PRP for Solar Elastosis
Trial Summary
What is the purpose of this trial?
The goal of this study is to assess the safety, tolerability and effectiveness of platelet rich plasma in the treatment of photoaged skin. This study will be divided into two parts. The first part will assess the safety and tolerability of platelet rich plasma injections as compared to sterile saline injections in subjects' arm with six months follow-up. The second part will assess the effect of platelet rich plasma on the appearance of facial skin in a split face study with platelet rich plasma injections on one side of the face and sterile saline on the other. Outcomes will be recorded for twelve months.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are on anticoagulant (blood-thinning) or antiplatelet therapy, or if you require steroids or immunosuppressive agents.
What data supports the effectiveness of the treatment Platelet Rich Plasma (PRP) for Solar Elastosis?
Is PRP generally safe for humans?
How is the PRP treatment for solar elastosis different from other treatments?
PRP (Platelet Rich Plasma) is unique because it uses a concentration of your own blood platelets to release growth factors that help rejuvenate and repair skin, unlike other treatments that may use synthetic ingredients or chemicals. This natural approach reduces the risk of immune reactions and focuses on stimulating the body's own healing processes.123910
Research Team
Murad Alam, MD
Principal Investigator
Northwestern University
Eligibility Criteria
This trial is for men and women aged 35-60 who want to improve facial wrinkles. They must be in good health, understand the study, and consent to participate. Excluded are those with skin cancer history, active skin diseases or infections, immune system issues, blood disorders, recent cosmetic treatments or surgeries on the face, certain allergies like lidocaine allergy, genetic disorders affecting collagen or fibroblasts.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment Part 1
Safety and tolerability of platelet rich plasma injections compared to sterile saline injections in subjects' arm
Treatment Part 2
Effect of platelet rich plasma on facial skin in a split face study with injections on one side of the face
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Platelet Rich Plasma
Platelet Rich Plasma is already approved in United States, European Union for the following indications:
- Facet-mediated lumbar low back pain
- Degenerative joint disease
- Chronic pain
- Orthopedic conditions
- Musculoskeletal disorders
- Pain management
Find a Clinic Near You
Who Is Running the Clinical Trial?
Northwestern University
Lead Sponsor