PET-CT Scans for Head and Neck Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this study is to see how useful the information provided from Positron Emission Tomography (PET) scans can be in the actual planning and delivery of radiation treatment to patients who have head and neck cancers. Patients participating in this study, will have (in addition to their routine tests) a PET scan before and during their radiation treatment. Following the intervention, patients will be followed as per standard practice.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but it does exclude those who have had chemotherapy or are taking certain cancer drugs. It's best to discuss your specific medications with the trial team.
Is 18-F FDG PET-CT safe for humans?
How is PET-CT scanning unique in treating head and neck cancer?
PET-CT scanning is unique because it combines detailed anatomical images from CT scans with functional information from PET scans, helping to better stage the cancer, plan treatment, and monitor response. This approach can identify hidden metastases and improve the precision of radiotherapy, potentially sparing healthy tissue.36789
What data supports the effectiveness of the treatment 18-F FDG, Fluorodeoxyglucose F 18, FDG-PET, 18F-FDG for head and neck cancer?
Research shows that FDG-PET scans are highly effective in identifying head and neck tumors, with a sensitivity of 97%, meaning they correctly identify 97% of actual tumors. This method is more accurate than traditional CT scans and helps distinguish between tumor recurrence and treatment-related changes, potentially improving patient management and outcomes.310111213
Who Is on the Research Team?
John J Kim, MD
Principal Investigator
The Princess Margaret Cancer Foundation
Are You a Good Fit for This Trial?
This trial is for adults with non-nasopharynx head and neck cancers who haven't had chemotherapy or radiotherapy in the last 5 years. They should have visible cancer that's treatable with radiation alone, and a tumor that shows up on PET scans. Pregnant individuals or those unable to consent are excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Pre-treatment PET Scan
Participants undergo a PET scan before starting radiation treatment to assist in planning
Radiation Treatment
Participants receive radiation treatment with PET scans conducted during the treatment
Follow-up
Participants are monitored for safety and effectiveness after treatment as per standard practice
What Are the Treatments Tested in This Trial?
Interventions
- 18-F FDG
Find a Clinic Near You
Who Is Running the Clinical Trial?
University Health Network, Toronto
Lead Sponsor