PRP Clinical Trials 2023

What Are PRP Clinical Trials?

Platelet-rich plasma (PRP) uses a patient’s own blood cells to heal certain parts of the body. PRP therapy is administered by intravenous injections. PRP injections are prepared by taking a few tubes of a patient’s blood and running it through a centrifuge to concentrate the platelets by separating red blood cells.

These concentrated platelets are then injected directly into the injured part or area of the body. Ultrasonic imaging may be used to guide the injection. The introduction of pallets can stimulate growth factors and increase the number of reparative cells that the body produces.

PRP clinical trials can be used to significantly accelerate the healing process for various parts of the body, including rotator cuff tears, Achilles tendon ruptures, and other soft tissue injuries. A major benefit of PRP therapy is that it reduces the need for medications like opioids to combat inflammation.

Why Is PRP Being Studied Through Clinical Trials?

At the time of writing, there is fairly limited research on PRP therapy and many experts may not recommend its use. This is why more PRP clinical trials are needed to study its safety, feasibility and efficacy in the treatment of various diseases. More specifically, PRP therapy has gained notoriety for use in treating androgenic alopecia (male pattern baldness) and stimulating healthy hair growth in the beard area.

What Are The Types of Treatments Available For PRP?

There are different types of PRP treatment depending on platelet concentrates which are distinguished based on their fibrin architecture. These are known as pure PRP, leukocyte and PRP (L-PRP), and leukocyte and platelet-rich fibrin (L-PROF), and pure platelet-rich fibrin (P-PRF). The primary factor in the success of any PRP treatment is the platelet concentration.

What Are Some Recent Breakthrough Clinical Trials For PRP?

The following PRP clinical trials have been considered to be breakthrough studies in the area of regenerative therapy.

2013 - Systemic Effects of Platelet-Rich Plasma Injection - This review analyzes technological advances in PRP methodologies and their correlation with patient outcomes. The study concluded that there is a lack of standardization classification on PRP.

2021 - A Report on Clinical Studies - This study takes various clinical studies on PRP to compare the level of study across medical fields. It concluded that tendinopathy and knee osteoarthritis are two of the most commonly studied conditions for use with PRP.

Who Are Some Of The Key Opinion Leaders / Researchers / Institutions Conducting PRP Clinical Trials Research?

Chin Research Lab at Stanford Medicine - The Chin Group is focused on using positron emission tomography (PET) imaging to develop novel therapeutics. Their primary interest lies in imaging mysterious diseases such as Alzheimer’s disease, Parkinson’s disease, and other cancers. In 2018, the lab conducted clinical trials on PRP and published their findings on ClinicalTrials.gov.

University of Exeter Medical School was commissioned by the National Institute for Health and Care Research to conduct research on PRP and collect evidence. The medical school is collaborating with other medical institutions, including University of York and UCL Institute of Education.