Phenylephrine vs Eyelid Taping for Drooping Eyelid
What You Need to Know Before You Apply
What is the purpose of this trial?
This research study aims to compare whether Phenylephrine 2.5% ophthalmic eye drop solution can serve as a better indicator of the effect of a drooping upper eyelid (ptosis) by covering part of the upper portion of the field of vision as compared to traditional use of tape to lift up the upper eyelid in the evaluation of patients for surgical upper eyelid repair.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are taking certain drugs that should not be used with phenylephrine, like Ergot Derivatives, Iobenguane Radiopharmaceutical Products, Kratom, Lisuride, or Monoamine Oxidase Inhibitors.
Is phenylephrine safe for use in humans?
Phenylephrine is generally considered safe with few eye-related side effects, but it can cause serious heart-related issues like high blood pressure and stroke, especially in people with heart disease or high blood pressure. A lower concentration (2.5%) is recommended for eye exams and use in infants and the elderly, while a higher concentration (10%) should be used cautiously.12345
How does the drug phenylephrine differ from other treatments for drooping eyelid?
What data supports the effectiveness of the treatment for drooping eyelid?
Who Is on the Research Team?
Sara T Wester, MD
Principal Investigator
University of Miami
Are You a Good Fit for This Trial?
Adults aged 18-90 with drooping eyelids (ptosis) who are evaluating surgery for this condition can join. They must understand the study, be able to do a visual field test, and not have allergies to phenylephrine eye drops. People taking certain drugs like Ergot derivatives or with specific heart conditions cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo superior visual field testing with eyelid taping and Phenylephrine 2.5% ophthalmic solution
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Eyelid Tape
- Phenylephrine Ophthalmic
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Miami
Lead Sponsor