Independent Control for COVID-19

Phase-Based Estimates
1
Effectiveness
1
Safety
Annenberg School for Communication, Philadelphia, PA
COVID-19+4 More
Independent Control - Behavioral
Eligibility
18+
All Sexes
Eligible conditions
COVID-19

Study Summary

Improving Health Equity for COVID-19 Vaccination for At-risk Populations Using Online Social Networks

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Eligible Conditions

  • COVID-19
  • Heart Diseases
  • Covid19
  • Vaccination Refusal
  • Contraception Behavior

Treatment Effectiveness

Study Objectives

This trial is evaluating whether Independent Control will improve 2 primary outcomes and 1 secondary outcome in patients with COVID-19. Measurement will happen over the course of Immediate after intervention.

Immediate after intervention
COVID-19 vaccination attitude
COVID-19 vaccination intention
COVID-19 vaccine belief

Trial Safety

Trial Design

6 Treatment Groups

No Control Group
Centralized Networks of Diverse Populations

This trial requires 1920 total participants across 6 different treatment groups

This trial involves 6 different treatments. Independent Control is the primary treatment being studied. Participants will be divided into 6 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Centralized Networks of Diverse Populations
Behavioral
Centralized networks have a small number of influential individuals, called "hubs," with connections to most other people. Centralized networks characterize situations in which most or all individuals are connected to, and seek advice from, a few well-connected "influencers." Each network is consisted of 40 individual participants. All network participants in this condition have very different baseline demographic characteristics, attitudes, or behavioral choices.
Independent Control of Homogeneous Populations
Behavioral
Independent control condition does not have online networks. Participants in this condition are not put into online networks. Participants only respond to questions by themselves. All participants in this condition share similar baseline demographic characteristics, attitudes, or behavioral choices.
Egalitarian Networks of Homogeneous Populations
Behavioral
Egalitarian networks are characterized by equal connectivity for all participants in an online network for information exchange. Each network is consisted of 40 individual participants. All network participants in this condition share similar baseline demographic characteristics, attitudes, or behavioral choices.
Centralized Networks of Homogeneous Populations
Behavioral
Centralized networks have a small number of influential individuals, called "hubs," with connections to most other people. Centralized networks characterize situations in which most or all individuals are connected to, and seek advice from, a few well-connected "influencers." Each network is consisted of 40 individual participants. All network participants in this condition share similar baseline demographic characteristics, attitudes, or behavioral choices.
Independent Control of Diverse Populations
Behavioral
Independent control condition does not have online networks. Participants in this condition are not put into online networks. Participants only respond to questions by themselves. All participants in this condition have very different baseline demographic characteristics, attitudes, or behavioral choices.
Egalitarian Networks of Diverse Populations
Behavioral
Egalitarian networks are characterized by equal connectivity for all participants in an online network for information exchange. Each network is consisted of 40 individual participants. All network participants in this condition have very different baseline demographic characteristics, attitudes, or behavioral choices.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: immediate after intervention
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly immediate after intervention for reporting.

Who is running the study

Principal Investigator
D. C.
Prof. Damon Centola, PhD
University of Pennsylvania

Closest Location

Annenberg School for Communication - Philadelphia, PA

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 3 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Having internet access
Aged 18 and above
Living in the United States

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are common treatments for covid-19?

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Treatment is primarily based on patient diagnosis when they are treated in hospital. It is common for people to receive medications for pain, cough and flu.

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What are the signs of covid-19?

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  • Symptoms of covid-19 are similar to other respiratory infections and in general are mild.\n- Symptoms are not persistent or specific to viral infection.\n- The symptoms reported in this study are not a reliable guide for prioritisation of hospital admissions or resource allocation.\n- In the absence of clinical evidence or other investigation, people with mild symptoms do not require hospital admission.\n- The severity of symptoms is also highly variable from-patient-to-patient, even from room-to-room.
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What is covid-19?

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There is a pandemic happening in South India. The prevalence of COPD remains high. The virus has been identified from the samples in Delhi. The case was a man who never travelled outside India. He had no family history of being infected. There is a history of two other previous cases of Covid-19 in the same village. There are no cases reported in the current local or national data at this stage. The National Institute of Virology Delhi confirms its presence in an animal sample. A total of 14 suspected cases are suspected.

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What causes covid-19?

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Covid-19 is a viral disease caused by a strain of virus that is distinct to but closely related to SARS-CoV-1. Although the full cause of the increased mortality rate is not understood, several factors, including increased morbidity, greater age at onset of symptoms, more prominent symptoms, greater illness severity, and higher levels of the disease's virulence factor, SARS-CoV-1 protease inhibitor, have been suggested. The role of immune suppression is not known. A global pandemic will lead to a large number of cases with high levels of virus shedding, with a possibility of SARS-CoV-2 spreading efficiently between individuals.

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Can covid-19 be cured?

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It could be cured from most infections and should be considered. There is no current evidence or indication for using a vaccine to cure the disease.

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How many people get covid-19 a year in the United States?

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In 2019, the US reported on 1.7 million hospitalisations, 885,000 deaths, and 19.2 million total infections. More than 2.5 million Americans have been infected with the COVID-19 virus that causes the disease, with 948,000 hospitalisations and 393,500 deaths; however, the true numbers are likely higher. As of July 31, 2,800,000 Americans have been diagnosed with COVID-19, with more than 70,000 cases and 2,000 deaths; the number is expected to rise. The number of people now with disease has dropped significantly within 10 days of a decline in new hospitalisations, and the number of deaths has also declined.

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How does independent control work?

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With a high-quality quality control approach and proper randomization at every step, this study demonstrates that independent control work is feasible in complex, multicenter clinical trials, providing both a powerful proof of concept for improved data quality with independent data analysis and a strong foundation for more widespread use of this approach in the field of clinical research.

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What does independent control usually treat?

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Data from a recent study of this study suggest that independent control may not be a valid end point for trials of influenza treatment. The validity of the term independent control for end points related to influenza treatment requires re-examination.

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What are the common side effects of independent control?

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The findings are consistent with the view that independent control can yield a low degree of placebo response in clinical trials for both primary and secondary outcomes, even when the control treatment is carefully designed. The main reasons for placebo response are high uncertainty about the real control treatment effect, and lack of power due to a low sample size. Data from a recent study have broad implications for clinical trial methodology and may have implications for both independent treatment and independent blinded trials in general.

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How serious can covid-19 be?

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Covid-19 can pose a major health threat to many countries. In view of its high fatality and morbidity, it is worthwhile to maintain a cautious, cautious approach in the face of the pandemic, and to strengthen the nation's preventive, prevention and response systems to reduce the transmission risk to humans and animals, such as to domestic and wild animals. This article aims to discuss the clinical presentation, risk stratification of infected individuals in the context of other diseases and to recommend the appropriate measures that should be taken, including the control of the virus and appropriate use of antimicrobial therapies according to the clinical presentations.

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What are the latest developments in independent control for therapeutic use?

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The rapid pace of technology and development has introduced new tools and technology for independent control of the effects of a therapy. These new strategies provide independent control and are useful for all new techniques requiring independent control for therapeutic use.

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What is the average age someone gets covid-19?

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It is estimated that the mean age of onset is 49.3 years old with women’s median age of onset being 55.6 and men’s median age of onset being 53 years old. The median length of an infected person's infectious period is 7 days but it could be up to 16 days.

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