← Back to Search

Behavioral Intervention

Diet Weight Loss for Obesity

N/A

Recruiting

Research Sponsored by University of Colorado, Denver

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 weeks

Awards & highlights

Study Summary

This trial aims to understand how weight loss affects the signaling of fat tissue in muscles of obese individuals. They want to know how certain molecules released by this fat tissue can cause insulin resistance and inflammation in muscles

Who is the study for?

This trial is for generally healthy men and women aged 18-70 with obesity (BMI between 30-40) who exercise less than one hour per week. It includes both pre or postmenopausal individuals. People who don't meet these criteria cannot participate.Check my eligibility

What is being tested?

The study investigates how a diet-induced weight loss over a period of 12 weeks affects the molecular signaling in muscle fat tissue, which may influence muscle strength and insulin sensitivity in obese individuals.See study design

What are the potential side effects?

While not explicitly listed, potential side effects might include typical risks associated with dietary changes such as nutrient deficiencies, fatigue, mood swings, or gastrointestinal discomfort.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Body Weight

IMAT Content

Insulin Sensitivity

+2 more

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Diet Weight LossExperimental Treatment1 Intervention

Low calorie meal replacement shakes

Group II: Delayed InterventionActive Control1 Intervention

Normal feeding

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Diet Weight Loss

1997

N/A

Unknown

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NIH

2,364 Previous Clinical Trials

4,315,332 Total Patients Enrolled

447 Trials studying Obesity

588,916 Patients Enrolled for Obesity

National Institutes of Health (NIH)NIH

2,705 Previous Clinical Trials

7,507,216 Total Patients Enrolled

103 Trials studying Obesity

25,786 Patients Enrolled for Obesity

University of Colorado, DenverLead Sponsor

1,742 Previous Clinical Trials

2,152,689 Total Patients Enrolled

100 Trials studying Obesity

213,639 Patients Enrolled for Obesity

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are prospective patients still eligible to participate in this ongoing medical study?

"As per information from clinicaltrials.gov, this research investigation is currently in the process of recruiting suitable candidates. The commencement date of this study was 1st January 2024 and its most recent update occurred on 22nd April 2024."

Answered by AI

Are participants who are younger than 65 years of age eligible for enrollment in this research trial?

"Patients must be between 18 and 70 years old to participate in this investigation. There are a total of 211 studies targeting individuals under the age of 18, as well as 894 trials focusing on participants aged over 65."

Answered by AI

What is the current size of the patient cohort being observed in this clinical investigation?

"Indeed, data available on clinicaltrials.gov indicates that this research investigation is actively seeking suitable participants. The trial was publicly listed on 1st January 2024 and underwent its latest update on 22nd April 2024. Recruitment aims to enroll a total of 70 patients at one designated site."

Answered by AI

Which individuals are eligible to participate in this research investigation?

"The trial seeks to enroll 70 obese individuals aged 18-70 who meet specific requirements: a body mass index (BMI) falling within the range of 30-40, engaging in less than one hour of physical activity weekly, possibly experiencing menopause or having already gone through it, and being generally healthy adult males and females between the ages of 18-70."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling

2024. "Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06129110.