Head And Neck Squamous Cell Carcinoma Clinical Trials
Here are the 6 most popular medical studies for head and neck squamous cell carcinoma
Apoptosis Inhibitor
Xevinapant + Radiation and Chemotherapy for Oral Squamous Cell Carcinoma
This trial will test a new drug (xevinapant) combined with chemotherapy and radiation to fight head and neck cancer. Participants will get up to 4 doses to determine the safest dose, then a larger group will try that dose.
HC-7366 for Solid Tumors
This trial is testing a new cancer drug to see what the maximum tolerated dose is, what the recommended Phase 2 dose is, and to evaluate its safety and how well it is tolerated when taken orally once a day. The trial will enroll 36 subjects with advanced solid tumors, with up to 15 additional subjects in the expansion phase. The study will be conducted in the United States at 3-5 sites.
Popular filter options for head and neck squamous cell carcinoma trials
Squamous Cell Carcinoma Clinical Trials
View 57 Squamous Cell Carcinoma medical studies.
Monoclonal Antibodies
Imatinib + Cetuximab for Oral Squamous Cell Carcinoma
This trial tests whether a protein in cancer cells can predict how head and neck tumors respond to a combination of two treatments. Participants will be monitored for 13-16 months to assess the effectiveness.
SCC Clinical Trials
View 54 SCC medical studies.
Monoclonal Antibodies
Imatinib + Cetuximab for Oral Squamous Cell Carcinoma
This trial tests whether a protein in cancer cells can predict how head and neck tumors respond to a combination of two treatments. Participants will be monitored for 13-16 months to assess the effectiveness.
PD-L1 Positive Clinical Trials
View 10 PD-L1 positive medical studies.
Nanoparticle
NBTXR3 + Anti-PD-1 therapy for Advanced Cancers
This trial is testing a new cancer treatment that involves injecting a drug directly into tumors and combining it with anti-PD-1 therapy. The goal is to see if this is a safe and effective treatment for cancer.
Virus Therapy
CMP-001 + Pembrolizumab for Squamous Cell Carcinoma
This trial is testing a new combination treatment for head and neck squamous cell carcinoma that consists of an intratumoral injection of CMP-001 followed by intravenous pembrolizumab. The goal is to see if this new treatment is more effective than pembrolizumab alone, and if it is well tolerated by participants.
Alkaline Phosphatase Positive Clinical Trials
View 9 alkaline phosphatase positive medical studies.
Small Molecule Inhibitor
NT219 +1 More for Colorectal Cancer
This trial is testing a new drug, NT219, to see if it is safe and effective against solid tumors. The trial will have two parts, first testing different doses of NT219 to see what is safe, then testing NT219 with another drug, ERBITUX, to see if it is more effective than ERBITUX alone.
Alkylating agents
Chemotherapy + Bevacizumab for Head and Neck Squamous Cell Carcinoma
This trial is testing chemotherapy with or without bevacizumab to see how well it works in treating patients with head and neck squamous cell carcinoma that has come back or spread to other parts of the body.
Alkylating agents
Capecitabine + Intraperitoneal Oxaliplatin + Bevacizumab for Peritoneal Cancer
This trial is testing a new cancer treatment combining two drugs, one given directly into the abdomen and one taken by mouth. It is for people with a certain kind of cancer that has spread into the abdomen, and who have had surgery to remove as much of the cancer as possible.
Alkylating agents
Paclitaxel + Carboplatin or Ifosfamide for Uterine, Ovarian, Fallopian Tube, or Peritoneal Cavity Cancer
This trial is testing how well two different chemotherapy drugs work compared to each other in treating patients with fallopian tube or peritoneal cavity cancer.
Phase 3 Head And Neck Squamous Cell Carcinoma Clinical Trials
View 97 phase 3 head and neck squamous cell carcinoma medical studies.
Hormone Therapy
Tamoxifen Citrate or Letrozole + Bevacizumab for Stage IIIB or Stage IV Breast Cancer
This trial is testing tamoxifen citrate or letrozole with or without bevacizumab to treat stage IIIB or IV breast cancer. Estrogen fuels breast cancer cell growth, so hormone therapy with tamoxifen or letrozole can block estrogen and stop tumor growth. Bevacizumab is an immunotherapy that may help the body's immune system fight the cancer. Researchers want to see if it is more effective with or without bevacizumab.
Alkylating agents
Chemotherapy + Bevacizumab for Head and Neck Squamous Cell Carcinoma
This trial is testing chemotherapy with or without bevacizumab to see how well it works in treating patients with head and neck squamous cell carcinoma that has come back or spread to other parts of the body.
Alkylating agents
Carboplatin + Paclitaxel + Gemcitabine Hydrochloride with or without Bevacizumab for Recurrent Ovarian, Epithelial, Primary Peritoneal, or Fallopian Tube Cancer
This trial is studying carboplatin, paclitaxel, and gemcitabine hydrochloride given together with or without bevacizumab after surgery to treat patients with ovarian, epithelial, primary peritoneal, or fallopian tube cancer.
Platinum-based Chemotherapy
Radiation Therapy + Chemotherapy for Cervical Cancer
This trial compares radiation therapy with chemotherapy to radiation therapy alone to see which is more effective in treating patients with early cervical cancer who have already undergone surgery.
Head And Neck Squamous Cell Carcinoma Clinical Trials With No Placebo
View 97 head and neck squamous cell carcinoma medical studies that do not have a placebo group.
Monoclonal Antibodies
Imatinib + Cetuximab for Oral Squamous Cell Carcinoma
This trial tests whether a protein in cancer cells can predict how head and neck tumors respond to a combination of two treatments. Participants will be monitored for 13-16 months to assess the effectiveness.
Behavioral Intervention
Navigation for Squamous Cell Carcinoma
This trial is testing a new patient navigation intervention to decrease delays and racial disparities in postoperative radiation therapy (PORT) after surgery for head and neck cancer squamous cell carcinoma (HNSCC).
View More Head And Neck Squamous Cell Carcinoma Trials
See another 68 many medical studies focused on head and neck squamous cell carcinoma.
Frequently Asked Questions
Introduction to head and neck squamous cell carcinoma
What are the top hospitals conducting head and neck squamous cell carcinoma research?
When it comes to cutting-edge clinical trials for head and neck squamous cell carcinoma, several top hospitals are leading the way in research and innovation. Located in Duarte, California, City of Hope Comprehensive Cancer Center offers an impressive 19 ongoing trials focused specifically on this type of cancer. While they have yet to conduct any previous studies in this area, their dedication to combating head and neck squamous cell carcinoma is evident.
Similarly committed to finding new treatments and strategies is the University of California Davis Comprehensive Cancer Center in Sacramento. With 19 active clinical trials solely dedicated to head and neck squamous cell carcinoma, they too have not conducted any previous studies but remain steadfast in their pursuit of advancements.
Heading over to Houston, Texas, we find M D Anderson Cancer Center making significant strides with 18 ongoing clinical trials for head and neck squamous cell carcinoma. Like the other hospitals mentioned above, they also do not have a recorded history of past trials specific to this condition; however, their current efforts showcase their commitment towards future breakthroughs.
Closer to Los Angeles lies Providence Saint Joseph Medical Center/Disney Family Cancer Center located in Burbank where researchers are actively conducting 18 clinical trials focusing on head and neck squamous cell carcinoma treatment without having carried out prior investigations thus far.
Finally reaching Berkeley's Alta Bates Summit Medical Center-Herrick Campus which contributes significantly as well through its participation involving seventeen concurrent tests pertaining exclusively towards patients suffering from Head & Neck Squamous Cell Carcinoma despite lack historical data regarding earlier undertakings until now
These esteemed institutions serve as beacons of hope for those battling or affected by head and neck squamous cell carcinoma. Through collaborative efforts within these medical centers across various locations nationwide there exists strong belief that every trial brings us closer towards pioneering discoveries that would potentially revolutionize treatment options available thereby enhancing quality life countless individuals grappling such ailment face
Which are the best cities for head and neck squamous cell carcinoma clinical trials?
When it comes to head and neck squamous cell carcinoma clinical trials, several cities in the United States emerge as key hubs for research and treatment. Anchorage, Alaska boasts an impressive 84 active trials, focusing on the efficacy of Bevacizumab, Tamoxifen Citrate, Arm III (anastrozole and fulvestrant), among others. Oakland, California follows closely behind with 75 ongoing studies exploring treatments such as Bevacizumab, Trastuzumab, Paclitaxel. Additionally, Denver, Colorado has 73 active trials investigating the potential benefits of Bevacizumab,Paclitaxel,Therapeutic Conventional Surgery,and more. These cities offer individuals diagnosed with head and neck squamous cell carcinoma access to cutting-edge clinical trials that pave the way for advancements in care and improved outcomes.
Which are the top treatments for head and neck squamous cell carcinoma being explored in clinical trials?
Clinical trials for head and neck squamous cell carcinoma are investigating several promising treatments. Leading the pack is pembrolizumab, a groundbreaking immunotherapy drug that has shown significant efficacy in multiple trials. Another contender is cetuximab, a targeted therapy specifically designed to tackle this type of cancer. Additionally, researchers are exploring the potential of combination therapies such as docetaxel plus cisplatin and radiation therapy with chemotherapy drugs like fluorouracil. These innovative approaches bring hope for improved outcomes in patients battling head and neck squamous cell carcinoma.
What are the most recent clinical trials for head and neck squamous cell carcinoma?
Promising advancements in the treatment of head and neck squamous cell carcinoma have emerged from recent clinical trials. In particular, Nivolumab has shown encouraging results as a potential therapy for this type of cancer. Additionally, various treatment combinations involving cisplatin, docetaxel, nintedanib, crizotinib, erlotinib hydrochloride, and nab-paclitaxel are being investigated to improve outcomes for patients with head and neck squamous cell carcinoma. These trials offer hope for enhanced therapeutic options that can make a significant difference in the lives of individuals affected by this challenging disease.
What head and neck squamous cell carcinoma clinical trials were recently completed?
Several clinical trials focusing on head and neck squamous cell carcinoma have recently concluded, showcasing advancements in treatment options for this aggressive form of cancer. Notably, a trial sponsored by the University of Texas MD Anderson Cancer Center investigating pembrolizumab reached completion in September 2021. Another significant milestone was achieved with the conclusion of a study led by Memorial Sloan Kettering Cancer Center, evaluating the efficacy of nivolumab combined with ipilimumab in treating advanced-stage head and neck squamous cell carcinoma. These completed trials demonstrate ongoing efforts to improve outcomes and enhance therapeutic strategies against this challenging disease.