Cryoablation for Early-Stage Breast Cancer
(DCIS Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
Cryoablation or tumor freezing is a percutaneous, office-based procedure that is emerging as a minimally invasive, cost-effective alternative to surgery that is currently being evaluated in clinical trials for the management of for early-stage invasive breast cancer. The investigator will also evaluate the potential of cryoablation as a minimally invasive alternative to surgery for small areas of DCIS by examining its ability to achieve complete ablation of DCIS within the targeted cryoablation zone of necrosis.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
Is cryoablation safe for treating early-stage breast cancer?
How is the treatment Cryoablation different from other treatments for early-stage breast cancer?
What data supports the effectiveness of the treatment Cryoablation for Early-Stage Breast Cancer?
Research shows that cryoablation, a treatment that freezes cancer cells, is safe and can effectively control small breast tumors in many patients. It is performed using imaging techniques like ultrasound to guide the process, and it has been noted for its satisfactory cosmetic outcomes and minimal complications.467910
Are You a Good Fit for This Trial?
This trial is for individuals with a condition called Ductal Carcinoma In Situ (DCIS) in the breast, who haven't had surgery or radiation on the same breast. They should not be pregnant or have been pregnant in the last 6 months and must have enough breast volume for cryoablation. The DCIS should span 2 cm or less as seen on mammography or MRI.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo cryoablation to achieve complete ablation of DCIS
Follow-up
Participants are monitored for completeness of ablation and recurrence of DCIS
Long-term follow-up
Participants are monitored for recurrence of invasive breast cancer
What Are the Treatments Tested in This Trial?
Interventions
- Cryoablation
Cryoablation is already approved in United States, European Union for the following indications:
Find a Clinic Near You
Who Is Running the Clinical Trial?
Glendale Adventist Medical Center d/b/a Adventist Health Glendale
Lead Sponsor
Helen Rey Breast Cancer Research Foundation
Collaborator
Doterra Healing Hands Foundation
Collaborator
California Oncology Research Institute
Collaborator