Clinical TrialsClinical Trials in Florida
Reviewed by Michael Gill, B. Sc.
Image of DaVita Inglewood Dialysis in Inglewood, United States.
Phase-Based Progress Estimates
1
Effectiveness
1
Safety

PF-07321332 (nirmatrelvir)/ritonavir Participants With Severe Renal Impairment On Hemodialysisfor COVID19 (disease)

18+
All Sexes
The purpose of this study is to learn about the side effects (safety) of the study medicine PF-07321332 (nirmatrelvir)/ritonavir for the treatment of mild to moderate COVID-19 infection in adults with severe renal impairment. The study will also look at the amounts of study drug in your blood. There will be 24 participants in this study; 12 of them will have severe renal impairment and not be on hemodialysis and 12 of them will be on hemodialysis. All participants in this study will take PF-07321332 (nirmatrelvir)/ritonavir by mouth for 5 days. During this time, they will have to collect blood samples to measure the study drug levels in their blood. After taking the study drug for 5 days, the participants will have follow-up visits for about another 28 days for a total of about 34 days in the study. The study team will check how each participant is doing during regular visits at the study clinic.
Phase 1
Recruiting
DaVita Inglewood Dialysis (+36 Sites)Pfizer CT.gov Call CenterPfizer
25 Florida Clinical Trials Near Me
Top Cities for Florida Clinical Trials
Image of Miami in Florida.
Miami
228Active Trials
University of Miami Miller School of Medicine-Sylvester Cancer CenterTop Active Site
Image of Los Angeles in California.
Los Angeles
151Active Trials
Kaiser Permanente Los Angeles Medical CenterTop Active Site