Pain Reprocessing Therapy for Chronic Knee Pain
(REJOICE Trial)
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It might be best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the treatment Pain Reprocessing Therapy for chronic knee pain?
Pain Reprocessing Therapy (PRT) has shown effectiveness in treating chronic back pain, with two-thirds of patients reporting significant pain relief. This suggests that PRT, which focuses on changing how patients perceive and react to pain, could potentially be beneficial for chronic knee pain as well.12345
Is Pain Reprocessing Therapy safe for treating chronic knee pain?
There is no specific safety data available for Pain Reprocessing Therapy in the provided research articles. However, one study mentions that home-based exercise therapy for knee pain is considered safe and effective, which suggests that non-invasive treatments like Pain Reprocessing Therapy may also be safe.678910
How is Pain Reprocessing Therapy different from other treatments for chronic knee pain?
Pain Reprocessing Therapy (PRT) is unique because it focuses on changing how patients perceive and react to pain, rather than just addressing physical symptoms. It involves reappraising pain to reduce fear, understanding the connection between pain, emotions, and stress, and building supportive relationships with therapists and peers, which can lead to significant pain relief.111121314
What is the purpose of this trial?
The goal of this clinical trial is to learn whether Pain Reprocessing Therapy (PRT) can help adults with knee pain after knee replacement surgery. The study is comparing PRT to usual care (the regular treatment people get after surgery) to see which works better for relieving pain.The main questions the study aims to answer are:1. Does PRT help lower pain in people who have chronic knee pain after knee surgery?2. How do the effects of PRT compare with usual care in terms of pain relief and other factors such as anxiety, depression, and sleep?3. How does PRT impact the brain?Participants will:1. Be randomly assigned to receive either PRT or usual care.2. Complete questionnaires about their pain and health.3. If in the PRT group, have eight weekly therapy sessions over video calls with a therapist.4. If interested, may also take part in an optional EEG test to measure brain activity related to pain.
Eligibility Criteria
This trial is for adults with chronic knee pain after knee replacement surgery. Participants will be randomly assigned to receive either Pain Reprocessing Therapy (PRT) or usual post-surgery care and must be willing to complete questionnaires and possibly undergo an EEG test.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either Pain Reprocessing Therapy (PRT) or usual care for knee pain management
Follow-up
Participants are monitored for pain intensity, opioid use, and psychological outcomes
Treatment Details
Interventions
- Pain Reprocessing Therapy
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Colorado, Denver
Lead Sponsor
Weill Medical College of Cornell University
Collaborator
Hospital for Special Surgery, New York
Collaborator