Browse 29 Ivf Medical Studies Across 39 Cities
2 Phase 3 Trial · 53 Ivf Clinics
What Are IVF Clinical Trials?
IVF is a process whereby an individual goes through In Vitro Fertilization. This medical procedure is usually undertaken by individuals who cannot fall pregnant due to fertility complications from either party in the couple.
It’s estimated that around one in every ten women (or 10%) within the childbearing age group have PCOS, which has caused a significant spike in couples and single women seeking this treatment.
However, couples also use this treatment when trying to fall pregnant via a donor or surrogate.
In Vitro Fertilization is a complicated process. It involves monitoring a woman's menstrual cycle to pinpoint ovulation and removing viable ovum. The ovum is combined with sperm in Vitro, meaning that it is combined outside of biological means. In this case, the sperm and ovum are combined in a test tube to create potentially viable embryos.
The viable embryos are then transplanted into the woman's uterus in the hopes of the embryo attaching and resulting in pregnancy. But this process is costly and may not result in pregnancy. So, medical professionals and researchers need to practice clinical trials for this treatment to streamline it and get more positive results.
These trials are undertaken in the hopes of helping more couples get pregnant and have a higher success rate. As more individuals and treatment methods are studied, researchers may be closer to finding more proficient methods.
Why Is IVF Being Studied Through Clinical Trials?
With over a million babies born through IVF in the United States alone, In Vitro Fertilization is becoming an increasingly popular method for many couples. This treatment still leaves something to be desired, as the number of positive pregnancies increases only after several rounds of IVF. The average number of treatments needed for a woman under 30 is three, which can become expensive.
Generally, IVF treatments are expensive, which puts many infertile couples at a disadvantage. But, through research and determination, medical professionals and researchers hope to find more successful forms of IVF therapies and significantly reduce the cost to make it a more accessible form of infertility treatment.
What Are The Types of Treatments Available For IVF?
Because IVF is partly a 'guessing game,' medical professionals trained in IVF treatments can only estimate the success rate of the treatment. For some women, IVF treatment is unsuccessful, even after multiple rounds.
To further research on the best diagnostic methods for infertility causes, fertility treatments to rival IVF, better treatment methods, and how to increase success rates, IVF trials are usually done on women within childbearing age. However, some women over 40 are needed for experimental trials to help potential geriatric pregnancies (or pregnancies outside of childbearing age).
Several clinical trials are available for all women who are undergoing or want to undergo IVF treatment, including those for drugs that may induce ovulation. These trials will hopefully make it more likely to achieve a successful outcome when doing IVF treatments.
What Are Some Recent Breakthrough Clinical Trials For IVF?
With IVF becoming an increasingly popular fertility treatment, researchers have made several important discoveries through clinical trials that may help future couples conceive. These discoveries include:
2009: Fast Track IVF Treatment – In a significant clinical trial by researchers in New England, research has shown that a fast-tracked or accelerated IVF approach proved more successful than standard treatments. The approach involved pre-treatment subcutaneous drugs before treatment, resulting in more successful births and more pregnancies after fewer treatments.
2018: Embryo Transfers – A New England study of 2157 women undergoing IVF treatment revealed little difference in results between women who received fresh embryos and frozen ones. However, it was found that using frozen embryos resulted in fewer cases of OHSS or ovarian hyperstimulation syndrome, which comes from a change in hormones during treatment.