cryoanalgesia for Pain, Postoperative

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
AHN Allegheny General Hospital, Pittsburgh, PA
Pain, Postoperative+1 More
cryoanalgesia - Device
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This is a research study designed to test whether a treatment called Intercostal Nerve Cryotherapy is an effective way to help control post-surgical pain for patients undergoing minimally invasive pulmonary resection. There are two treatment groups in this study, a cryotherapy group and control group. Cryotherapy is a method of controlling pain by freezing nerves between the ribs that would transmit pain impulses to the brain.

Eligible Conditions

  • Pain, Postoperative
  • Cryotherapy Effect

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

2 Primary · 6 Secondary · Reporting Duration: through 1 year

Month 3
pain control
total morphine equivalent dose of narcotics
Year 1
Presence of neuropathy in the surgical site
through 1 year
pulmonary complications
Day 14
Hospital length of stay
Incentive Spirometer Volume
Pain control
Total morphine dose

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Standard of care pain control
1 of 2
Cryoanalgesia with standard of care pain control
1 of 2
Active Control
Experimental Treatment

100 Total Participants · 2 Treatment Groups

Primary Treatment: cryoanalgesia · No Placebo Group · N/A

Cryoanalgesia with standard of care pain controlExperimental Group · 2 Interventions: cryoanalgesia, Standard of Care Pain Control · Intervention Types: Device, Other
Standard of care pain control
Other
ActiveComparator Group · 1 Intervention: Standard of Care Pain Control · Intervention Types: Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: through 1 year
Closest Location: AHN Allegheny General Hospital · Pittsburgh, PA
Photo of Pittsburgh 1Photo of Pittsburgh 2Photo of Pittsburgh 3
N/AFirst Recorded Clinical Trial
1 TrialsResearching Pain, Postoperative
0 CompletedClinical Trials

Who is running the clinical trial?

AtriCure, Inc.Industry Sponsor
38 Previous Clinical Trials
17,341 Total Patients Enrolled
2 Trials studying Pain, Postoperative
1,040 Patients Enrolled for Pain, Postoperative
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)Lead Sponsor
37 Previous Clinical Trials
3,773 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 3 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have performance status 1 or 2.
Patients 18 years and older.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.