Clinical Trials in California

View paid research studies that are recruiting in California. Filter by distance, duration, and inclusion criteria to find clinical trials that pay well for your time.

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This study is evaluating whether a drug called KIN-2787 is safe and effective for people with advanced or metastatic cancer.

This study is evaluating whether a drug called XYWAV may be effective in treating narcolepsy.

Phase 1b/Phase 2 Umbrella Study; open-label, multi-center, parallel group study. Sasanlimab (a PD-1 antagonist monoclonal antibody) will be combined with a different targeted therapy in each sub-study. Phase1b of each sub-study will evaluate the safety of the combination and select the do…

This study is evaluating whether a combination of two drugs may help treat patients with advanced melanoma.

This study is evaluating whether a gene therapy may be effective for individuals with mucopolysaccharidosis II.

This study is evaluating whether a single injection of a drug may help treat AMD.

This study is evaluating whether a drug may help treat macular degeneration.

This study is evaluating whether light therapy may help improve sleep in individuals with Parkinson's Disease.

Questionnaire Administration

This study is evaluating whether a combination of chemotherapy and immunotherapy may be more effective than chemotherapy alone in treating endometrial cancer.

This study is evaluating whether a combination of chemotherapy, bevacizumab, and atezolizumab may help treat colorectal cancer.

Noninvasive Peripheral Nerve Stimulation (NPNS)

This study is evaluating whether a non-invasive nerve stimulation device may help reduce the amount of opioids needed to treat restless leg syndrome.

This study is evaluating whether a combination of two drugs may help treat prostate cancer.

casirivimab+imdevimab combination therapy

Phase 1 To evaluate the safety and tolerability of REGN10933+REGN10987 compared to placebo To evaluate the virologic efficacy of REGN10933+REGN10987 compared to placebo in reducing viral load of SARS-CoV-2 Phase 2 • To evaluate the virologic efficacy of REGN10933+REGN10987 compared to p…

This study is evaluating whether a drug may help treat atopic dermatitis.

This study is evaluating whether a type of white blood cell called T-cells may help treat multiple myeloma.

This study is evaluating whether radiation therapy with or without olaparib may help treat inflammatory breast cancer.

This study is evaluating whether cisplatin and combination chemotherapy may help treat children and young adults with hepatoblastoma or hepatocellular carcinoma.

This study is evaluating whether a drug may help treat chronic myelomonocytic leukemia or myelofibrosis.

This study is evaluating whether a drug called crizotinib may help treat patients with non-small cell lung cancer.

Gemcitabine (gem) (Cohort A and B)

This study is evaluating whether a combination of chemotherapy and immunotherapy may help treat pancreatic cancer.

More than Muscles (MTM)

This study is evaluating whether a novel program may help reduce eating disorders in males.

This study is evaluating whether a drug may help treat prurigo nodularis.

This study is evaluating whether a drug may help treat tumors with a specific genetic mutation.

Phase III, multicenter, randomized study with two arms (1:1 ratio) enrolling patients with AML relapsed/refractory after 2, 3, or 4 prior induction regimens: Experimental arm: DFP-10917 14-day continuous intravenous (IV) infusion at a dose of 6 mg/m²/day followed by a 14-day resting perio…

This study is evaluating whether a drug may help treat Crohn's disease.

This study is evaluating whether a type of white blood cell called a monoclonal antibody may help treat leukoplakia.

This study is evaluating whether a drug may help treat irritable bowel syndrome in children.

This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.…

Telisotuzumab Vedotin

This study is evaluating whether telisotuzumab vedotin is better than docetaxel for people with NSCLC.

Fetoscopic Endoluminal Tracheal Occlusion Surgery

This study is evaluating whether a new procedure may help improve lung growth for babies with severe congenital diaphragmatic hernia.

This study is evaluating whether a drug may help treat cancer.

Primary Objective: To determine whether Amcenestrant (SAR439859) in combination with palbociclib improvesprogression free survival (PFS) when compared with letrozole in combination with palbociclib in participants with ER+, HER2- advanced breast cancer who have not received any prior syst…

This study is evaluating whether a combination of drugs may be more effective than standard chemotherapy in treating patients with non-small cell lung cancer.

This study is evaluating whether a drug may help improve sleep quality for individuals who are caring for a loved one with Alzheimer's disease.

sumatriptan nasal powder

This study is evaluating whether a nasal spray may help treat migraines in adolescents.

This study is evaluating whether a combination of two drugs may help treat children with cancer.

Intensity-Modulated Radiation Therapy

This study is evaluating whether radiation therapy with or without cisplatin is more effective in treating patients with squamous cell carcinoma of the head and neck.

Phonak Lyric self-replacement procedure

This study is designed to investigate the effectiveness and safety of the Phonak Lyric self-replacement procedure, as compared to the HCP-replacement procedure.

This study compares insulin icodec (a new insulin taken once a week) to insulin degludec (an insulin taken once daily which is already available on the market) in people with type 2 diabetes. The study will look at how well insulin icodec taken weekly controls blood sugar compared to insu…

CMP-001-010 is a Phase 2 study of CMP-001 intratumoral (IT) and nivolumab intravenous (IV) administered to participants with refractory unresectable or metastatic melanoma. The primary objective of the study is to determine confirmed objective response with CMP-001 in combination with niv…

LVgp120duoCAR-T cells, low dose

This study is evaluating whether a new type of T cell therapy may help individuals with HIV.

Bempegaldesleukin

Washington, United States

Washington, United States

Any Age

All Sexes

This study is evaluating whether a combination of two drugs may help treat melanoma.

Educational Intervention

This study is evaluating whether a support program may help breast cancer patients take their medication correctly.

The purpose of this clinical study is to confirm the utility of chemosensitivity (ChemoID) tumor testing on cancer stem cells as a predictor of clinical response in recurrent platinum resistant epithelial ovarian cancer (EOC), fallopian tube, or primary peritoneal cancer. Population studi…

This study is evaluating whether a drug may help treat solid tumors.

This is a Phase Ib/II, open-label, multicenter, randomized umbrella study evaluating the efficacy and safety of multiple immunotherapy-based treatment combinations in patients with metastatic or inoperable locally advanced TNBC. The study will be performed in two stages. During Stage 1, t…

Study BP43445 is a phase II, multicenter, randomized, double-masked, active comparator-controlled study to investigate the efficacy, safety, tolerability, pharmacokinetics, and pharmacodynamics of RO7200220 administered intravitreally in participants with diabetic macular edema. Only one e…

This study is evaluating whether a drug called KVD824 can prevent attacks of hereditary angioedema.

The major objective is to demonstrate the safety and efficacy of ANG-3070 in patients with primary glomerular disease and persistent proteinuria.

QUIT Intervention (doctor brief advice, video doctor, health coaching sessions at 2- and 6-weeks)

The QUIT-Mobile study proposes to use mobile phone self-monitoring and feedback to enhance and sustain over 12-months the impacts of the Quit Using Drugs Intervention Trial (QUIT), an effective screening and brief intervention (SBI) previously successful in reducing risky drug use (i.e., m…

The main objective of this study is to evaluate the tumor objective response rate (ORR) assessed by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 criteria in participants who receive sotorasib at either 960 mg daily or 240 mg daily whose tumors are programmed death-ligand 1 (PD…

Participants in this study will have diffuse large B-cell lymphoma (DLBCL) that has come back or not gotten better with treatment. The trial will study whether brentuximab vedotin plus two drugs works better to treat this type of cancer than the two drugs alone. Participants will be rando…

Bardoxolone methyl oral capsule

This study is evaluating whether a drug may help treat polycystic kidney disease.

This study is evaluating whether a combination of two drugs may help treat liver cancer.

This study is evaluating whether a new type of heart valve may help patients with a failing heart valve.

This study is evaluating whether a drug may help increase appetite in patients with advanced cancer.

This study is evaluating whether a combination of drugs may help treat breast cancer.

Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in primary progressive multiple sclerosis (PPMS) Secondary Objectives: To evaluate efficacy of SAR442168 compared to placebo on clinical endpoints, magnetic resonance imaging…

This study is evaluating whether a combination of two drugs may help treat melanoma.

Injection into olfactory cleft

This study is evaluating whether platelet-rich plasma can improve olfactory function in people with olfactory dysfunction.

Directional Deep Brain Stimulation

This study is evaluating whether deep brain stimulation (DBS) can be used to treat depression.

This study is evaluating whether a combination of two drugs may be more effective than a combination of two other drugs in treating colorectal cancer.

This study is evaluating whether a combination of chemotherapy drugs may help treat neuroendocrine carcinoma.

Tasimelteon Oral Capsule, Tasimelteon Liquid Suspension

This is a multicenter, open-label study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon in treating sleep disturbances in pediatric and adult participants with ASD.

This study is evaluating whether a new drug can improve the survival of people with breast cancer.

This study is evaluating whether pemigatinib is safe and tolerable in people with advanced cancer.

To demonstrate that the RNS System is safe and effective as an adjunctive therapy in individuals age 12 through 17 years with medically refractory partial onset epilepsy.

NeoTCR-P1 adoptive cell therapy

This study is evaluating whether a type of white blood cell called T-cells may help treat solid tumors.

This study is evaluating whether a drug may help treat multiple myeloma.

This study is evaluating whether a combination of chemotherapy and immunotherapy may help treat ovarian, fallopian tube, or primary peritoneal cancer.

This study is evaluating whether a drug called tasimelteon can improve sleep in people with Smith-Magenis Syndrome.

Vinblastine

Washington, United States

Washington, United States

< 65

All Sexes

This study is evaluating whether a new treatment for Langerhans Cell Histiocytosis is safe and effective.

sleep education program

This study is evaluating whether a telehealth intervention can improve symptoms of depression, anxiety, and sleep in people with Alzheimer's disease.

This study is evaluating whether a new drug called selpercatinib can be given to people with cancer.

GSK3511294 (Depemokimab)

This study is evaluating whether switching participants who have benefitted from mepolizumab or benralizumab to GSK3511294 is non-inferior to maintaining current

This study is evaluating whether a drug combination may help improve lung function in individuals with cystic fibrosis.

This study is evaluating whether a one-time treatment with a gene therapy may help treat wet age-related macular degeneration.

This study is evaluating whether a drug called evobrutinib may help treat multiple sclerosis.

This study is evaluating whether a combination of two drugs may help patients with multiple myeloma.

This study is evaluating whether a combination of drugs may help treat lung cancer.

JCAR017 (lisocabtagene maraleucel) + ibrutinib

This study is evaluating whether a new type of white blood cell may help treat certain types of leukemia.

This is a dose finding study designed to evaluate the efficacy, safety, and pharmacokinetics of danicopan in participants with GA secondary to AMD. The study consists of a Screening Period of up to 4 weeks, a 104-week masked Treatment Period, followed by an Open-label Extension (OLE) Perio…