This trial is evaluating whether Chocolate Touch will improve 2 primary outcomes and 3 secondary outcomes in patients with Ischemia. Measurement will happen over the course of 1 hour.
This trial requires 585 total participants across 2 different treatment groups
This trial involves 2 different treatments. Chocolate Touch is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"Patients with intermittent claudication can be successfully treated. The condition can be improved to the level that they will go on to walk without help. Although the condition of their hips may also have improved, patients continue to have chronic pain and an associated degree of activity restriction." - Anonymous Online Contributor
"Intermittent claudication is rarely relieved by surgery. Painkillers are sometimes effective but are generally not recommended as the sole treatment for the condition. Low-level exercise (e.g., walking or swimming) can help improve the condition in the short-term, but is less effective than a short duration of inelastic bandaging." - Anonymous Online Contributor
"Around 380,000 people in the United States are diagnosed with intermittent claudication. There are around 3.6 million new cases a year. This article is based on a review of the literature and excludes cases in early stage." - Anonymous Online Contributor
"Current data provide little information regarding the cause of intermittent claudication. The possibility of significant atherosclerosis in the claudication area could be considered, but this needs to be confirmed. In patients with severe claudication, atherosclerosis should be excluded after careful workup to rule out the possibility of renal artery stenosis causing intermittent claudication, although it may also be a common cause of intermittent claudication in the elderly. The most common cause of intermittent claudication in this age group remains hypertension." - Anonymous Online Contributor
"Intermittent claudication is a walking-related complication of peripheral arterial disease with a variable clinical and morphologic presentation that may be more common than currently appreciated." - Anonymous Online Contributor
"Intermittent claudication is an incidental finding on medical examination. It is an uncommon presentation but may be suggestive of other causes. The diagnostic procedure is simple and the results are of great clinical value." - Anonymous Online Contributor
"Chocolates may have a beneficial effect on treadmill walking in women with chronic intermittent claudication, as reported in observational studies. The effect may be partly mediated by the antioxidative properties of the polyphenols in cocoa and chocolate products. Further studies are needed to determine whether chocolate and cocoa products can be a therapeutic option for the management of claudication and to study the mechanisms of action." - Anonymous Online Contributor
"Even though patients report a significant improvement in chest pain and exercise tolerance after consuming chocolate, there is not high-quality evidence linking chocolate consumption and chest pain. We therefore conclude that more research is needed to determine if eating chocolate decreases, increases, or does not affect PAD." - Anonymous Online Contributor
"This survey showed high chocolate touch use with intermittent claudication (67.4%). If patients have tried any other treatment types used in combination with chocolate touch, see the table. If patients have never heard of, or never tried any treatment used in combination with chocolate touch, see the table." - Anonymous Online Contributor
"No significant advances in treatments were identified in our review. More studies are necessary to confirm safety and effectiveness of the treatments, with emphasis on new or alternative therapies, and to optimize pharmacotherapy for all patients with disabling intermittent claudication." - Anonymous Online Contributor
"The latest developments in chocolate touch involve improving the consistency of the product's chocolate coating, which in turn results in a better shelf life and, therefore, greater compliance with therapy." - Anonymous Online Contributor
"The concept of chocolate touch is not based on a scientific rationale, neither is it a therapeutic practice or a scientific basis to explain the clinical manifestation. A scientific rationale needs to be clearly provided and evidence-based. There is no conclusive evidence of the safety and efficacy of chocolate touch. Based on the current evidence, this practice should be avoided." - Anonymous Online Contributor