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Clinical Trials in California
View paid research studies that are recruiting in California. Filter by distance, duration, and inclusion criteria to find clinical trials that pay well for your time.
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KIN-2787
Los Angeles, CA
18+
All Sexes
Phase 1
Recruiting
Class I
Los Angeles, CA
18+
All Sexes
This study is evaluating whether a drug called KIN-2787 is safe and effective for people with advanced or metastatic cancer.
JZP-258
Los Angeles, CA
18+
All Sexes
Phase 4
Recruiting
Los Angeles, CA
18+
All Sexes
This study is evaluating whether a drug called XYWAV may be effective in treating narcolepsy.
Sasanlimab
Los Angeles, CA
18+
All Sexes
Phase 1 & 2
Recruiting
Locally Advanced
Los Angeles, CA
18+
All Sexes
Phase 1b/Phase 2 Umbrella Study; open-label, multi-center, parallel group study. Sasanlimab (a PD-1 antagonist monoclonal antibody) will be combined with a different targeted therapy in each sub-study. Phase1b of each sub-study will evaluate the safety of the combination and select the do…
PVSRIPO
Orange, CA
18+
All Sexes
Phase 2
Locally Advanced
Orange, CA
18+
All Sexes
This study is evaluating whether a combination of two drugs may help treat patients with advanced melanoma.
RGX-121
Oakland, CA
< 18
Male
Phase 1 & 2
Recruiting
Oakland, CA
< 18
Male
This study is evaluating whether a gene therapy may be effective for individuals with mucopolysaccharidosis II.
GT005: High Dose
Lenexa, KS
18+
All Sexes
Phase 2
Recruiting
Stage I
Lenexa, KS
18+
All Sexes
This study is evaluating whether a single injection of a drug may help treat AMD.
Faricimab
Chesterfield, MO
18+
All Sexes
Phase 3
Chesterfield, MO
18+
All Sexes
This study is evaluating whether a drug may help treat macular degeneration.
SunRay Light Boxes
Salt Lake City, UT
18+
All Sexes
Recruiting
Stage II
Salt Lake City, UT
18+
All Sexes
This study is evaluating whether light therapy may help improve sleep in individuals with Parkinson's Disease.
Questionnaire Administration
Redding, CA
18+
Female
Phase 3
Recruiting
Locally Advanced
Redding, CA
18+
Female
This study is evaluating whether a combination of chemotherapy and immunotherapy may be more effective than chemotherapy alone in treating endometrial cancer.
Bevacizumab
Orange, CA
18+
All Sexes
Phase 3
Recruiting
Metastatic
Orange, CA
18+
All Sexes
This study is evaluating whether a combination of chemotherapy, bevacizumab, and atezolizumab may help treat colorectal cancer.
Noninvasive Peripheral Nerve Stimulation (NPNS)
Downey, CA
18+
All Sexes
Recruiting
Downey, CA
18+
All Sexes
This study is evaluating whether a non-invasive nerve stimulation device may help reduce the amount of opioids needed to treat restless leg syndrome.
Capivasertib
La Jolla, CA
18+
Male
Phase 3
Recruiting
Metastatic
La Jolla, CA
18+
Male
This study is evaluating whether a combination of two drugs may help treat prostate cancer.
casirivimab+imdevimab combination therapy
Jackson, MS
Any Age
All Sexes
Phase 3
Jackson, MS
Any Age
All Sexes
Phase 1 To evaluate the safety and tolerability of REGN10933+REGN10987 compared to placebo To evaluate the virologic efficacy of REGN10933+REGN10987 compared to placebo in reducing viral load of SARS-CoV-2 Phase 2 • To evaluate the virologic efficacy of REGN10933+REGN10987 compared to p…
Lebrikizumab
Newport Beach, CA
Any Age
All Sexes
Phase 3
Recruiting
Newport Beach, CA
Any Age
All Sexes
This study is evaluating whether a drug may help treat atopic dermatitis.
CT053
Houston, TX
18+
All Sexes
Phase 1 & 2
Recruiting
1 Prior Treatment
Houston, TX
18+
All Sexes
This study is evaluating whether a type of white blood cell called T-cells may help treat multiple myeloma.
Radiation Therapy
Carmel, IN
18+
All Sexes
Phase 2
Recruiting
Grade II
Carmel, IN
18+
All Sexes
This study is evaluating whether radiation therapy with or without olaparib may help treat inflammatory breast cancer.
Cisplatin
Aurora, CO
< 65
All Sexes
Phase 2 & 3
Recruiting
High Risk
Aurora, CO
< 65
All Sexes
This study is evaluating whether cisplatin and combination chemotherapy may help treat children and young adults with hepatoblastoma or hepatocellular carcinoma.
SL-401
Los Angeles, CA
18+
All Sexes
Phase 2
Recruiting
Stage II
Los Angeles, CA
18+
All Sexes
This study is evaluating whether a drug may help treat chronic myelomonocytic leukemia or myelofibrosis.
Crizotinib
Livonia, MI
18+
All Sexes
Phase 3
Waitlist Available
Locally Advanced
Livonia, MI
18+
All Sexes
This study is evaluating whether a drug called crizotinib may help treat patients with non-small cell lung cancer.
Gemcitabine (gem) (Cohort A and B)
San Francisco, CA
18+
All Sexes
Phase 1
Recruiting
Locally Advanced
San Francisco, CA
18+
All Sexes
This study is evaluating whether a combination of chemotherapy and immunotherapy may help treat pancreatic cancer.
More than Muscles (MTM)
San Diego, CA
18 - 65
Male
San Diego, CA
18 - 65
Male
This study is evaluating whether a novel program may help reduce eating disorders in males.
Nemolizumab 30 mg
Sacramento, CA
18+
All Sexes
Phase 3
Recruiting
Sacramento, CA
18+
All Sexes
This study is evaluating whether a drug may help treat prurigo nodularis.
ASTX295
Los Angeles, CA
18+
All Sexes
Phase 1 & 2
Recruiting
Locally Advanced
Los Angeles, CA
18+
All Sexes
This study is evaluating whether a drug may help treat tumors with a specific genetic mutation.
DFP-10917
New Orleans, LA
18+
All Sexes
Phase 3
Recruiting
High Risk
New Orleans, LA
18+
All Sexes
Phase III, multicenter, randomized study with two arms (1:1 ratio) enrolling patients with AML relapsed/refractory after 2, 3, or 4 prior induction regimens: Experimental arm: DFP-10917 14-day continuous intravenous (IV) infusion at a dose of 6 mg/m²/day followed by a 14-day resting perio…
Mirikizumab
Jacksonville, FL
Any Age
All Sexes
Phase 3
Recruiting
Jacksonville, FL
Any Age
All Sexes
This study is evaluating whether a drug may help treat Crohn's disease.
Pembrolizumab
Los Angeles, CA
18+
All Sexes
Phase 2
Recruiting
Metastatic
Los Angeles, CA
18+
All Sexes
This study is evaluating whether a type of white blood cell called a monoclonal antibody may help treat leukoplakia.
Eluxadoline
Cleveland, OH
< 18
All Sexes
Phase 2
Recruiting
Cleveland, OH
< 18
All Sexes
This study is evaluating whether a drug may help treat irritable bowel syndrome in children.
Nivolumab
Riverside, CA
18+
All Sexes
Phase 2
Recruiting
Grade I
Riverside, CA
18+
All Sexes
This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.…
Telisotuzumab Vedotin
Brooklyn, NY
18+
All Sexes
Phase 3
Recruiting
Locally Advanced
Brooklyn, NY
18+
All Sexes
This study is evaluating whether telisotuzumab vedotin is better than docetaxel for people with NSCLC.
Fetoscopic Endoluminal Tracheal Occlusion Surgery
San Francisco, CA
18+
Female
Recruiting
San Francisco, CA
18+
Female
This study is evaluating whether a new procedure may help improve lung growth for babies with severe congenital diaphragmatic hernia.
INCB106385
West Hollywood, CA
18+
All Sexes
Phase 1
Recruiting
Locally Advanced
West Hollywood, CA
18+
All Sexes
This study is evaluating whether a drug may help treat cancer.
SAR439859
San Francisco, CA
18+
All Sexes
Phase 3
Locally Advanced
San Francisco, CA
18+
All Sexes
Primary Objective: To determine whether Amcenestrant (SAR439859) in combination with palbociclib improvesprogression free survival (PFS) when compared with letrozole in combination with palbociclib in participants with ER+, HER2- advanced breast cancer who have not received any prior syst…
Nivolumab
Burbank, CA
18+
All Sexes
Phase 2
Recruiting
Class II
Burbank, CA
18+
All Sexes
This study is evaluating whether a combination of drugs may be more effective than standard chemotherapy in treating patients with non-small cell lung cancer.
MAP-I
Los Angeles, CA
18+
All Sexes
Recruiting
Los Angeles, CA
18+
All Sexes
This study is evaluating whether a drug may help improve sleep quality for individuals who are caring for a loved one with Alzheimer's disease.
sumatriptan nasal powder
Anaheim, CA
< 18
All Sexes
Phase 3
Recruiting
Anaheim, CA
< 18
All Sexes
This study is evaluating whether a nasal spray may help treat migraines in adolescents.
Lenvatinib
Los Angeles, CA
< 65
All Sexes
Phase 1 & 2
Metastatic
Los Angeles, CA
< 65
All Sexes
This study is evaluating whether a combination of two drugs may help treat children with cancer.
Intensity-Modulated Radiation Therapy
Durango, CO
18+
All Sexes
Phase 2
Recruiting
Metastatic
Durango, CO
18+
All Sexes
This study is evaluating whether radiation therapy with or without cisplatin is more effective in treating patients with squamous cell carcinoma of the head and neck.
Phonak Lyric self-replacement procedure
Houston, TX
18+
All Sexes
Recruiting
Houston, TX
18+
All Sexes
This study is designed to investigate the effectiveness and safety of the Phonak Lyric self-replacement procedure, as compared to the HCP-replacement procedure.
Insulin icodec
Concord, Canada
18+
All Sexes
Phase 3
Concord, Canada
18+
All Sexes
This study compares insulin icodec (a new insulin taken once a week) to insulin degludec (an insulin taken once daily which is already available on the market) in people with type 2 diabetes. The study will look at how well insulin icodec taken weekly controls blood sugar compared to insu…
CMP-001
Duarte, CA
18+
All Sexes
Phase 2
Recruiting
Locally Advanced
Duarte, CA
18+
All Sexes
CMP-001-010 is a Phase 2 study of CMP-001 intratumoral (IT) and nivolumab intravenous (IV) administered to participants with refractory unresectable or metastatic melanoma. The primary objective of the study is to determine confirmed objective response with CMP-001 in combination with niv…
LVgp120duoCAR-T cells, low dose
Sacramento, CA
18+
All Sexes
Phase 1 & 2
Recruiting
Sacramento, CA
18+
All Sexes
This study is evaluating whether a new type of T cell therapy may help individuals with HIV.
Bempegaldesleukin
Washington, United States
Any Age
All Sexes
Phase 3
High Risk
Washington, United States
Any Age
All Sexes
This study is evaluating whether a combination of two drugs may help treat melanoma.
Educational Intervention
San Rafael, CA
18+
Female
Phase 3
Recruiting
Stage I
San Rafael, CA
18+
Female
This study is evaluating whether a support program may help breast cancer patients take their medication correctly.
ChemoID Assay
Los Angeles, CA
18+
Female
Phase 3
Recruiting
Metastatic
Los Angeles, CA
18+
Female
The purpose of this clinical study is to confirm the utility of chemosensitivity (ChemoID) tumor testing on cancer stem cells as a predictor of clinical response in recurrent platinum resistant epithelial ovarian cancer (EOC), fallopian tube, or primary peritoneal cancer. Population studi…
rebastinib
Oklahoma City, OK
18+
All Sexes
Phase 1 & 2
Locally Advanced
Oklahoma City, OK
18+
All Sexes
This study is evaluating whether a drug may help treat solid tumors.
Nab-Paclitaxel
Stanford, CA
18+
All Sexes
Phase 1 & 2
Recruiting
Locally Advanced
Stanford, CA
18+
All Sexes
This is a Phase Ib/II, open-label, multicenter, randomized umbrella study evaluating the efficacy and safety of multiple immunotherapy-based treatment combinations in patients with metastatic or inoperable locally advanced TNBC. The study will be performed in two stages. During Stage 1, t…
RO7200220
Torrance, CA
18+
All Sexes
Phase 2
Recruiting
Torrance, CA
18+
All Sexes
Study BP43445 is a phase II, multicenter, randomized, double-masked, active comparator-controlled study to investigate the efficacy, safety, tolerability, pharmacokinetics, and pharmacodynamics of RO7200220 administered intravitreally in participants with diabetic macular edema. Only one e…
KVD824
La Jolla, CA
18+
All Sexes
Phase 2
Recruiting
La Jolla, CA
18+
All Sexes
This study is evaluating whether a drug called KVD824 can prevent attacks of hereditary angioedema.
ANG-3070
Boston, MA
18+
All Sexes
Phase 2
Recruiting
Boston, MA
18+
All Sexes
The major objective is to demonstrate the safety and efficacy of ANG-3070 in patients with primary glomerular disease and persistent proteinuria.
QUIT Intervention (doctor brief advice, video doctor, health coaching sessions at 2- and 6-weeks)
Long Beach, CA
18+
All Sexes
Recruiting
Long Beach, CA
18+
All Sexes
The QUIT-Mobile study proposes to use mobile phone self-monitoring and feedback to enhance and sustain over 12-months the impacts of the Quit Using Drugs Intervention Trial (QUIT), an effective screening and brief intervention (SBI) previously successful in reducing risky drug use (i.e., m…
Sotorasib
Charleston, SC
18+
All Sexes
Phase 2
Recruiting
Metastatic
Charleston, SC
18+
All Sexes
The main objective of this study is to evaluate the tumor objective response rate (ORR) assessed by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 criteria in participants who receive sotorasib at either 960 mg daily or 240 mg daily whose tumors are programmed death-ligand 1 (PD…
Lenalidomide
Sacramento, CA
18+
All Sexes
Phase 3
Recruiting
1 Prior Treatment
Sacramento, CA
18+
All Sexes
Participants in this study will have diffuse large B-cell lymphoma (DLBCL) that has come back or not gotten better with treatment. The trial will study whether brentuximab vedotin plus two drugs works better to treat this type of cancer than the two drugs alone. Participants will be rando…
Bardoxolone methyl oral capsule
Downey, CA
Any Age
All Sexes
Phase 3
Recruiting
Downey, CA
Any Age
All Sexes
This study is evaluating whether a drug may help treat polycystic kidney disease.
Durvalumab
La Jolla, CA
18+
All Sexes
Phase 3
High Risk
La Jolla, CA
18+
All Sexes
This study is evaluating whether a combination of two drugs may help treat liver cancer.
Edwards SAPIEN 3 THV
Stanford, CA
Any Age
All Sexes
Recruiting
Stanford, CA
Any Age
All Sexes
This study is evaluating whether a new type of heart valve may help patients with a failing heart valve.
PF-06946860
Los Angeles, CA
18+
All Sexes
Phase 1
Locally Advanced
Los Angeles, CA
18+
All Sexes
This study is evaluating whether a drug may help increase appetite in patients with advanced cancer.
Abemaciclib
Pittsburgh, PA
18+
Female
Phase 1 & 2
Recruiting
Locally Advanced
Pittsburgh, PA
18+
Female
This study is evaluating whether a combination of drugs may help treat breast cancer.
Tolebrutinib
San Francisco, CA
18 - 65
All Sexes
Phase 3
Recruiting
San Francisco, CA
18 - 65
All Sexes
Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in primary progressive multiple sclerosis (PPMS) Secondary Objectives: To evaluate efficacy of SAR442168 compared to placebo on clinical endpoints, magnetic resonance imaging…
LXH254
Los Angeles, CA
Any Age
All Sexes
Phase 2
Recruiting
Metastatic
Los Angeles, CA
Any Age
All Sexes
This study is evaluating whether a combination of two drugs may help treat melanoma.
Injection into olfactory cleft
San Diego, CA
18+
All Sexes
San Diego, CA
18+
All Sexes
This study is evaluating whether platelet-rich plasma can improve olfactory function in people with olfactory dysfunction.
Directional Deep Brain Stimulation
Los Angeles, CA
18+
All Sexes
Recruiting
1 Prior Treatment
Los Angeles, CA
18+
All Sexes
This study is evaluating whether deep brain stimulation (DBS) can be used to treat depression.
Trastuzumab
Orland Park, IL
18+
All Sexes
Phase 2
Class III
Orland Park, IL
18+
All Sexes
This study is evaluating whether a combination of two drugs may be more effective than a combination of two other drugs in treating colorectal cancer.
Capecitabine
West Branch, MI
18+
All Sexes
Phase 2
Recruiting
Locally Advanced
West Branch, MI
18+
All Sexes
This study is evaluating whether a combination of chemotherapy drugs may help treat neuroendocrine carcinoma.
Tasimelteon Oral Capsule, Tasimelteon Liquid Suspension
San Leandro, CA
Any Age
All Sexes
Phase 3
Recruiting
San Leandro, CA
Any Age
All Sexes
This is a multicenter, open-label study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon in treating sleep disturbances in pediatric and adult participants with ASD.
Dato-DXd
San Francisco, CA
18+
All Sexes
Phase 3
Recruiting
Metastatic
San Francisco, CA
18+
All Sexes
This study is evaluating whether a new drug can improve the survival of people with breast cancer.
Pemigatinib
Santa Monica, CA
18+
All Sexes
Phase 2
Recruiting
Locally Advanced
Santa Monica, CA
18+
All Sexes
This study is evaluating whether pemigatinib is safe and tolerable in people with advanced cancer.
RNS System
Orange, CA
< 18
All Sexes
Recruiting
Orange, CA
< 18
All Sexes
To demonstrate that the RNS System is safe and effective as an adjunctive therapy in individuals age 12 through 17 years with medically refractory partial onset epilepsy.
NeoTCR-P1 adoptive cell therapy
Los Angeles, CA
18+
All Sexes
Phase 1
Metastatic
Los Angeles, CA
18+
All Sexes
This study is evaluating whether a type of white blood cell called T-cells may help treat solid tumors.
Daratumumab
Duarte, CA
18+
All Sexes
Phase 2
Recruiting
Duarte, CA
18+
All Sexes
This study is evaluating whether a drug may help treat multiple myeloma.
Bevacizumab
Caro, MI
18+
Female
Phase 2 & 3
Grade III
Caro, MI
18+
Female
This study is evaluating whether a combination of chemotherapy and immunotherapy may help treat ovarian, fallopian tube, or primary peritoneal cancer.
tasimelteon
Santa Monica, CA
Any Age
All Sexes
Phase 2 & 3
Waitlist Available
Santa Monica, CA
Any Age
All Sexes
This study is evaluating whether a drug called tasimelteon can improve sleep in people with Smith-Magenis Syndrome.
Vinblastine
Washington, United States
< 65
All Sexes
Phase 2 & 3
Recruiting
Newly Diagnosed
Washington, United States
< 65
All Sexes
This study is evaluating whether a new treatment for Langerhans Cell Histiocytosis is safe and effective.
sleep education program
Los Angeles, CA
18+
All Sexes
Recruiting
Los Angeles, CA
18+
All Sexes
This study is evaluating whether a telehealth intervention can improve symptoms of depression, anxiety, and sleep in people with Alzheimer's disease.
Selpercatinib
Anaheim, CA
18+
All Sexes
Phase 1
Recruiting
Anaheim, CA
18+
All Sexes
This study is evaluating whether a new drug called selpercatinib can be given to people with cancer.
GSK3511294 (Depemokimab)
Long Beach, CA
Any Age
All Sexes
Phase 3
Recruiting
Long Beach, CA
Any Age
All Sexes
This study is evaluating whether switching participants who have benefitted from mepolizumab or benralizumab to GSK3511294 is non-inferior to maintaining current
ALIS
Los Angeles, CA
18+
All Sexes
Phase 3
Recruiting
Los Angeles, CA
18+
All Sexes
This study is evaluating whether a drug combination may help improve lung function in individuals with cystic fibrosis.
RGX-314 Dose 3
Beverly Hills, CA
18+
All Sexes
Phase 2
Recruiting
Beverly Hills, CA
18+
All Sexes
This study is evaluating whether a one-time treatment with a gene therapy may help treat wet age-related macular degeneration.
Evobrutinib
Mobile, AL
18 - 65
All Sexes
Phase 3
1 Prior Treatment
Mobile, AL
18 - 65
All Sexes
This study is evaluating whether a drug called evobrutinib may help treat multiple sclerosis.
Daratumumab/rHuPH20
Richmond, IN
18+
All Sexes
Phase 3
Recruiting
Richmond, IN
18+
All Sexes
This study is evaluating whether a combination of two drugs may help patients with multiple myeloma.
Osimertinib
Santa Monica, CA
18+
All Sexes
Phase 2
Recruiting
Locally Advanced
Santa Monica, CA
18+
All Sexes
This study is evaluating whether a combination of drugs may help treat lung cancer.
JCAR017 (lisocabtagene maraleucel) + ibrutinib
Los Angeles, CA
18+
All Sexes
Phase 1 & 2
Recruiting
Grade I
Los Angeles, CA
18+
All Sexes
This study is evaluating whether a new type of white blood cell may help treat certain types of leukemia.
Danicopan
Waterford, CT
65+
All Sexes
Phase 2
Recruiting
Waterford, CT
65+
All Sexes
This is a dose finding study designed to evaluate the efficacy, safety, and pharmacokinetics of danicopan in participants with GA secondary to AMD. The study consists of a Screening Period of up to 4 weeks, a 104-week masked Treatment Period, followed by an Open-label Extension (OLE) Perio…