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Local Anesthetic

ultra-sound guided femoral nerve block for Hip Fracture

N/A

Recruiting

Led By Beatrice Hoffmann, MD PhD

Research Sponsored by Beth Israel Deaconess Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 4 hours after initiation of study proceduure

Awards & highlights

Study Summary

This trial will compare pain control in people with hip fractures who receive ultrasound-guided femoral nerve blocks to those who receive the standard pain management of an injection of opioid medication.

Who is the study for?

This trial is for adults over 18 who come to the emergency department with a confirmed hip fracture and have moderate to severe pain. They must be able to give consent and participate in the study.Check my eligibility

What is being tested?

The study compares two methods of pain management for hip fractures: Ultrasound Guided Femoral Nerve Blockade (USFNB) using bupivacaine versus standard opioid medication like morphine given through injection.See study design

What are the potential side effects?

Possible side effects may include discomfort at the injection site, potential nerve damage from incorrect needle placement, allergic reactions to bupivacaine or morphine, and typical opioid-related side effects such as nausea, drowsiness, or constipation.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 4 hours after initiation of study proceduure

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~4 hours after initiation of study proceduure

This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 hours after initiation of study proceduure for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

pain intensity reduction

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: ultra-sound guided femoral nerve blockExperimental Treatment2 Interventions

Patients in this arm will receive a bed-side ultrasound guided femoral nerve block with analgesia 0.5% bupivacaine (2mg/kg)

Group II: standard of care- IV morphineActive Control1 Intervention

Patients in this arm will have the femoral nerve block block with no ultrasound for guidance with analgesia (IV morphine)

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Bupivacaine

FDA approved

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Beth Israel Deaconess Medical CenterLead Sponsor

837 Previous Clinical Trials

13,010,212 Total Patients Enrolled

Beatrice Hoffmann, MD PhDPrincipal Investigator - Beth Israel Deaconess Medical

Beth Israel Deaconess Hospital-Plymouth

Ruprecht-Karl-University (Medical School)

York Hospital (Residency)

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Do I meet the criteria to participate in this research project?

"Individuals aged between 18 and 101 years with a diagnosis of hip fracture are eligible for inclusion in this study, which aims to recruit approximately 60 participants."

Answered by AI

Are there any available positions for participants in this research study?

"The current status of this clinical trial, as indicated on clinicaltrials.gov, reveals an ongoing recruitment phase. Initial posting occurred on 1st August 2015 with the most recent update made on 2nd April 2024."

Answered by AI

What is the total number of participants being recruited for this clinical investigation?

"Indeed, as per the information on clinicaltrials.gov, this research endeavor is actively in search of suitable candidates. Originally shared on August 1st, 2015, the trial has since been revised most recently on April 2nd, 2024. A total of sixty participants are sought from a single designated site for enrollment."

Answered by AI

Are individuals who are older than 85 years eligible to participate in this study?

"Individuals eligible for participation in this research must be between 18 and 101 years old. Notably, there are separate trials available for those under 18 (12 studies) and individuals over the age of 65 (133 studies)."

Answered by AI

For what primary purpose is ultrasound-guided femoral nerve block typically prescribed?

"Conditions such as pemphigus, acute non-specific tenosynovitis, and the induction of general anesthesia may benefit from treatment with femoral nerve block guided by ultrasound."

Answered by AI

What additional medical studies have investigated femoral nerve block guided by ultrasound technology?

"Currently, there are 49 ongoing trials investigating the efficacy of ultrasound-guided femoral nerve block, with a significant portion in Phase 3. Philadelphia, Pennsylvania hosts multiple studies on this topic; however, across the nation, there are as many as 69 locations conducting research involving ultrasound-guided femoral nerve block."

Answered by AI

Recent research and studies

Annals of Emergency MedicineJournal

Three-in-one Femoral Nerve Block as Analgesia for Fractured Neck of Femur in the Emergency Department: A Randomized, Controlled Trial

Fletcher, Alan K., Alan S. Rigby, and Francis L.P. Heyes. 2003. “Three-in-one Femoral Nerve Block as Analgesia for Fractured Neck of Femur in the Emergency Department: A Randomized, Controlled Trial”. Annals of Emergency Medicine. Elsevier BV. doi:10.1067/mem.2003.51.

The Journals of Gerontology Series A: Biological Sciences and Medical SciencesJournal

Relationship Between Pain and Opioid Analgesics on the Development of Delirium Following Hip Fracture

Morrison, R. S., J. Magaziner, M. Gilbert, K. J. Koval, M. A. McLaughlin, G. Orosz, E. Strauss, and A. L. Siu. 2003. “Relationship Between Pain and Opioid Analgesics on the Development of Delirium Following Hip Fracture”. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. Oxford University Press (OUP). doi:10.1093/gerona/58.1.m76.

clinicaltrials.govStudy

Ultrasound Guided Femoral Nerve Block

Beatrice Hoffmann 2015. "Ultrasound Guided Femoral Nerve Block". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02381717.

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