We started Power when my dad was diagnosed with multiple myeloma, and I struggled to help him access the latest immunotherapy. Hopefully Power makes it simpler for you to explore promising new treatments, during what is probably a difficult time.
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"I have dealt with voice and vocal fold issues related to paralysis for over 12 years. This problem has negatively impacted virtually every facet of my life. I am an otherwise healthy 48 year old married father of 3 living. My youngest daughter is 12 and has never heard my real voice. I am now having breathing issues related to the paralysis as well as trouble swallowing some liquids. In my research I have seen some recent trials focused on helping people like me."
"As a healthy volunteer, I like to participate in as many trials as I'm able to. It's a good way to help research and earn money."
"I was diagnosed with stage 4 pancreatic cancer three months ago, metastatic to my liver, and I have been receiving and responding well to chemotherapy. My blood work revealed that my tumor markers have gone from 2600 in the beginning to 173 as of now, even with the delay in treatment, they are not going up. CT Scans reveal they have been shrinking as well. However, chemo is seriously deteriorating my body. I have 4 more treatments to go in this 12 treatment cycle. I am just interested in learning about my other options, if any are available to me."
"I changed my diet in 2020 and I’ve lost 95 pounds from my highest weight (283). I am 5’3”, female, and now 188. I still have a 33 BMI. I've been doing research on alternative approaches to continue my progress, which brought me here to consider clinical trials."
"My orthopedist recommended a half replacement of my right knee. I have had both hips replaced. Currently have arthritis in knee, shoulder, and thumb. I want to avoid surgery, and I'm open-minded about trying a trial before using surgery as a last resort."
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Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range for Phase 2–4 trials (Phase 1 trials often pay substantially more). Further, most trials will cover the costs of a travel to-and-from the clinic.
After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll be sorted into one of the treatment groups, and receive your study drug. For some trials, there is a chance you'll receive a placebo. Across Stroke trials 30% of clinical trials have a placebo. Typically, you'll be required to check-in with the clinic every month or so. The average trial length for Stroke is 12 months.
Not all studies recruit healthy volunteers: usually, Phase 1 studies do. Participating as a healthy volunteer means you will go to a research facility several times over a few days or weeks to receive a dose of either the test treatment or a "placebo," which is a harmless substance that helps researchers compare results. You will have routine tests during these visits, and you'll be compensated for your time and travel, with the number of appointments and details varying by study.
The phase of a trial reveals what stage the drug is in to get approval for a specific condition. Phase 1 trials are the trials to collect safety data in humans. Phase 2 trials are those where the drug has some data showing safety in humans, but where further human data is needed on drug effectiveness. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. As a general rule, Phase 3 trials are more promising than Phase 2, and Phase 2 trials are more promising than phase 1.
Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.
Most recently, we added MyStroke for Stroke Survivors, Glycerol Tributyrate for MELAS Syndrome and Optic Neuropathy and Motor Relearning and Sensory Rehabilitation for Stroke to the Power online platform.
A completely symptom-free recovery does happen, but it’s uncommon—about 1 in 10 stroke survivors have no noticeable deficits by 3–6 months, while many more regain independence yet live with minor limitations. Your odds rise if the stroke is small, treated within hours (clot-busting drugs or thrombectomy), and followed by early, high-intensity rehab; age, other illnesses, and strong family support also matter. Even when full recovery isn’t reached, the brain can keep rewiring for months or years, so aggressive therapy and strict control of blood pressure, cholesterol, and lifestyle risks remain worthwhile.
A stroke is triggered the instant blood can’t reach part of the brain—either because a clot suddenly blocks an artery or a weakened vessel bursts. Long-standing problems such as high blood pressure, atrial fibrillation, diabetes, smoking, and cholesterol build-up make the vessels fragile, while short-term sparks like a surge in blood pressure (heavy exertion, intense stress, cocaine or binge drinking), a bad infection, severe dehydration, or head/neck injury can tip things over the edge. Controlling the chronic risks and avoiding those sudden spikes are the surest ways to lower your odds.
Two main “new” procedures are worth knowing about. If a stroke is caught within the first day, doctors can now thread a tiny device into the brain’s artery (mechanical thrombectomy) to pull out large clots—even up to 24 hours after symptoms start. For people who are six months or more past an ischemic stroke and still have arm weakness, a recently approved treatment called paired vagus-nerve stimulation implants a pacemaker-like device in the chest; brief pulses are delivered during therapy sessions and, in a large study, nearly doubled the number of patients who regained meaningful arm use compared with therapy alone. Ask your stroke or rehab specialist which option, if any, fits your stage of recovery and medical history.
Across contemporary U.S. and European studies, the average (mean) age at first ischemic stroke is about 70–72 years overall—roughly 71 years in men and 74–75 years in women. Most strokes still occur after 65, but nearly 15–20 % now happen before age 55, so personal risk depends more on controllable factors such as blood-pressure, diabetes, smoking, and atrial fibrillation than on age alone.
Good signs after a stroke are the things doctors see when the brain is healing: 1) steadily improving neurological function—e.g., a weak arm or leg starts to move, speech becomes clearer, swallowing is safe, thinking is sharper; 2) growing independence—being able to sit, stand, walk, dress, or bathe with less help each week; and 3) no new problems—vital signs remain stable, follow-up scans show no bleeding or new damage, and there are no new bouts of confusion or weakness. If progress keeps inching forward over the first days to months, that generally predicts a better long-term recovery, while sudden setbacks should prompt a call to the medical team.
Neither hemisphere is automatically “worse.” What harms you most is how big the stroke is, which critical areas it hits (for example, language centers on the left or spatial-awareness areas on the right), and how fast doctors can restore blood flow. Large right-side strokes carry a slightly higher risk of early swelling and heart-rhythm problems, while left-side strokes more often steal speech, but in the long run size, exact location, and treatment speed—not simple left vs. right—determine survival and disability.
A stroke in progress can only be halted by hospital teams, so the single lifesaving move is to get the patient to a stroke-ready ER fast. Spot symptoms with the BE-FAST check (Balance, Eyes, Face, Arm, Speech, Time), call 911, note when symptoms started, keep the person upright and nil-by-mouth, and let EMS transport. Every minute saved lets doctors give clot-busting medicine (within ~4½ h) or remove a clot mechanically (up to 24 h in select cases), drastically reducing brain damage and disability.
“Time is brain.” Call 911 the moment you notice stroke signs, because the sooner doctors see you, the more treatment choices you have: clot-busting medication helps most if started within 4½ hours, and a catheter procedure to pull out a large clot can work in carefully selected cases up to 24 hours—but outcomes get worse with every minute’s delay. Getting to the hospital fast also lets the team quickly scan your brain, control bleeding or swelling, and begin early rehab, all of which greatly improve the chance of recovery.
First, rapid hospital treatment (clot-busting drugs or a catheter procedure, plus careful control of blood pressure, sugar and swelling) “saves” threatened brain tissue—so minutes matter. In the weeks and months that follow, the surviving brain rewires itself and grows new blood vessels, and that self-repair works best when you give it the right signals: daily, task-specific rehab exercises, regular aerobic activity, good sleep, and strict control of smoking, blood pressure, cholesterol and diabetes; tools like non-invasive brain stimulation or certain medications are optional add-ons guided by specialists. Put simply, the brain heals through a mix of early damage-limiting care and long-term, repetitive practice in a healthy body, with emerging technologies offering extra (but still experimental) help for some people.
For patients able to tolerate intensive therapy, the average stay in a U.S. inpatient rehabilitation hospital is about 15–18 days (roughly 2–3 weeks); if a skilled-nursing rehab unit is needed, expect closer to 4–5 weeks before stepping down to outpatient or home therapy several times a week. How long you personally stay hinges on stroke severity, other medical problems, progress on daily-living skills, insurance rules, and the safety of your home setup—so ask the rehab team what specific goals you must meet to move to the next level of care.