Decision-Making Support for Prostate Cancer Screening

(PSA Trial)

Age: 18+

Sex: Male

Trial Phase: Academic

Sponsor: Jonsson Comprehensive Cancer Center

Disqualifiers: Non-Latino, Age, Prostate problems, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 2

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to help Latino men make informed decisions about prostate cancer screening by increasing their knowledge of the benefits and risks. Participants will either join a small group intervention session for an interactive discussion or receive printed educational materials about prostate cancer. The trial seeks to determine if these methods improve understanding, encourage discussions with loved ones and doctors, and increase screening rates. Ideal participants are Latino men living in Los Angeles County who haven't had prostate cancer, a prostate biopsy, or a PSA test in the last year. As an unphased trial, this study offers participants the opportunity to contribute to valuable research that could enhance prostate cancer screening education for Latino men.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that this decision-making support intervention is safe?

Research has shown that educational sessions about prostate cancer are both helpful and safe. One study found that attendees significantly increased their knowledge about prostate cancer. Their participation in PSA (prostate-specific antigen) testing rose from 6.12% to 36.4% just three months after the sessions, indicating that more people felt informed and comfortable enough to get tested.

Another study demonstrated that these educational programs greatly improved understanding immediately after attendance. Participants felt more confident about their choices related to prostate cancer screening. Importantly, no reports of harm or negative effects emerged from attending these sessions, suggesting they are safe and well-tolerated by participants. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about this trial because it focuses on enhancing decision-making support for prostate cancer screening. Unlike traditional methods that rely solely on medical consultations, this trial explores the effectiveness of educational small group sessions and printed materials to empower patients with knowledge about prostate cancer. By providing tailored education, the trial aims to help individuals make more informed choices about their screening options. This approach could potentially lead to better patient outcomes by ensuring decisions are aligned with personal values and preferences.

What evidence suggests that this intervention is effective for increasing informed decision-making in prostate cancer screening?

Research has shown that educational sessions can significantly enhance understanding of prostate cancer. In this trial, participants in one arm will attend a small group educational session on prostate cancer. One study found that attendees of such sessions gained substantial knowledge about prostate cancer screening immediately afterward. Another study discovered that educational activities led to better decision-making, with more individuals engaging in shared decision-making and undergoing PSA (prostate-specific antigen) screenings. This indicates that group discussions and learning can effectively raise awareness and influence decisions about prostate cancer screening. These sessions aim to help individuals make informed health decisions. ^{1 2 3 5 6}

Who Is on the Research Team?

Roshan Bastani, PhD

Principal Investigator

University of California, Los Angeles

Are You a Good Fit for This Trial?

This trial is for Latino men aged 50-70 in Los Angeles who have never had prostate cancer or a PSA test in the last year, and do not currently have prostate issues like pain during urination. Men with previous prostate surgery, biopsy, or outside the age range are excluded.

Inclusion Criteria

I am a Latino man.

I do not have prostate inflammation.

I have never had prostate cancer.

Exclusion Criteria

Having had a prostate biopsy

I am either under 50 or over 70 years old.

Living outside of Los Angeles county

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants engage in an interactive multi-media presentation discussing prostate cancer, screening methods, and treatment. A facilitator guides the 1-hour discussion.

1 hour

1 visit (in-person)

Follow-up

Participants are followed up at 6 months via a telephone interview to assess knowledge and communication about prostate cancer.

6 months

1 visit (telephone)

What Are the Treatments Tested in This Trial?

Interventions

• Intervention Session
• Printed Material

Trial Overview The study tests if an interactive session discussing prostate cancer screening can improve decision-making among participants compared to just receiving printed material. The impact on knowledge and screening rates will be assessed through follow-ups.

How Is the Trial Designed?

Group I: 2 Experimental Treatment 1 Intervention

Printed material regarding general prostate cancer information provided.

Group II: 1 Experimental Treatment 1 Intervention

Educational small group session regarding prostate cancer

Who Is Running the Clinical Trial?

Jonsson Comprehensive Cancer Center

Lead Sponsor

Trials

373

Recruited

35,200+

National Cancer Institute (NCI)

Collaborator

Trials

14,080

Recruited

41,180,000+

Citations

1. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC4548640/

The impact of educational sessions provided on prostate ... Randomized trial examining the effect of two prostate cancer screening educational interventions on patient knowledge, preferences, and behaviors. J Gen ...

2. bmjopenquality.bmj.com bmjopenquality.bmj.com/content/14/4/e003423

PSAzing up patient care: a quality improvement project for ... Results SDM documentation improved significantly from 7.1% preintervention to 37.2% postintervention (p<0.001). PSA screening rates increased ...

3. bmccancer.biomedcentral.com bmccancer.biomedcentral.com/counter/pdf/10.1186/s12885-024-12044-9.pdf?utm_source=consensus

Effect of health belief model-based educational ... Results Participants' knowledge about prostate cancer screening improved significantly immediately after the program and this positive ...

4. sciencemediacentre.org sciencemediacentre.org/new-data-on-prostate-cancer-screening-outcomes/

new data on prostate cancer screening outcomes The research showed that for every 456 men who were offered prostate specific antigen (PSA) testing, one life was saved. However, the tests also ...

5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC9973384/

Testing a Prostate Cancer Educational Intervention in High ... The goal of this study was to test the impact of a targeted PCa educational intervention vs. a healthy lifestyle educational control intervention.

6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC5980833/

Effects of an Educational Program for Prostate Cancer ... Findings: The results showed that the intervention group's participation in PSA testing increased from 6.12% to 36.4% three months after the intervention.