Computerized Cognitive Tests for Early Detection of Alzheimer’s Disease
Trial Summary
What is the purpose of this trial?
The investigators will study performance on computerized cognitive tasks in healthy participants of different ages to gather normative data for newly developed computerized cognitive tests. These tests are designed to permit the early detection of individuals at risk of age-related cognitive decline.
Do I need to stop taking my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment California Cognitive Assessment Battery (CCAB) and similar computerized cognitive tests for early detection of Alzheimer's disease?
Research shows that computerized cognitive tests, like the Computerized Self Test (CST) and the Cogstate Brief Battery (CBB), are effective in identifying cognitive impairment related to Alzheimer's disease. The CST accurately classified 96% of cognitively impaired individuals, outperforming traditional tests like the Mini-Mental Status Examination. Similarly, the CBB has been shown to detect early cognitive impairment in people at risk for Alzheimer's, making these tools promising for early detection.12345
Is it safe to participate in computerized cognitive tests for Alzheimer's detection?
How does the computerized cognitive test differ from other treatments for Alzheimer's disease?
The computerized cognitive test is unique because it offers an accessible, low-cost, and self-administered method for early detection of Alzheimer's disease, unlike traditional treatments that focus on managing symptoms. It eliminates the need for a rater, saving time and providing immediate results, which is not typical of other cognitive assessments.1891011
Eligibility Criteria
This trial is for healthy individuals who can use a computer mouse and touchscreen, and speak English or Spanish as their primary language. It's not suitable for those with psychiatric disorders, stroke history, substance abuse, medical conditions affecting testing, traumatic brain injury with hospitalization and extended unconsciousness, epilepsy, depression or anxiety.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Enrollment
Participants undergo initial cognitive testing for three days to gather baseline data
Longitudinal Testing
Participants are tested at 6-month intervals to collect longitudinal normative data
Follow-up
Participants are monitored for changes in cognitive performance over time
Treatment Details
Interventions
- California Cognitive Assessment Battery
- Fast Automated Cognitive Test Battery
Find a Clinic Near You
Who Is Running the Clinical Trial?
Neurobehavioral Systems, Inc.
Lead Sponsor
National Institutes of Health (NIH)
Collaborator