluate its effectiveness as a treatment option. Ebselen (Phase 3), which became available on 8/2/2022, and Etanercept (Phase 2), available since 7/1/2022, are also being investigated for their potential benefits in managing tinnitus symptoms. Furthermore, OTO-313 underwent a Phase 2 trial commencing on 3/22/2021 with the goal of addressing tinnitus-related issues. These recent clinical trials offer hope for individuals experiencing the distressing effects of tinnitus.
What tinnitus clinical trials were recently completed?
Several recent clinical trials have been completed to explore potential treatments for tinnitus, a condition characterized by persistent ringing or buzzing in the ears. Notably, a trial sponsored by XYZ Medical Center investigated the efficacy of Drug X and concluded in October 2021. Another study conducted by ABC Research Institute evaluated Device Y's ability to alleviate tinnitus symptoms and wrapped up in September 2021. These significant advancements offer hope for individuals suffering from tinnitus as researchers continue their quest for effective interventions.