Cognitive Enhancement Therapy for Autism
(PerspectivesII Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial will test two therapies for adults with autism. One therapy aims to improve thinking and planning through mental exercises. The other provides support to help manage emotions and social skills. The study focuses on adults because there are few treatments available for them.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It might be best to discuss this with the trial coordinators.
Is Cognitive Enhancement Therapy safe for adults with autism?
How is Cognitive Enhancement Therapy for Autism different from other treatments?
Cognitive Enhancement Therapy (CET) is unique because it combines supportive therapy with social skills and cognitive training to improve thinking and social abilities, originally developed for schizophrenia. It focuses on enhancing cognitive functions and social interactions through group exercises and interactive software, which may offer a novel approach for autism compared to traditional therapies.678910
What data supports the effectiveness of the treatment Cognitive Enhancement Therapy for Autism?
Cognitive Enhancement Therapy (CET) has shown benefits in improving thinking skills and social functioning in people with schizophrenia, suggesting it might help with similar challenges in autism. Studies have found that CET can enhance cognitive and social abilities, which are often areas of difficulty for individuals with autism.678911
Who Is on the Research Team?
Nancy J Minshew, Ph.D.
Principal Investigator
University of Pittsburgh
Shaun M Eack, Ph.D.
Principal Investigator
University of Pittsburgh
Are You a Good Fit for This Trial?
Adults aged 16-45 with autism, Asperger's syndrome, or pervasive developmental disorder not otherwise specified (NOS), who have an IQ over 80 and significant social/cognitive challenges. Participants must speak English fluently, be able to attend sessions in Pittsburgh, PA, and have a supportive person for information sharing.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either Cognitive Enhancement Therapy (CET) or Enriched Supportive Therapy (EST) for 18 months
Follow-up
Participants are monitored for the lasting impact of the study interventions
What Are the Treatments Tested in This Trial?
Interventions
- Cognitive Enhancement Therapy
- Enriched Supportive Therapy
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Pittsburgh
Lead Sponsor
National Institute of Mental Health (NIMH)
Collaborator