Testosterone Clinical Trials

Browse 43 Testosterone Medical Studies Across 50 Cities

2 Phase 3 Trial ยท 88 Testosterone Clinics

Reviewed by Michael Gill, B. Sc.
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Top Cities for Testosterone Clinical Trials
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Boston
7Active Trials
Brigham and Women's HospitalTop Active Site
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Seattle
6Active Trials
Fred Hutch/University of Washington Cancer ConsortiumTop Active Site
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Most Recent Testosterone Clinical Trials

What Are Testosterone Clinical Trials?

Testosterone is one of the fundamental male sex hormones responsible for muscle mass, fertility, red blood cell production, and fat distribution. If the testosterone levels drop too low, it can lead to many different medical conditions and problems like infertility and hypogonadism.

Since the problem of low testosterone is becoming widespread, it is important to conduct testosterone clinical trials since it has a huge impact on male fertility. Testosterone levels worldwide are dropping among males, which is why testosterone clinical trials are vital in learning more about what causes it, how to cure it, and how to improve the quality of life for many.

Why Is Testosterone Being Studied in Clinical Trials?

Deficiency of testosterone ranges from 10-40% globally. One study has revealed that testosterone levels in men have been on a substantial decline for decades, averaging around 1% a year.

Low testosterone can result in symptoms such as below:

  • Fatigue
  • Irritability
  • Reduced sex drive
  • Low lean muscle mass
  • Depression
  • Erectile dysfunction

It can be caused by many different factors like congenital conditions, diabetes, obesity, and damage or loss to the testicles.

How Does Testosterone Treatment Work?

People experiencing low testosterone can get Testosterone Replacement Therapy. It comes in the form of gels, patches, pellets, and injections. It is known to improve the symptoms of LT, evening increasing muscle strength and size as well as decreasing fat mass.

What Are Some of the Breakthrough Clinical Trials Involving Testosterone?

2023: Adverse cardiovascular events and mortality in men during testosterone treatment: an individual patient and aggregate data meta-analysis โ€“ The study found that men can get short-to-medium testosterone hormone therapy with no greater risk for cardiovascular diseases such as stroke and heart attacks.

2020: A new oral testosterone undecanoate therapy comes of age for the treatment of hypogonadal men โ€“ New testosterone undecanoate oral formula was effective and safe for hypogonadal treatment. The research studied the short and long-term effects of the drug on hypogonadal men. There were no findings of liver toxicity.

2019: The Testosterone Trials of Older Men โ€“ This ongoing trial is testing whether testosterone therapy can benefit older men with unequivocally low levels of the hormone. The sample is men who have experienced measured abnormalities in any one of five key areas: vitality, sexual or physical function, anemia, and cognition.

Who Are the Key Opinion Leaders On Testosterone Clinical Trial Research?

American Urology Association offers a database of knowledge on testosterone and is continuously working on improving symptoms of low testosterone.

Endocrine Center has ongoing studies on low testosterone and how to effectively treat it among men. They also provide information about low testosterone, creating awareness and gathering funds for further research.

The National Cancer Institute is working on research underlining the benefits of testosterone therapy for prostate cancer.

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 25th, 2021

Last Reviewed: August 13th, 2023

References1 DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol. 1979 Sep;237(3):E214-23. https://pubmed.ncbi.nlm.nih.gov/3828712 Fairhall NJ, Dyer SM, Mak JC, Diong J, Kwok WS, Sherrington C. Interventions for improving mobility after hip fracture surgery in adults. Cochrane Database Syst Rev. 2022 Sep 7;9:CD001704. doi: 10.1002/14651858.CD001704.pub5. Review. https://pubmed.ncbi.nlm.nih.gov/360701343 Fairhall NJ, Dyer SM, Mak JC, Diong J, Kwok WS, Sherrington C. Interventions for improving mobility after hip fracture surgery in adults. Cochrane Database Syst Rev. 2022 Sep 7;9(9):CD001704. doi: 10.1002/14651858.CD001704.pub5. https://pubmed.ncbi.nlm.nih.gov/360701344 DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol. 1979 Sep;237(3):E214-23. doi: 10.1152/ajpendo.1979.237.3.E214. https://pubmed.ncbi.nlm.nih.gov/3828715 Chou R, Turner JA, Devine EB, Hansen RN, Sullivan SD, Blazina I, Dana T, Bougatsos C, Deyo RA. The effectiveness and risks of long-term opioid therapy for chronic pain: a systematic review for a National Institutes of Health Pathways to Prevention Workshop. Ann Intern Med. 2015 Feb 17;162(4):276-86. doi: 10.7326/M14-2559. https://pubmed.ncbi.nlm.nih.gov/255812576 Chou R, Turner JA, Devine EB, Hansen RN, Sullivan SD, Blazina I, Dana T, Bougatsos C, Deyo RA. The effectiveness and risks of long-term opioid therapy for chronic pain: a systematic review for a National Institutes of Health Pathways to Prevention Workshop. Ann Intern Med. 2015 Feb 17;162(4):276-86. doi: 10.7326/M14-2559. Review. https://pubmed.ncbi.nlm.nih.gov/255812577 Snyder PJ, Peachey H, Berlin JA, Hannoush P, Haddad G, Dlewati A, Santanna J, Loh L, Lenrow DA, Holmes JH, Kapoor SC, Atkinson LE, Strom BL. Effects of testosterone replacement in hypogonadal men. J Clin Endocrinol Metab. 2000 Aug;85(8):2670-7. doi: 10.1210/jcem.85.8.6731. https://pubmed.ncbi.nlm.nih.gov/109468648 Snyder PJ, Peachey H, Berlin JA, Hannoush P, Haddad G, Dlewati A, Santanna J, Loh L, Lenrow DA, Holmes JH, Kapoor SC, Atkinson LE, Strom BL. Effects of testosterone replacement in hypogonadal men. J Clin Endocrinol Metab. 2000 Aug;85(8):2670-7. https://pubmed.ncbi.nlm.nih.gov/109468649 Katznelson L, Finkelstein JS, Schoenfeld DA, Rosenthal DI, Anderson EJ, Klibanski A. Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadism. J Clin Endocrinol Metab. 1996 Dec;81(12):4358-65. https://pubmed.ncbi.nlm.nih.gov/895404210 Katznelson L, Finkelstein JS, Schoenfeld DA, Rosenthal DI, Anderson EJ, Klibanski A. Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadism. J Clin Endocrinol Metab. 1996 Dec;81(12):4358-65. doi: 10.1210/jcem.81.12.8954042. https://pubmed.ncbi.nlm.nih.gov/8954042