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Autism Clinical Trials
Autism Spectrum Disorder studies recruiting patients for novel treatments. Filter by phase, distance, and inclusion criteria to find your perfect autism clinical trial.
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Cognitive behavioral therapy for Insomnia
Philadelphia, PA
Any Age
All Sexes
Waitlist Available
Philadelphia, PA
Any Age
All Sexes
Autism Spectrum Disorder (ASD) represents one of the most perplexing neurobiological disorders with a prevalence of 1 in 54 children. The lifelong challenging and disruptive behaviors often associated with ASD requires caregivers to change their behavior and modify their environments to pr…
Tasimelteon Oral Capsule, Tasimelteon Liquid Suspension
San Leandro, CA
Any Age
All Sexes
Phase 3
Recruiting
San Leandro, CA
Any Age
All Sexes
This is a multicenter, open-label study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon in treating sleep disturbances in pediatric and adult participants with ASD.
ATTAIN NAV Technology-Enhanced Family Navigation Model
San Diego, CA
< 18
All Sexes
Recruiting
San Diego, CA
< 18
All Sexes
This project, Refining and Implementing Technology-Enhanced Family Navigation to Promote Early Access and Engagement with Mental Health Services for Youth with Autism (ATTAIN NAV) is focused on adapting and implementing family navigation in primary care settings to help accelerate and faci…
Educational Intervention: online didactic lecture and educational simulation activity
New York, NY
Any Age
All Sexes
Waitlist Available
New York, NY
Any Age
All Sexes
The objective is to evaluate the efficacy of an online learning module combined with high fidelity simulation-based training in improving medical assistants' and registered nurses' self-confidence and competence scores in taking vital signs in a child with Autism Spectrum Disorder in clini…
Cognitive Behavioral Therapy-Email (iCBT-E)
Houston, TX
< 18
All Sexes
Recruiting
Houston, TX
< 18
All Sexes
This study compares the effectiveness of two levels of therapist support for an internet-based, parent-led cognitive behavioral therapy for youth with anxiety and ASD.
Family Check-Up
Hamilton, Canada
< 18
All Sexes
Waitlist Available
Hamilton, Canada
< 18
All Sexes
Many children and youth with autism spectrum disorder have high levels of emotional and behavioural problems. Parents play a powerful role in supporting their children's well-being. Research also shows that certain factors (e.g., parent mental health, access to services) can affect autisti…
Exploring predictors of response to a peer-mediated communication intervention for minimally verbal preschoolers with ASD
Kansas City, KS
< 18
All Sexes
Recruiting
Kansas City, KS
< 18
All Sexes
This study will examine what child variables (i.e., social attention and peer interest) predict communication gains in response to a peer-mediated intervention for 40 minimally-verbal preschool children with ASD and 80 peers. The Stay-Play-Talk with iPad intervention will be implemented fo…
Bilateral TMS
Cincinnati, OH
< 65
All Sexes
Recruiting
Cincinnati, OH
< 65
All Sexes
In this research study the investigators aim to learn more about the therapeutic effects of a newer form of non-invasive transcranial magnetic stimulation (TMS), called theta burst simulation (TBS), on refractory depression in Autism Spectrum Conditions.
Micronutrient
San Francisco, CA
< 65
All Sexes
Phase 2
Waitlist Available
San Francisco, CA
< 65
All Sexes
An open-label examination of changes in metabolites with use of micronutrients in children with autism spectrum disorder (ASD). Investigators will also measure behavioral measures monthly at school with teachers and parents report.
Thinking in Speech
Pittsburgh, PA
< 18
All Sexes
Pittsburgh, PA
< 18
All Sexes
This study examines a cognitive therapy for autistic children, Thinking in Speech. Thinking in Speech helps children with autism independently cope with everyday events that cause stress, by developing their ability to use "inner speech".
repetitive transcranial magnetic stimulation (rTMS)
Toronto, Canada
< 65
All Sexes
Phase 2
Waitlist Available
Toronto, Canada
< 65
All Sexes
This study will evaluate the feasibility of repetitive Transcranial Magnetic Stimulation (rTMS) in Autism Spectrum Disorder (ASD) with self-regulation impairment. Baseline and follow-up participant visits will include behavioral assessments of self-regulation and magnetic resonance imaging…
Electronic platform
Philadelphia, PA
18+
All Sexes
Recruiting
Philadelphia, PA
18+
All Sexes
In partnership with a digital health software company, the University research team created two versions of a mobile application to help behavioral health technicians (BHT's) who work with students with autism collect data. The first version comprises a basic electronic platform for data c…
Experimental Condition (360° Video)
Toronto, Canada
< 18
All Sexes
Toronto, Canada
< 18
All Sexes
The objective of this study is to evaluate the effectiveness of virtual reality (360° video) compared to a social story for reducing pre-visit dental anxiety for children with autism spectrum disorder (ASD) improve the dental visit experience for children, their families, and clinicians. T…
Overheard Speech
Boston, MA
< 18
All Sexes
Waitlist Available
Boston, MA
< 18
All Sexes
The goal of this research is to explore abilities to learn word meanings from overheard conversations in children with ASD (and, as a control, typically developing children). Specific Aim 3 (Experiment 3): Determine whether children with ASD can learn verbs and pronouns by overhearing. Mo…
Overheard Speech
New York, NY
< 18
All Sexes
Recruiting
New York, NY
< 18
All Sexes
The goal of this research is to explore abilities to learn word meanings from overheard conversations in children with ASD (and, as a control, typically developing children). Specific Aim 2 (Experiment 2): Determine whether children with ASD can learn from addressed and overheard teaching…
Growth Hormone
New York, NY
< 18
All Sexes
Phase 2
Recruiting
New York, NY
< 18
All Sexes
This clinical trial will use growth hormone as a novel treatment for Phelan-McDermid syndrome (PMS) and idiopathic autism. A double-blind, placebo-controlled crossover trial design will be used in 30 children with idiopathic autism and 15 children with PMS to evaluate the the effects of gr…
PEERS social skills intervention
Loma Linda, CA
< 65
All Sexes
Recruiting
Loma Linda, CA
< 65
All Sexes
Difficulties in reciprocal social interaction are hallmark features of several neuropsychiatric disorders, most notably autism spectrum disorder (ASD) and schizophrenia spectrum disorder (SSD). While recent studies have demonstrated substantial overlap in genetic etiology between ASD and S…
INP105
Cincinnati, OH
< 18
All Sexes
Phase 2
Waitlist Available
Cincinnati, OH
< 18
All Sexes
This is a Phase 2a, proof-of concept, 2-way, 2-period crossover, double-blind study to evaluate the safety and efficacy of INP105 as an acute treatment versus placebo in adolescents with autism spectrum disorder (ASD) experiencing agitation. Approximately 32 ASD patients who are currently …
Play-based assessment (RITA-T)
Ann Arbor, MI
Any Age
All Sexes
Recruiting
Ann Arbor, MI
Any Age
All Sexes
The goal of the study is to assess a new autism evaluation model that would include the addition of a Level-2 autism screener, the Rapid Interactive Screening Test for Autism in Toddlers (RITA-T), to the developmental screening already done by the child's pediatrician. The study hypothese…
Executive function group therapy
Washington, United States
< 65
All Sexes
Recruiting
Washington, United States
< 65
All Sexes
This project explores the association between learning and cognitive flexibility by testing whether a cognitive behavioral intervention designed to improve flexibility in ASD changes learning and associated neural activation using model-based functional magnetic resonance imaging (m-fMRI).…
Facing Your Fears: ASD/ID
Aurora, CO
< 65
All Sexes
Recruiting
Aurora, CO
< 65
All Sexes
Adolescents with ASD and intellectual disability (ID) are a complex and underserved population. Approximately 50% of individuals with ASD/ID experience significant anxiety. Yet, there are very limited mental health care interventions available for this population. Addressing anxiety and bu…
Reciprocal Imitation Training
Boston, MA
< 18
All Sexes
Recruiting
Boston, MA
< 18
All Sexes
This study is evaluating whether a parent-mediated intervention can improve outcomes for children with autism.
Sham tDCS
New Brunswick, NJ
< 18
All Sexes
Waitlist Available
New Brunswick, NJ
< 18
All Sexes
This study is evaluating whether a combination of tDCS and ABA can improve learning in children with ASD.
Sibling-mediated intervention
Round Rock, TX
< 18
All Sexes
Recruiting
Grade I
Round Rock, TX
< 18
All Sexes
This study is evaluating whether a set of activities can improve social skills in children with autism.
RUBIES
Seattle, WA
Any Age
All Sexes
Recruiting
Seattle, WA
Any Age
All Sexes
This study is evaluating whether a new intervention can reduce disruptive behavior in children with autism.
Aquatic Occupational Therapy
Columbus, OH
< 18
All Sexes
Recruiting
Columbus, OH
< 18
All Sexes
This study is evaluating whether an aquatic therapy program can improve safety skills in children with autism.
L1-79
Chicago, IL
< 65
All Sexes
Phase 2
Recruiting
Chicago, IL
< 65
All Sexes
This study will investigate the efficacy, safety and tolerability of L1-79 in participants aged 12-21 years who have been diagnosed with ASD with a score of >/= 70 on the Wechsler Abbreviated Scale of Intelligence (WASI-II), and a score of >/= 4 on the Clinical Global Impression of Severit…
Gabapentin
Worcester, MA
< 18
All Sexes
Phase 4
Recruiting
Locally Advanced
Worcester, MA
< 18
All Sexes
This study is evaluating whether a surgery which reduces blood flow in a stomach artery leads to significant weightloss.
Tele-PCIT
Charleston, SC
< 18
All Sexes
Charleston, SC
< 18
All Sexes
The purpose of this research study is to evaluate a time-limited version of Parent Child Interaction Therapy (PCIT) delivered via telehealth for young children with autism spectrum disorder (ASD) and disruptive behavior problems. Families will be randomly assigned to receive 10 sessions of…
Tele-assessment + in-person assessment
Sacramento, CA
Any Age
All Sexes
Recruiting
Sacramento, CA
Any Age
All Sexes
This study is evaluating whether a telemedicine tool can be used to assess for autism spectrum disorder (ASD) symptoms in toddlers.
Behavioral Interventions for Anxiety in Children with Autism (BIACA)
Culver City, CA
< 18
All Sexes
Recruiting
Culver City, CA
< 18
All Sexes
This study is evaluating whether cognitive behavioral therapy (CBT) is more effective than usual clinical care for children with autism and emotional dysregulation.
BeatIt-ASD
Piscataway, NJ
18+
All Sexes
Recruiting
Piscataway, NJ
18+
All Sexes
This study is evaluating whether a behavioral activation intervention can be adapted for people with intellectual disabilities.
Unstuck & On Target: High School
Rockville, MD
< 65
All Sexes
Rockville, MD
< 65
All Sexes
This study is evaluating whether a school-based cognitive behavioral executive function (EF) intervention, Unstuck and On Target High School (UOT:HS), can improve EF skills for transition-age youth with autism spectrum disorder (ASD).
The Listening Program® with bone conduction headphones
Richardson, TX
< 18
All Sexes
Recruiting
Locally Advanced
Richardson, TX
< 18
All Sexes
There are limited approaches to specifically address auditory sensory over- and under-responsivity (SOR) in children with Autism Spectrum Disorder (ASD). Exposure therapy (or systematic desensitization) may be a treatment option; researchers are investigating this approach. Many children r…
Sensory adaptive environment
Dayton, OH
< 18
All Sexes
Dayton, OH
< 18
All Sexes
This study is evaluating whether ASD patients have higher anxiety scores in an adaptive sensory environment.
Smartphone-App Parent Training in Pivotal Response Treatment
Santa Barbara, CA
< 18
All Sexes
Recruiting
Santa Barbara, CA
< 18
All Sexes
This study is evaluating whether a smartphone app-based parent training program is feasible, acceptable, and effective for parents of children with autism.
Cognitive Support Technology (CST)
Kent, OH
Any Age
All Sexes
Recruiting
Kent, OH
Any Age
All Sexes
This study is evaluating whether a technology-driven, long-term, and resource-rich individualized support program that merges assistive technology for cognition and vocational rehabilitation practices can improve the employment outcomes of students with Autism Spectrum Disorder.
Self-Determined Learning Model of Instruction (SDLMI)
Lawrence, KS
Any Age
All Sexes
Recruiting
Newly Diagnosed
Lawrence, KS
Any Age
All Sexes
This study is evaluating whether a set of activities can improve social skills in people with autism.
Remaking Recess (RR)
Rochester, NY
< 18
All Sexes
Recruiting
Newly Diagnosed
Rochester, NY
< 18
All Sexes
This study is evaluating whether a set of activities can improve social skills in children with autism.
Mind the Gap
Davis, CA
Any Age
All Sexes
Recruiting
Newly Diagnosed
Davis, CA
Any Age
All Sexes
This study is evaluating whether a set of activities can improve sleep habits in people with dementia.
Mindfulness-Based Music and Songwriting
Nashville, TN
18+
All Sexes
Recruiting
Nashville, TN
18+
All Sexes
This study is evaluating whether a mindfulness program can improve stress and well-being in parents of children with intellectual or developmental disabilities.
Emotional Support Plan - Self Guided (ESP-S)
Piscataway, NJ
Any Age
All Sexes
Recruiting
Piscataway, NJ
Any Age
All Sexes
This study is evaluating whether a program that provides emotional support can help autistic students.
Mobile Game System for Potential Treatment of Developmental Delays
Stanford, CA
< 18
All Sexes
Waitlist Available
Stanford, CA
< 18
All Sexes
This study is evaluating whether a mobile game system can help children with autism.
Center-Based Pivotal Response Treatment (PRT) Intervention (PRT-C)
Stanford, CA
< 18
All Sexes
Waitlist Available
Stanford, CA
< 18
All Sexes
This study is evaluating whether a specific type of therapy is more effective than other types of therapy for children with autism.
AB-2004
Woburn, MA
< 18
All Sexes
Phase 2
Recruiting
Woburn, MA
< 18
All Sexes
This study is evaluating whether a drug called AB-2004 might help treat irritability in people with autism.
Help is in Your Hands
Sacramento, CA
Any Age
All Sexes
Recruiting
Sacramento, CA
Any Age
All Sexes
This study is evaluating whether a set of online materials can help parents of children with autism.
Autism ALERT
Portland, OR
< 18
All Sexes
Recruiting
Portland, OR
< 18
All Sexes
This study is evaluating whether a new program can help children with autism receive the care they need.
ANRC Essentials Plus
Tempe, AZ
< 18
All Sexes
Recruiting
Tempe, AZ
< 18
All Sexes
This study is evaluating whether a vitamin/mineral supplement may help improve symptoms of autism.
KF-STRIDE
East Hanover, NJ
< 65
All Sexes
Recruiting
East Hanover, NJ
< 65
All Sexes
This study is evaluating whether a program which helps individuals identify and express their strengths may help improve their mental health.
Sulforaphane
Piscataway, NJ
< 65
Male
Waitlist Available
Piscataway, NJ
< 65
Male
This study is evaluating whether digital biomarkers can be used to better understand the effects of sulforaphane treatment.
Continuous Theta Burst Stimulation
Bethesda, MD
< 65
All Sexes
Recruiting
Bethesda, MD
< 65
All Sexes
Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental syndrome. Researchers think brain development may be controlled by gamma-aminobutyric acid (GABA). They want to learn how abnormalities in the GABA system may contribute to ASD. Objective: To see if repetitive tr…
Training to Understand and Navigate Emotions and Interactions (TUNE In)
Philadelphia, PA
18+
All Sexes
Recruiting
Philadelphia, PA
18+
All Sexes
The purpose of this study is to test a novel, three-part cognitive behavioral treatment strategy to improve social functioning in adults with autism spectrum disorder. The treatment, named TUNE In (Training to Understand and Navigate Emotions and Interactions), includes components to addr…
Hippotherapy
Gretna, NE
< 18
All Sexes
Recruiting
Gretna, NE
< 18
All Sexes
This study is evaluating whether hippotherapy may be beneficial for children with autism spectrum disorders.
VR-JIT/KF-STRIDE
East Hanover, NJ
< 65
All Sexes
Recruiting
East Hanover, NJ
< 65
All Sexes
This study is evaluating whether a virtual reality program may help improve social skills for adolescents with autism spectrum disorder.
GWP42003-P
Ottawa, Canada
< 18
All Sexes
Phase 2
Recruiting
Ottawa, Canada
< 18
All Sexes
This study is evaluating whether a drug called GWP42003-P can help reduce symptoms in children with autism.
Autism Parent Navigators
Columbia, SC
Any Age
All Sexes
Recruiting
Newly Diagnosed
Columbia, SC
Any Age
All Sexes
This study is evaluating whether a new type of support for parents of children with autism may help improve family functioning.
GuessWhat Mobile App
Stanford, CA
< 18
All Sexes
Recruiting
Stanford, CA
< 18
All Sexes
This study is evaluating whether a mobile game platform can help improve social skills for children with autism spectrum disorder.
Toy Talk
White Plains, NY
< 18
All Sexes
Recruiting
White Plains, NY
< 18
All Sexes
This study is evaluating whether a new intervention can help improve early language development in children.
Cognitive behavior therapy (CBT), specifically using the Facing Your Fears (FYF) curriculum
Toronto, Canada
< 18
All Sexes
Recruiting
Toronto, Canada
< 18
All Sexes
This study is evaluating whether a virtual delivery of a group CBT program is helpful in improving anxiety symptoms for children and youth with ASD.
Cognilum TM: Light Treatment Condition
Brooklyn, NY
< 18
All Sexes
Recruiting
Brooklyn, NY
< 18
All Sexes
This study is evaluating whether a type of light therapy may help reduce symptoms of autism.
Flore
Tempe, AZ
Any Age
All Sexes
Phase < 1
Recruiting
Tempe, AZ
Any Age
All Sexes
This study is evaluating whether a customized probiotic may help improve autism symptoms and gastrointestinal symptoms.
Behavioral Therapy for Irritability in Autism
New Haven, CT
< 65
All Sexes
Recruiting
New Haven, CT
< 65
All Sexes
This study is evaluating whether a new therapy may help adolescents with autism spectrum disorder.
Consultee-centered administrative consultation
East Lansing, MI
18+
All Sexes
Recruiting
East Lansing, MI
18+
All Sexes
This study is evaluating whether a consultation model can help improve the implementation of parent-mediated interventions for autism spectrum disorder.
Fecal Microbiota Transplant
Ventura, CA
Any Age
All Sexes
Phase 1
Waitlist Available
Ventura, CA
Any Age
All Sexes
This study is evaluating whether fecal transplantation may help improve social deficits and language delays in individuals with autism spectrum disorder.
Hybrid
Portland, ME
< 18
All Sexes
Recruiting
Portland, ME
< 18
All Sexes
This study is evaluating whether horseback riding may help improve symptoms of autism spectrum disorder.
CICADAS and then PEERS
Minneapolis, MN
< 65
All Sexes
Recruiting
Minneapolis, MN
< 65
All Sexes
This study is evaluating whether a mobile application may help improve social-emotional learning for individuals with autism spectrum disorder.
Remote sleep hygiene and related education (SHARE) for insomnia in children with autism
Columbia, MO
< 18
All Sexes
Recruiting
Columbia, MO
< 18
All Sexes
This study is evaluating whether behavioral therapy for sleep problems in children with autism spectrum disorder may improve sleep and daytime behavior.
Oral cannabidiol 100mg/mL
Aurora, CO
< 18
All Sexes
Phase 2
Recruiting
Aurora, CO
< 18
All Sexes
This study is evaluating whether cannabidiol may have positive impacts for individuals with epilepsy.
Epidiolex
La Jolla, CA
< 18
Male
Phase 2 & 3
La Jolla, CA
< 18
Male
This study is evaluating whether cannabidiol may have positive impacts for individuals with autism.
ASD Screening Parent ENgagement Intervention Program (ASPEN)
San Marcos, TX
< 18
All Sexes
Recruiting
San Marcos, TX
< 18
All Sexes
This study is evaluating whether a program which provides psychoeducation and coaching to parents of children with developmental delays will improve child and parent outcomes.
hCT-MSC
Durham, NC
18 - 65
All Sexes
Phase 1
Recruiting
Durham, NC
18 - 65
All Sexes
This study is evaluating whether a single intravenous dose of Human Umbilical Cord Tissue Derived Mesenchymal Stromal Cells (hCT-MSC) in adults with
Occupational Therapy in an Equine Environment
Fort Collins, CO
< 18
All Sexes
Fort Collins, CO
< 18
All Sexes
This study is evaluating whether occupational therapy for youth with autism is more effective in a clinic environment than in an equine environment.
Emotional Support Plan
Piscataway, NJ
18+
All Sexes
Piscataway, NJ
18+
All Sexes
This study is evaluating whether a brief telehealth intervention can help autistic adults cope with negative emotions during the COVID-19 pandemic.
tDCS
Dallas, TX
< 18
All Sexes
Recruiting
Locally Advanced
Dallas, TX
< 18
All Sexes
This study is evaluating whether a non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) may help improve symptoms of autism spectrum disorder.
DINO Strategies for Anxiety and fear of Uncertainty Reduction (DINOSAUR)
Baltimore, MD
< 18
All Sexes
Recruiting
Baltimore, MD
< 18
All Sexes
This study is evaluating whether a treatment program for anxiety in preschool children with autism spectrum disorder is feasible, acceptable, and has preliminary efficacy.
SENSE Theatre
Nashville, TN
18 - 65
All Sexes
Recruiting
Nashville, TN
18 - 65
All Sexes
This study is evaluating whether a theatre-based intervention may help improve social cognition and behavior in adults with autism spectrum disorder.
Usability assessment of Cognoa ASD Therapeutic Device
Palo Alto, CA
< 18
All Sexes
Recruiting
Palo Alto, CA
< 18
All Sexes
This study is evaluating whether a device may help improve socialization for individuals with autism spectrum disorder.
LCPUFA Oil Supplement
Columbus, OH
< 18
All Sexes
Phase 2
Columbus, OH
< 18
All Sexes
This study is evaluating whether a specific diet may help reduce symptoms of autism spectrum disorder.
RO7017773
London, Canada
< 65
All Sexes
Phase 2
Recruiting
London, Canada
< 65
All Sexes
This study is evaluating whether a drug may help improve symptoms of autism spectrum disorder.
Unstuck and on Target (UOT)
San Diego, CA
< 18
All Sexes
Waitlist Available
San Diego, CA
< 18
All Sexes
This study is evaluating whether a specific intervention may help improve executive functioning for individuals with autism spectrum disorder.
hCT-MSC infusion
Durham, NC
< 18
All Sexes
Phase 1
Durham, NC
< 18
All Sexes
This study is evaluating whether a single infusion of human umbilical cord tissue-derived mesenchymal stromal cells (hCT-MSC) may help improve autism symptoms in
N-Acetylcysteine
Stanford, CA
< 18
All Sexes
Phase 2
Recruiting
Stage I
Stanford, CA
< 18
All Sexes
This study is evaluating whether a nutritional supplement may help reduce symptoms of autism spectrum disorder.
My Autism Passport (MAP) Application
Toronto, Canada
< 18
All Sexes
Waitlist Available
Toronto, Canada
< 18
All Sexes
This study is evaluating whether a mobile application can help families of children with autism access services.
Brexpiprazole
Princeton, NJ
< 18
All Sexes
Phase 3
Princeton, NJ
< 18
All Sexes
This study is evaluating whether brexpiprazole is safe and well tolerated in children and adolescents with irritability associated with autism spectrum disorder.
JASPER
Los Angeles, CA
< 18
All Sexes
Recruiting
Los Angeles, CA
< 18
All Sexes
In this project, the investigator will test the effect of augmenting an evidence based joint attention intervention (JASPER) with a motor-sound system intervention (PROMPT) compared to JASPER only on speech and language outcomes. The investigator will model change over a year to determine …
vancomycin, Miralax, intestinal microbiota
Tempe, AZ
< 18
All Sexes
Phase 2
Recruiting
Tempe, AZ
< 18
All Sexes
This study is evaluating whether a combination of antibiotics and fecal matter may help treat children with autism.
Brexpiprazole
Princeton, NJ
< 18
All Sexes
Phase 3
Waitlist Available
Princeton, NJ
< 18
All Sexes
This study is evaluating whether brexpiprazole may have positive impacts for individuals with autism spectrum disorder.
ASSIST
Nashville, TN
Any Age
All Sexes
Nashville, TN
Any Age