This trial is evaluating whether Prolonged inflation will improve 3 primary outcomes and 4 secondary outcomes in patients with Coronary Artery Disease. Measurement will happen over the course of Day 1 Within first hour after after stent deployment.
This trial requires 40 total participants across 2 different treatment groups
This trial involves 2 different treatments. Prolonged Inflation is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"It is important for physicians to be aware that there is significant risk for the development of pneumothorax, rib fractures, and increased bleeding after prolonged inflation." - Anonymous Online Contributor
"Recent findings demonstrates a new technique for prolonged chest wall inflation that may facilitate hemostasis and prevention of pulmonary embolism for patients requiring major chest surgery." - Anonymous Online Contributor
"Most of the signs of CAD are non-specific and are not specific to CAD. It should, therefore, be determined in the clinical context which signs of CAD most commonly occur in this cohort." - Anonymous Online Contributor
"Coronary artery disease consists of two conditions: stable angina (heart attack) and unstable angina. The first is a heart muscle attack and the second is a heart attack of insufficient oxygen supply to the heart muscle. Patients may experience coronary artery disease before being diagnosed with a heart attack. Often, patients have no symptoms before experiencing the acute heart attack. Patients are at greater risk after the sudden heart attack with more chest pains and palpitations. A cardiac catheterization is needed if coronary artery disease is suspected. Coronary artery disease affects an estimated 5 million people every year, of whom half are women. This is a large number of people with coronary artery disease that have not yet been diagnosed." - Anonymous Online Contributor
"CAD is a complex disease that has multiple causes, but many of these conditions can be prevented. The best way to prevent CAD is to abstain from smoking, exercise regularly, and eat a healthy diet." - Anonymous Online Contributor
"coronary artery disease is caused by a complex interplay of genetic and environmental influences. Some of these influences can be modified through dietary, stress, exercise, or social influences. While coronary artery disease-associated risk factors are well understood, many questions remain unanswered relating to optimal management for individuals who are diagnosed with the disease. The aim of this article is to discuss aspects of optimal management of coronary artery disease in a conceptual manner based on existing evidence from a systemic literature review and on knowledge gained from the clinical experience of the authors." - Anonymous Online Contributor
"In a recent study, findings shows that the number of cases of CAD has fluctuated for decades. In the last few years the number of new cases has decreased and the proportion of patients with CAD and stroke who are unaware of the condition have declined." - Anonymous Online Contributor
"There is a high proportion of asymptomatic patients with CAD in our population, and CAD was associated with high-risk factors. In a small proportion of patients with known or suspected CAD, surgery was feasible, but further treatment with PCI, CABG or ACEI was not feasible." - Anonymous Online Contributor
"This article reviewed the literature to determine whether prolonged inhalation inflation reduces ischemic complications associated with PCI in all revascularization patients. No evidence was found to support the use of prolonged inflation to increase the time the balloon is inflated prior to removing it. There is no evidence to support this technique. Nevertheless, inflation continues to remain an optimal therapeutic adjunct during PCI for all revascularization patients." - Anonymous Online Contributor
"While there are hundreds of studies being done, only a few are relevant for coronary disease, leading to limited recommendations based on evidence. There are many strategies that can help in coronary disease treatment, including physical activities and drugs therapy as lifestyle modification. There are also many medications that can help patients with angina. Many medications can prevent heart attack and help patients to reduce risks or risk of coronary artery disease. It is important for patients to understand what are the most current treatments for coronary disease, which ones are effective, and what the risks of these treatments are, as any risks is important to be taken into consideration." - Anonymous Online Contributor
"Individuals with established coronary disease and/or myocardial infarction and with stable heart failure or congestive heart failure are eligible for coronary artery disease clinical trials. As of 2009, no trial has demonstrated superior outcomes when targeted to these groups. Inclusion criteria for clinical trials should include age 60 and older." - Anonymous Online Contributor
"PTA balloon inflation has become an accepted treatment option due to the many benefits, such as improved coronary blood flow, prevention of thrombosis, and improved myocardial functioning and preservation. While a prolonged balloon inflation is most effective for balloon-only PCI, we have expanded the indications of PTA by incorporating the use of a longer inflation time. In a case with multivessel coronary arterial disease, a prolonged PTA inflation is also feasible and has the additional benefit of suppressing the clotting reaction during balloon inflation." - Anonymous Online Contributor