VenaSeal™ Closure System for Venous Reflux

The national venous reflux rate with clinical diagnosis is about 28.5% and without clinical diagnosis is about 41%. Approximately 25% have significant reflux. We estimate 20% are affected with clinically significant disease.

Although no specific treatment for venous reflux appears to be proven effective, lifestyle modification is indicated if patients experience venous symptoms. Medication is a secondary form of treatment. Minimizing dietary fat is useful as a nonpharmacologic measure to limit the flow of gastric acids into the veins.

Venous reflux is a chronic, recurrent, often asymptomatic condition. Signs in symptomatic venous reflux patients frequently involve the arms, legs, torso, and sometimes head. A systematic examination, including an arm and leg examination will help to identify this condition.

Venous reflux is caused by two major conditions: esophageal motility disorders and/or paralysis of striated muscle pump. Treatment of the former cause may reduce the incidence of reflux and improve health-related quality of life.

Venous reflux may be partially caused by abnormalities in blood flow to lower limbs. When these abnormalities are corrected, the venous reflux improves or disappears.

Venous reflux is a condition that creates a problem for people with lower limbs venous ulcers. People with reflux are more likely to suffer venous ulcers.

Clinical trials are underused in this population. Physicians may be unaware of clinical trials available for treatment of venous reflux and its correlation with CVD.

Venaseal™ closure system does not compromise clinical outcome in PVI in terms of success rate. It can help PVI team to be more confident, because there is less need to worry about this device.

The average age of people with venous reflux is higher than that in the general population. Gender is the predominant factor associated with venous reflux.

Venous system closure devices are effective methods to decrease the recurrence of varicosity or esophageal varices in patients with varicose veins. Because of the rarity of varicose veins, venaseal closure devices are effective. Complications such as haemodialysis access are rare. Venaseal and Portacath"

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The current treatment is not as complete as it needs to be. The development of a new treatment is possible and will probably result in better results. The most difficult problem of treating venous reflux is to stop all reflux while treating it. It is possible that with a combined new treatment it will be possible to get rid of venous reflux. However, this will not be easy.