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Palliative Care for End Stage Liver Disease (PAL-LIVER Trial)
PAL-LIVER Trial Summary
This trial is comparing two ways of introducing palliative care for people with end stage liver disease - either by having direct access to a palliative care provider, or by training a hepatologist to deliver palliative care services. The primary outcome is the change in quality of life from baseline to 3 months post enrollment, as assessed by the Functional Assessment of Cancer Therapy- Hepatobiliary. 14 Clinical Centers across the US are recruited to participate in this study.
PAL-LIVER Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowPAL-LIVER Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.PAL-LIVER Trial Design
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Who is running the clinical trial?
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- Your liver disease is so severe (MELD score > 30) that you may not live more than 6 months.I have advanced liver disease or liver cancer and have a caregiver willing to participate.
- Group 1: Model 1: Consultative Palliative Care
- Group 2: Model 2: Trained Hepatologist- led PC
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is the age restriction for this medical trial limited to those younger than 45 years of age?
"As per the requirements for this medical trial, eligible candidates must be aged between 18 and 120."
How many sites are responsible for overseeing this clinical experiment?
"Loma Linda Unversity Health, Kansas City VA Medical Center and Medical University of South carolina are only a few of the 18 medical centres currently running this trial."
Is it possible to enroll in this trial at present?
"This clinical trial is attempting to recruit 1260 individuals suffering from chronic liver failure, aged between 18 and 120. Candidates must meet a few prerequisite criteria including being diagnosed with End Stage Liver Disease or Hepatocellular Cancer (no matter their transplant status) as well as having an accompanying caregiver that can be involved in the study."
Is recruitment still taking place for this research initiative?
"Affirmative. The information on clinicaltrials.gov confirms the recruitment status of this study, which was originally posted in January 2019 and last updated in April 2022. It requires 1260 volunteers from 18 different medical institutes to participate."
How many participants are being treated in this medical trial?
"Affirmative. According to clinicaltrials.gov, this research is actively seeking participants with an initial posting date of 1/30/2019 and a recent update on 4/5/2022. 1260 individuals must be recruited from 18 different medical centres for the trial to proceed."
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