Testosterone for Opioid Use Disorder
Study Summary
This trial is testing whether testosterone replacement can help improve pain perception, pain tolerance, sexual function, fatigue, and quality of life in men with chronic back pain being treated with opioids who have low testosterone due to their opioid use.
- Opioid Use Disorder
- Pain
- Testicular Hypogonadism
Eligibility Criteria
Inclusion Criteria
You will be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
Find a site
Who is running the clinical trial?
Media Library
Frequently Asked Questions
Are there any available openings for individuals to partake in this experiment?
"Clinicaltrials.gov records indicate that this clinical trial is currently recruiting patients, with the initial posting occurring on January 10th 2022 and a recent update being made on September 16th 2022."
What prior experiments have been done on Testosterone cypionate's effects?
"Currently, there are 29 ongoing clinical trials for Testosterone cypionate and 5 of these trials have been moved to Phase 3. While some of the studies may be located in Houston, Texas, a total of 124 medical sites offer this research opportunity globally."
What potential risks are associated with Testosterone cypionate usage?
"Testosterone cypionate's safety has been partially established, thus receiving a rating of 2 on the scale. However, efficacy remains unconfirmed given this is only a Phase 2 study."
What are the expected outcomes of this medical experiment?
"This 6-month clinical trial has a primary focus of assessing changes in scores for the Pain Interference Subscale of the Brief Pain Inventory (BPI) questionnaire. Furthermore, secondary outcomes include Quantitative sensory testing to measure deep pressure pain response with cuff pressure algometry, quantifying responses to pressure stimulation through digital pressure algometer readings, and gauging reactions to mechanical pain by repetitive stimuli ("windup") tests with punctate probes."
How many participants is this research endeavor recruiting?
"Affirmative. Per the data available on clinicaltrials.gov, this investigation is actively soliciting participants since its inception in January 10th 2022 and most recent refreshment on September 16th of the same year. A total of 150 individuals are required to be recruited from a single research site."
To what medical conditions is testosterone cypionate typically applied?
"Testosterone cypionate is widely prescribed to treat hypogonadotropic hypogonadism, however it can also be taken as a therapy for post-menopausal women and those that have undergone orchidectomy or orchitis."