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MORE vs. CBT for Smoking Cessation

N/A
Recruiting
Research Sponsored by University of Missouri-Columbia
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Age 18 and up
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 7 weeks
Awards & highlights

Study Summary

This trial will compare the effectiveness of MORE and CBT in reducing smoking behavior.

Who is the study for?
This trial is for adults over 18 who speak English, want to quit smoking, and have smoked for at least two years. They must be able to see well enough (with glasses if needed) to do tasks and tests. People can't join if they're pregnant, claustrophobic, use certain drugs or psychotropic meds recently, have major neurological issues or untreated illnesses, or any psychosis.Check my eligibility
What is being tested?
The study compares the effectiveness of Mindfulness-Oriented Recovery Enhancement (MORE), which combines mindfulness with behavioral therapy to change reward processes in the brain; and Cognitive Behavioral Therapy (CBT), which helps understand how thoughts affect behavior on quitting smoking.See study design
What are the potential side effects?
Since MORE and CBT are non-medical treatments focusing on behavior modification and thought patterns respectively, they typically don't cause physical side effects but may lead to emotional discomfort as individuals confront their smoking habits.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am 18 years old or older.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~7 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 7 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Cigarette Smoking
Magnitude of change in fMRI brain connectivity
Magnitude of change in fMRI brain response to images

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: MOREExperimental Treatment1 Intervention
Group II: CBTActive Control1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Mindfulness-Oriented Recovery Enhancement (MORE)
2017
N/A
~230

Find a Location

Who is running the clinical trial?

Medical University of South CarolinaOTHER
932 Previous Clinical Trials
7,394,190 Total Patients Enrolled
24 Trials studying Tobacco Use Disorder
2,692 Patients Enrolled for Tobacco Use Disorder
University of Missouri-ColumbiaLead Sponsor
361 Previous Clinical Trials
627,794 Total Patients Enrolled
4 Trials studying Tobacco Use Disorder
183 Patients Enrolled for Tobacco Use Disorder

Media Library

Cognitive Behavioral Therapy (CBT) Clinical Trial Eligibility Overview. Trial Name: NCT03948893 — N/A
Tobacco Use Disorder Research Study Groups: CBT, MORE
Tobacco Use Disorder Clinical Trial 2023: Cognitive Behavioral Therapy (CBT) Highlights & Side Effects. Trial Name: NCT03948893 — N/A
Cognitive Behavioral Therapy (CBT) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03948893 — N/A
Tobacco Use Disorder Patient Testimony for trial: Trial Name: NCT03948893 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any open slots for participants in this medical experiment?

"Affirmative, clinicaltrials.gov data shows that this research endeavor is currently enrolling participants. The study was initially promulgated on December 19th 2019 and has been revised as of March 18th 2022. It expects to recruit 200 patients from two separate sites."

Answered by AI

What is the current capacity in terms of participants for this research endeavor?

"Affirmative. The clinical trial page on clinicaltrials.gov confirms that the study, first posted December 19th 2019 and most recently updated March 18th 2022, is actively enlisting 200 subjects at 2 different sites."

Answered by AI

Who else is applying?

What state do they live in?
Missouri
What site did they apply to?
University of Missouri - Columbia
Medical University of South Carolina
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
1

Why did patients apply to this trial?

I'm ready to start living a healthier lifestyle.
PatientReceived 1 prior treatment
Recent research and studies
clinicaltrials.govStudy
Smoking Cessation Behavioral Treatment Study
Brett Froeliger 2019. "Smoking Cessation Behavioral Treatment Study". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03948893.
All > Smoking > Smoking Cessation
~37 spots leftby Apr 2025
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