This trial is testing a new cancer drug, in combination with an existing immunotherapy drug and chemotherapy, to see if it is effective in treating advanced head and neck squamous cell carcinoma.
- Head and Neck Cancer
- Head and Neck Squamous Cell Carcinoma (HNSCC)
2 Primary · 4 Secondary · Reporting Duration: Up to 36 months
2 Treatment Groups
Pembrolizumab + Chemotherapy
1 of 2
Evorpacept (ALX148) + Pembrolizumab + Chemotherapy
1 of 2
168 Total Participants · 2 Treatment Groups
Primary Treatment: Evorpacept · No Placebo Group · Phase 2
Who is running the clinical trial?
Age 18+ · All Participants · 4 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
Is the research team still accepting participants for this experiment?
"According to the details provided on clinicaltrials.gov, this medical trial is in its recruitment phase. Initially unveiled on May 10th 2021 and most recently updated by November 4th of that same year." - Anonymous Online Contributor
Has Evorpacept been examined in any other experiments?
"Evorpacept was first explored at City of Hope Comprehensive Cancer Center back in 1997. To date, 2336 trials have been finalized and there are presently 2142 live clinical tests ongoing, the majority being held in Louisville, Kentucky." - Anonymous Online Contributor
To what degree can Evorpacept be hazardous for human beings?
"Evorpacept's safety rating is a 2 on the scale of 1-3, since there are some risk assessments in place but no efficacy data has been collected." - Anonymous Online Contributor
What medical conditions is Evorpacept typically employed to alleviate?
"Evorpacept can be used to treat dangerous tumours, such as malignant neoplasms and unresectable melanoma, alongside microsatellite instability high." - Anonymous Online Contributor
How many participants are being monitored as part of this experiment?
"This clinical trial requires 168 suitable participants, and those interested can sign up at the University of Louisville in Kentucky or Rush University Medical Center in Illinois." - Anonymous Online Contributor
How many venues are involved in the execution of this scientific experiment?
"This trial is currently occurring in 7 different locales. Such places include Louisville, Chicago and Miami alongside 4 other cities. To avoid extensive commuting, it is recommended to join a centre nearby your current residence if you decide to take part." - Anonymous Online Contributor