SRP + Livfresh Dental Gel for Plaque, Dental

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Unversity of Alabama at Birmingham, School of Dentistry, Birmingham, AL
Plaque, Dental+5 More
SRP + Livfresh Dental Gel - Other
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will study whether Livionex Dental Gel, used at home, can reduce pocket depth beyond what is achievable with the current standard of care (scaling and root planing). The trial will test whether SRP + Livfresh Dental Gel is more effective than no treatment at reducing plaque and improving dental health after 12 weeks of treatment. Patients will be randomly assigned to either receive SRP + Livfresh Dental Gel or no treatment. The primary outcome measure will be the change in plaque scores from baseline to 12 weeks. Secondary outcome measures will include the change in gingival scores from baseline to 12 weeks and the change in number of teeth with plaque from baseline to 12 weeks.

Eligible Conditions

  • Plaque, Dental
  • Epulides
  • Pyorrhea Alveolaris
  • Gingival Pocket
  • Gingival Bleeding

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 3 Secondary · Reporting Duration: From baseline to 6 months

Month 6
Incremental reduction in Gingival Index
Incremental reduction in Plaque Index
Incremental reduction in gingival pocket depth.
Incremental reduction in the number of Bleeding on Probing (BOP)

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Scaling and Root Planing (SRP) + standard fluoride dentifrice
1 of 2
Scaling and Root Planing (SRP) + Livfresh Dental Gel (LDG)
1 of 2
Active Control
Experimental Treatment

76 Total Participants · 2 Treatment Groups

Primary Treatment: SRP + Livfresh Dental Gel · No Placebo Group · N/A

Scaling and Root Planing (SRP) + Livfresh Dental Gel (LDG)
Other
Experimental Group · 1 Intervention: SRP + Livfresh Dental Gel · Intervention Types: Other
Scaling and Root Planing (SRP) + standard fluoride dentifrice
Other
ActiveComparator Group · 1 Intervention: SRP + standard flouride dentifrice · Intervention Types: Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: from baseline to 6 months
Closest Location: Unversity of Alabama at Birmingham, School of Dentistry · Birmingham, AL
Photo of Birmingham 1Photo of Birmingham 2Photo of Birmingham 3
N/AFirst Recorded Clinical Trial
1 TrialsResearching Plaque, Dental
0 CompletedClinical Trials

Who is running the clinical trial?

University of Alabama at BirminghamLead Sponsor
1,403 Previous Clinical Trials
2,211,033 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 10 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You are a male or female at least 18 years of age.\n
You are available for the duration of the study.\n
You have at least 20 natural teeth.
You have at least 20 BOP sites.
You are willing and able to comply with study visits as described in the protocol.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.