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Advanced CT Imaging Techniques for Coronary Heart Disease

N/A
Recruiting
Led By Marcus Y Chen, M.D.
Research Sponsored by National Heart, Lung, and Blood Institute (NHLBI)
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Clinical indication for a coronary CT angiography exam
Age equal to or greater than 18 years
Timeline
Screening 3 weeks
Treatment Varies
Follow Up ongoing
Awards & highlights

Study Summary

This trial is studying new ways of taking pictures of the heart or blood vessels using computed tomography to see how effective they are in producing accurate CT scans.

Who is the study for?
This trial is for adults over 18 who need a coronary CT angiography exam to check their heart or blood vessels. They must understand and sign consent, be able to follow up, and have working kidneys if using contrast. Pregnant individuals or those with severe kidney issues can't join.Check my eligibility
What is being tested?
Researchers are testing new low-radiation techniques in the Toshiba Aquilion ONE CT system for imaging the heart and blood vessels. Participants will undergo a detailed scan session that could use a contrast agent and will be followed up after 90 days, then yearly for five years.See study design
What are the potential side effects?
Potential side effects may include reactions to the contrast agent used during scanning (if applicable), such as allergic reactions or kidney function impairment. The reduced radiation technique aims to minimize exposure-related risks.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I need a heart scan to check my arteries.
Select...
I am 18 years old or older.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~ongoing
This trial's timeline: 3 weeks for screening, Varies for treatment, and ongoing for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
new imaging methods are accurate or predict subject outcomes.
Secondary outcome measures
Estimate diagnostic accuracy of cardiovascular evaluations using new CT technology vs. invasive angiography and versus stress perfusion MRI.
Estimate radiation dose from clinically performed cardiovascular CT.
Evaluate image quality from new CT technology.
+1 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: 1Experimental Treatment1 Intervention
Subjects with Clinical indication for a coronary CT angiography exam

Find a Location

Who is running the clinical trial?

National Heart, Lung, and Blood Institute (NHLBI)Lead Sponsor
3,838 Previous Clinical Trials
47,846,654 Total Patients Enrolled
Marcus Y Chen, M.D.Principal InvestigatorNational Heart, Lung, and Blood Institute (NHLBI)
6 Previous Clinical Trials
6,412 Total Patients Enrolled

Media Library

The Toshiba Aquilion ONE CT system Clinical Trial Eligibility Overview. Trial Name: NCT01621594 — N/A
Coronary Heart Disease Research Study Groups: 1
Coronary Heart Disease Clinical Trial 2023: The Toshiba Aquilion ONE CT system Highlights & Side Effects. Trial Name: NCT01621594 — N/A
The Toshiba Aquilion ONE CT system 2023 Treatment Timeline for Medical Study. Trial Name: NCT01621594 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there an opportunity for me to take part in this medical experiment?

"This research is welcoming 5000 individuals, aged 18 and above, with coronary ailments. Those who wish to participate must meet the following criteria: be clinically suitable for a CT angiography exam, comprehend and agree to the informed consent form, as well as provide follow-up information if required."

Answered by AI

Is this research effort recruiting senior citizens?

"This clinical trial has set the age of eligibility at 18 to 100 years old. Subsequently, there are 7 studies targeting those below 18 and a separate 232 for individuals over 65."

Answered by AI

What are the main goals of this medical study?

"This clinical trial, with a duration of 90 days, is designed to determine whether new imaging methods can accurately forecast patient outcomes. Secondary objectives include evaluating image quality from the novel CT technology and assessing the diagnostic accuracy compared to invasive angiography and stress perfusion MRIs."

Answered by AI

Is this research endeavor actively seeking out participants?

"Affirmative. Clinicaltrials.gov records indicate that this study, initially posted on June 21st 2012, is still actively seeking participants. 5000 volunteers are required from two distinct locations to complete the trial."

Answered by AI

How many volunteers are engaged in the current clinical trial?

"Correct. According to details from clinicaltrials.gov, this medical trial is in its recruitment phase with a start date of June 21st 2012 and an update on November 24th 2022. Five-thousand individuals are being sought for the study at two distinct sites."

Answered by AI
Recent research and studies
~359 spots leftby Apr 2025