Fast Automated Cognitive Test Battery for Cognitive Decline

Recruiting · 18+ · All Sexes · Berkeley, CA

This study is evaluating whether a computerized test can help detect age-related cognitive decline.

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About the trial for Cognitive Decline

Eligible Conditions
Cognitive Decline · Cognitive Dysfunction · Alzheimer Disease · Aging

Treatment Groups

This trial involves 4 different treatments. Fast Automated Cognitive Test Battery is the primary treatment being studied. Participants will be divided into 4 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Experimental Group 1
Fast Automated Cognitive Test Battery
Experimental Group 2
California Cognitive Assessment Battery
Experimental Group 3
California Cognitive Assessment Battery
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This trial is for patients born any sex aged 18 and older. There are 2 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
Must be proficient in speaking, reading, and writing English Must be a U.S show original
Can use a computer mouse and touch screen. show original
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Odds of Eligibility
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial
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Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: Longitudinal testing at six-month intervals
Screening: ~3 weeks
Treatment: Varies
Reporting: Longitudinal testing at six-month intervals
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: Longitudinal testing at six-month intervals.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Fast Automated Cognitive Test Battery will improve 1 primary outcome in patients with Cognitive Decline. Measurement will happen over the course of Longitudinal testing at six-month intervals.

Longitudinal normative data collection from healthy participants
Multiple behavioral outcome measures will be obtained from each cognitive test including measures of response time (in milliseconds) and accuracy (in percent correct). Recordings of subject's verbal responses will also be analyzed phonologically and automatically transcribed to permit the lexical, syntactic, and semantic analysis of speech output. Researchers will also obtain saliva samples of DNA from participants 60 years of age and older and analyze them for the presence of the APOE epsilon 4 variant. Questionnaire data will be used to identify factors that may influence performance on the cognitive tests. The primary outcome measures are the scores obtained during enrollment testing that predict a decline in longitudinal performance.

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is cognitive decline?

Cognitive decline is a long-term deterioration in cognitive function. In many cases, the cognitive functions may be less severely affected by the decline than the individuals would recognize. Older adults may experience cognitive decline, but it differs in degree according to age and gender.

Anonymous Patient Answer

What are common treatments for cognitive decline?

Cognitive decline can be very treated with multifactorial interventions, such as medications, and many of them can prevent progression of cognitive decline. Cognitive decline does not cure but it can prolong life by preventing sudden death. There is still no known cure for cognitive decline but it can be delayed or prevented to reduce burden on the patient and family. The treatments mentioned below are not an exhaustive list, but they are effective as of now. To find more treatments for cognitive decline, a systematic review is in preparation.

Anonymous Patient Answer

What causes cognitive decline?

Age is the single factor that most reliably predicted functional decline. The associations of APOE and P-PAR suggest that other genetic and environmental risk factors are probably involved. Given the strong associations with decline, this suggests that lifestyle and environmental factors could be of particular importance.

Anonymous Patient Answer

How many people get cognitive decline a year in the United States?

Both men and women have an increased risk for cognitive impairment as they age. Between age 65 and 85, 8.6% of men and 8.1% of women suffer cognitive decline in the form of mild cognitive impairment or dementia.

Anonymous Patient Answer

Can cognitive decline be cured?

Using Power or [Stroboe-Mole Clinic's(], you can easily find one that has a treatment plan specific to your condition. If you are interested in joining a clinical trial using a cognitive training program, send a doctor's note as soon as possible. You'll need your trial form once you buy. (http://www.stroboe-mole.

Anonymous Patient Answer

What are the signs of cognitive decline?

In the present day, cognitively impaired adults often display signs of impaired executive functioning and impairments in memory that can be easily tracked in daily life. In the elderly, cognitive disorder is often associated with decline in cognitive status or decline in performance. As the cognitive functions can be assessed via cognitive testing, the risk of developing a dementia can be predicted.

Anonymous Patient Answer

Has fast automated cognitive test battery proven to be more effective than a placebo?

In a recent study, findings of present study suggest that using FastACCTs in combination with some of known neuroimaging correlates of executive functions may be useful in detecting early cognitive decline in population at risk for dementias such as MCI and AD.

Anonymous Patient Answer

Have there been other clinical trials involving fast automated cognitive test battery?

Clinical trials evaluating FACT-COG have been conducted and it is likely that the outcomes may be different when comparing patients to the general population as well as from trial itself. Better patient outcome in trials versus real-world settings may be the result of more thorough assessment of patients, and/or a consequence of better adherence to experimental therapy versus untreated patients.

Anonymous Patient Answer

Have there been any new discoveries for treating cognitive decline?

While there are ongoing clinical trials for the prevention of Alzheimer's disease, there have not been any new medications developed for treating this devastating disorder. This could be because many patients with Alzheimer's disease have an abnormal buildup of beta-amyloid protein in their brain (a buildup of Amyloid-beta), which is implicated in and triggers the progression of the disease.

Anonymous Patient Answer

Is fast automated cognitive test battery safe for people?

Fast automated cognitive test batteries are safe for routine clinical use, and clinicians can use them to detect subtle cognitive impairment in primary care. These automated tests were associated with good sensitivity but poor specificity. Their use may result in misdiagnosis but with potentially favourable repercussions on patient management.

Anonymous Patient Answer

What is the latest research for cognitive decline?

Although it is [very difficult to study in its own right; one needs to compare the findings from multiple research in one region] [cites a recent cohort study that found no association between cognitive decline and infertility as well as a review from 2014 that found no association between cognitive decline and men's perceptions of their health]. There is still no evidence-based conclusion about the effectivity of any drug for treating [cognitive decline] after being told that you will lose your ability to think. Researchers have reported many conflicting findings because of different study population and [outcome measures], and so there is no one way to tackle [covid_19 in the brain].

Anonymous Patient Answer

How does fast automated cognitive test battery work?

The battery does not appear to be effective in detecting cognitive decline in healthy middle-aged adults, but it is likely to hold more promise as a screening tool in detecting early abnormalities before the clinical presentation of vascular dementia and/or mild cognitive impairment. [Power]

Anonymous Patient Answer
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