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Orthopedic Implant

Knee Replacement for Osteoarthritis

N/A
Waitlist Available
Research Sponsored by Zimmer Biomet
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patient 18-75 years of age, inclusive
Patient qualifies for primary total knee arthroplasty based on physical exam and medical history
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 10 years
Awards & highlights

Study Summary

This trial is testing the Persona knee implant to see how well it works and how long it lasts.

Who is the study for?
This trial is for adults aged 18-75 with severe knee pain and disability due to conditions like osteoarthritis or rheumatoid arthritis, among others. Candidates must need a total knee replacement, be able to consent, and commit to follow-up evaluations. Exclusions include those in other studies, with certain bone/muscle diseases, previous knee replacements on the same side, or infections affecting the joint.Check my eligibility
What is being tested?
The study aims to collect data on the performance of Persona fixed bearing knee implants used in total knee arthroplasty (knee replacement surgery). It will focus on how long the implant lasts (implant survivorship) and how well it works clinically for patients who receive it.See study design
What are the potential side effects?
While not specified here, typical side effects from similar surgeries may include pain at the surgery site, swelling around the knee area, infection risk at incision sites or inside the joint space itself. There might also be risks related to anesthesia during surgery.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am between 18 and 75 years old.
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I am eligible for a knee replacement based on my doctor's assessment.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~10 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 10 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Knee Society Score
Secondary outcome measures
EQ-5D

Trial Design

1Treatment groups
Experimental Treatment
Group I: PERSONA TKAExperimental Treatment1 Intervention
Primary total knee arthroplasty subjects that receive the Zimmer Persona Total Knee System
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Zimmer Persona Total Knee System
2013
N/A
~300

Find a Location

Who is running the clinical trial?

Zimmer BiometLead Sponsor
373 Previous Clinical Trials
66,658 Total Patients Enrolled
129 Trials studying Osteoarthritis
32,387 Patients Enrolled for Osteoarthritis
Kacy Arnold, RN, MBAStudy DirectorZimmer Biomet
15 Previous Clinical Trials
3,265 Total Patients Enrolled
11 Trials studying Osteoarthritis
2,414 Patients Enrolled for Osteoarthritis

Media Library

Zimmer Persona Total Knee System (Orthopedic Implant) Clinical Trial Eligibility Overview. Trial Name: NCT02255383 — N/A
Osteoarthritis Research Study Groups: PERSONA TKA
Osteoarthritis Clinical Trial 2023: Zimmer Persona Total Knee System Highlights & Side Effects. Trial Name: NCT02255383 — N/A
Zimmer Persona Total Knee System (Orthopedic Implant) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02255383 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is registration open for this exploration?

"Unfortunately, this trial is no longer seeking patients for participation. Initially posted on July first 2014 and last updated November ninth 2022, alternate research options are available with 994 clinical trials currently recruiting test subjects."

Answered by AI

Are individuals aged 55 and above eligible to participate in this research trial?

"To be eligible for this trial, applicants must have an age between 18 and 75. There are 90 studies reserved for minors aged under 18 years old and 901 trials designed to benefit patients over 65."

Answered by AI

What prerequisites must a participant fulfill to be eligible for this investigation?

"This clinical trial is seeking 737 individuals afflicted with polyarthritis between the ages of 18 and 75. The prerequisites for enrollment include: suffering from rheumatoid arthritis, osteoarthritis, traumatic arthritis, polyarthritis; collagen disorders or avascular necrosis of the femoral condyle; post-traumatic loss of joint configuration due to patellofemoral erosion or dysfunction; moderate valgus, varus or flexion deformities caused by a failed surgical attempt that did not involve partial/total knee arthroplasty on ipsilateral knee; being eligible for commercially available Persona fixed bearing knee components implanted in accordance"

Answered by AI

Who else is applying?

What site did they apply to?
Tennessee Orthopaedic Foundation for Education and Research
What portion of applicants met pre-screening criteria?
Did not meet criteria
Recent research and studies
clinicaltrials.govStudy
Persona Total Knee Arthroplasty Outcomes Study
2014. "Persona Total Knee Arthroplasty Outcomes Study". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02255383.
All > Tennessee > Virginia
~102 spots leftby Dec 2025
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