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Rhenium Liposome Treatment for Brain Cancer
Study Summary
This trial is testing a new cancer treatment to see if it is safe and effective. It uses a modified Fibonacci dose escalation, which means it starts with a small dose and increases the dose each time until the maximum tolerated dose is reached. The starting absorbed dose is 1mCi in a volume of 0.660mL.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- My tumor is 20 cm3 or smaller.I have a genetic condition that increases my risk of bleeding.I've been on a stable dose of my seizure medication for at least two weeks without seizures.My liver function tests are within the required range.My condition affects the lower part of my brain.My tumor is close to a brain ventricle, posing a risk for drug leakage.I am 18 years old or older.My kidney function is within normal limits.I still have significant side effects from cancer treatment drugs.My brain tumor is a high-grade glioma that has come back.My brain tumor has grown despite treatment.I have been on a stable or decreasing dose of steroids for brain swelling for at least two weeks without worsening symptoms.My brain tumor is a high-grade glioma within the treatment area.I can care for myself and am up more than 50% of my waking hours.I understand the study's risks and have signed the consent form.I have previously received treatments like Bevacizumab or chemotherapy for cancer.
- Group 1: 186Rhenium Liposome Treatment
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are investigators still looking for new participants for this research study?
"The trial, which is currently looking for participants, was originally posted on 6/3/2015. The last update was on 7/12/2022 according to clinicaltrials.gov"
How large is the sample size for this experiment?
"The answer is affirmative, this study is detailed on clinicaltrials.gov and actively recruiting patients. This particular trial was posted on 6/3/2015, with the latest update being on 7/12/2022. The research team are looking to enroll 55 people from 3 different locations."
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