← Back to Search

Corticosteroid

GAE with Embosphere Microspheres for Knee Osteoarthritis (MOTION Trial)

N/A
Recruiting
Led By Sandeep Bagla, MD
Research Sponsored by Merit Medical Systems, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 3, 6, 12 and 24 months
Awards & highlights

MOTION Trial Summary

This trial will study if a new procedure (GAE) is better than a steroid injection to treat knee osteoarthritis symptoms over 2 years.

Who is the study for?
This trial is for adults over 21 with knee osteoarthritis who still have pain (score of ≥4 out of 10) despite trying other treatments for at least 3 months. It's not suitable for those planning major surgeries within a month, with advanced artery disease, previous knee replacement on the affected knee, or arthritis due to rheumatoid or infection.Check my eligibility
What is being tested?
The study compares two treatments for knee osteoarthritis: genicular artery embolization (GAE) using Embosphere Microspheres and steroid injections. Participants will be randomly assigned to one treatment and followed up for two years to see which is more effective.See study design
What are the potential side effects?
Possible side effects from GAE may include discomfort at the injection site, bruising, and temporary numbness. Steroid injections can cause pain flare-ups, joint infection risks, skin discoloration around the injection area, and weakening of nearby bones.

MOTION Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 3, 6, 12 and 24 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 3, 6, 12 and 24 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Primary Efficacy Endpoint
Primary Safety Endpoint
Secondary outcome measures
Numerical rating scale (NRS)
Subjects achieving Clinical Success

MOTION Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Genicular artery embolization with Embosphere MicrospheresExperimental Treatment1 Intervention
Device: Embosphere Microspheres Embolic Agent: Embosphere Microspheres
Group II: Corticosteroid Injection of the kneeActive Control1 Intervention
Drug: Corticosteroid injection

Find a Location

Who is running the clinical trial?

Merit Medical Systems, Inc.Lead Sponsor
30 Previous Clinical Trials
3,391 Total Patients Enrolled
Sandeep Bagla, MDPrincipal InvestigatorProstate Centers, USA
3 Previous Clinical Trials
288 Total Patients Enrolled
Craig J McAsey, MDPrincipal InvestigatorAnderson Orthopedic Clinic

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the age bracket for this trial restricted to adults under 45?

"This medical research is available to all patients aged 21 and under 100 years."

Answered by AI

In what geographic areas can this experiment be accessed?

"Patients can join this clinical trial at ECCO Medical in Lone Tree, Colorado; University of Miami in Florida; and Emory University School of Medicine in Georgia. In addition, there are another 23 sites that have been approved to enroll participants."

Answered by AI

Is there any possibility for me to join this medical experiment?

"This study is seeking 264 osteoarthritis-affected patients that are aged between 21 and 100."

Answered by AI

Are there vacancies in this clinical trial still available for participants?

"Evidenced by the information found on clinicaltrials.gov, this medical experiment is not actively recruiting patients at present. The trial was initially listed on January 1st 2024 and has since been modified for the last time back in October 12 2023. Though no longer enrolling participants, there are 693 other studies that require enrolment right now."

Answered by AI

Who else is applying?

What site did they apply to?
El Camino Hospital
Emory University School of Medicine
Cornell University, New York Presbyterian
Other
What portion of applicants met pre-screening criteria?
Met criteria

Why did patients apply to this trial?

I have said condition in my right knee. I have had osteoarthiris in shoulders and knees for years and would like to get relief.
PatientReceived no prior treatments
Recent research and studies
clinicaltrials.govStudy
GAE Using Embosphere Microspheres vs Corticosteroid Injections for Treatment of Symptomatic Knee OA
2024. "GAE Using Embosphere Microspheres vs Corticosteroid Injections for Treatment of Symptomatic Knee OA". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05818150.
~176 spots leftby Apr 2026
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top