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64Cu-DOTA-ECL1i for Heart Attack
Study Summary
This trial will study whether the investigational drug 64Cu-DOTA-ECL1i is taken up by cells in the myocardium in people with a history of heart attack or other inflammatory heart disease.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Logistics
Participation is compensated
You will be compensated for participating in this trial.
Who is running the clinical trial?
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- My heart condition is not well-managed.You are currently using illegal drugs for fun.I can lie still for an hour and follow breathing instructions during a scan.I experience chest pain due to heart issues.I am a healthy volunteer already participating in another drug study.You weigh more than 300 pounds.I am between 21 and 80 years old and willing to volunteer for a study.You have a medical device inside your body that cannot be used with CT or MRI scans.Women who are not yet in menopause need to have a negative pregnancy test within 24 hours before taking the study drug 64-Cu-DOTA-ECL1i.I can sign consent and follow the study's procedures.I might not be able to complete all required study activities.You cannot have gadolinium for medical reasons.I do not have unstable heart conditions like severe uncontrolled blood pressure or recent heart attack.My blood pressure is either too high or below 90/50.I have or had heart, lung, liver, kidney problems or diabetes.You are afraid of being in small or enclosed spaces.I cannot have gadolinium contrast due to health reasons.I do not have a history of heart, lung, liver, kidney diseases or diabetes.I am between 21 and 80 years old and have had a severe heart attack or other inflammatory heart conditions in the last 6 months.I am currently on prescription medication.You have not used illegal drugs or inhaled drugs in the past year.My body weight is over 300 lbs.You cannot have a PET/CT scan because you have claustrophobia.
- Group 1: Cardiomyopathy
- Group 2: Infected Cardiovascular Implantable Electronic Devices
- Group 3: Post ST Elevation Myocardial Infarction/ Heart Attack
- Group 4: Myocarditis
- Group 5: Sarcoidosis
- Group 6: Healthy Volunteers
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Do individuals aged 55 and over qualify for this trial?
"This trial is recruiting participants of legal age (21 and above) who are also below the age of 80."
What requirements must be fulfilled to participate in this experiment?
"This clinical trial is recruiting 90 individuals aged 21 to 80 years old who suffer from cardiac conditions. Applicants must also meet the further criteria: no history of claustrophobia or other medical issue that interferes with imaging sessions, able and willing to understand and follow instructions for study procedures, clear of any known pulmonary, hepatic, renal diseases/diabetes, capable of remaining still in PET/CT scanners for one hour while following breathing protocol during CT portion, no illicit drug use within past year as well as patients suffering from Inflammatory Heart disease such as STEMI (within prior 6 months) and sarcoidosis/"
Are investigators still accepting new participants for the trial?
"Affirmative. Evidently, this research endeavour is presently recruiting participants. It was initially posted on November 24th 2018 and most recently modified on November 22nd 2022. The clinical trial requires 90test subjects from a single medical centre."
What is the current patient count for this clinical investigation?
"Affirmative. As per the clinicaltrials.gov webpage, this research study is presently recruiting participants; it was first uploaded on 24th November 2018 and recently revised on 22nd November 2022. The total number of trial members sought across one centre stands at 90 individuals."
To what extent can Cardiomyopathy have a detrimental effect on patients?
"The team at Power ranked the safety of Cardiomyopathy a 1, due to limited data surrounding its efficacy and no prior clinical evidence confirming protection."
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