Tai Chi for Insomnia in Breast Cancer Survivors
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to help breast cancer survivors struggling with chronic insomnia by testing the effectiveness of Tai Chi Chih, a type of slow-moving meditation, in improving sleep quality. Participants will be compared with those receiving Cognitive Behavioral Therapy, a known treatment for insomnia. Women who have been cancer-free after early breast cancer treatment and experience sleep troubles at least three times a week for over six months might be a good fit.
As an unphased trial, this study provides a unique opportunity to explore alternative therapies for enhancing sleep quality.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications. However, if your insomnia is directly related to a medication that affects sleep or immune function, you may not be eligible to participate.
What prior data suggests that Tai Chi Chih is safe for breast cancer survivors with insomnia?
Research has shown that Tai Chi Chih is generally safe for breast cancer survivors. This gentle exercise can help improve sleep. Studies have found that Tai Chi Chih not only aids sleep but also reduces fatigue, making it a promising option for those struggling with sleep problems after cancer treatment. Reports of harmful side effects are rare, suggesting it is well-tolerated. Overall, Tai Chi Chih appears to be a safe and effective way to manage sleep issues in breast cancer survivors.12345
Why are researchers excited about this trial?
Tai Chi Chih is unique because it offers a holistic approach to managing insomnia in breast cancer survivors, focusing on gentle, mindful movements that promote relaxation and improve sleep quality. Unlike standard treatments like medication or cognitive behavioral therapy, Tai Chi Chih emphasizes physical and mental harmony, potentially reducing stress and enhancing overall well-being without the side effects often associated with pharmaceutical options. Researchers are excited about this method because it combines physical activity with meditation, offering a non-invasive, side-effect-free alternative to traditional insomnia treatments.
What evidence suggests that this trial's treatments could be effective for insomnia in breast cancer survivors?
Research has shown that Tai Chi Chih (TCC), which participants in this trial may receive, can help breast cancer survivors with sleep difficulties. Studies have found that TCC significantly improves sleep quality and duration. In one study, nearly half of the women who practiced Tai Chi or participated in cognitive behavioral therapy (CBT), another treatment option in this trial, experienced much better sleep after a year. Tai Chi also reduces inflammation, often linked to sleep problems in breast cancer survivors. Although more research is needed, early results suggest that Tai Chi Chih could effectively improve sleep for these individuals.12678
Who Is on the Research Team?
Michael Irwin, MD
Principal Investigator
University of California, Los Angeles
Are You a Good Fit for This Trial?
This trial is for postmenopausal women aged 30-70 who had early-stage breast cancer, have finished treatment, and are now struggling with chronic insomnia. They should experience sleep difficulties at least three nights a week for over six months and live close enough to attend sessions. Exclusions include those with certain medical conditions affecting sleep or immune function, obesity (BMI >35), smokers, cognitive impairment, other major psychiatric disorders or different sleep disorders.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Pre-treatment Assessment
Baseline assessment including all-night polysomnography and nocturnal sampling of proinflammatory cytokine activity and HRV tone
Treatment
Participants receive either Tai Chi Chih or Cognitive Behavioral Therapy
Mid-treatment Assessment
Midtreatment assessment with questionnaire ratings of sleep quality and a single morning sample of cytokine levels
Post-treatment Assessment
Post-treatment assessment including all-night polysomnography and nocturnal sampling of proinflammatory cytokine activity and HRV tone
3-month Follow-up
Assessment of sleep quality, mood, health functioning, and cytokine levels
12-month Follow-up
Assessment of sleep quality, mood, health functioning, and cytokine levels
What Are the Treatments Tested in This Trial?
Interventions
- Cognitive Behavioral Therapy
- Tai Chi Chih
Find a Clinic Near You
Who Is Running the Clinical Trial?
Jonsson Comprehensive Cancer Center
Lead Sponsor
National Center for Research Resources (NCRR)
Collaborator