Study Summary
This trial tests a new drug for adults with major depressive disorder, to see if it's safe and effective.
- Depression
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 1 Secondary · Reporting Duration: From baseline to week 14
Trial Safety
Safety Progress
Side Effects for
Trial Design
2 Treatment Groups
SEP-363856 & ADT (Antidepressant Therapy)
1 of 2
Placebo & ADT (Antidepressant Therapy)
1 of 2
Experimental Treatment
Non-Treatment Group
900 Total Participants · 2 Treatment Groups
Primary Treatment: SEP-363856 & ADT (Antidepressant Therapy) · Has Placebo Group · Phase 2 & 3
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18 - 65 · All Participants · 3 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Frequently Asked Questions
Are people with the required qualifications currently being sought for this research project?
"This particular clinical trial, as stated on clinicaltrials.gov, is no longer recruiting patients. The trial was originally posted on November 8th, 2020 and was last edited on November 2nd, 2020. There are, however, 2103 other studies that are actively recruiting patients." - Anonymous Online Contributor
If a patient is outside of the target age group, will they still be able to participate in this research?
"The age requirements for this particular clinical trial are between 18 to 65 years old. Out of the 1488 trials for patients over 65 and the 423 trials for patients under 18, this is the only one that they may be eligible for." - Anonymous Online Contributor
Who would be able to enroll and participate in this clinical trial?
"To be included in this study, which is investigating major depressive disorder, participants must be between 18-65 years old, have a primary diagnosis of MDD, and be in their current major depressive episode for 8 weeks to 2 years. Additionally, participants must have had an inadequate response to 1-3 antidepressant treatments in their current major depressive episode." - Anonymous Online Contributor