Speech Tasks for Speech Perception
Trial Summary
What is the purpose of this trial?
The basic mechanisms underlying comprehension of spoken language are still largely unknown. Over the past decade, the study team has gained new insights to how the human brain extracts the most fundamental linguistic elements (consonants and vowels) from a complex and highly variable acoustic signal. However, the next set of questions await pertaining to the sequencing of those auditory elements and how they are integrated with other features, such as, the amplitude envelope of speech. Further investigation of the cortical representation of speech sounds can likely shed light on these fundamental questions. Previous research has implicated the superior temporal cortex in the processing of speech sounds, but little is known about how these sounds are linked together into the perceptual experience of words and continuous speech. The overall goal is to determine how the brain extracts linguistic elements from a complex acoustic speech signal towards better understanding and remediating human language disorders.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the study team or your doctor.
What data supports the effectiveness of the treatment Speech Tasks for speech perception?
Research suggests that formal training in speech perception tasks can help individuals adapt to changes in hearing, improving their ability to understand speech. This training has shown benefits in enhancing skills and self-perceived competence, which may support the effectiveness of Speech Tasks in improving speech perception.12345
Is the Speech Tasks treatment safe for humans?
How is the Speech Tasks treatment different from other treatments for speech perception?
The Speech Tasks treatment is unique because it focuses on using specific speech tasks to improve speech perception, which involves understanding how we categorize and process speech sounds. This approach is different from other treatments that might focus on auditory training or hearing aids, as it directly targets the cognitive processes involved in speech perception.811121314
Research Team
Edward F Chang, MD
Principal Investigator
University of California, San Francisco
Eligibility Criteria
This trial is for individuals at UCSF with epilepsy or brain tumors who are undergoing surgical electrode implantation. They must have electrodes in at least two key brain areas and be able to perform study tasks. Those unable to consent, with significant cerebral lesions, or cognitive deficits that prevent task completion cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Intraoperative Procedure
Participants undergo ECoG recording during speech tasks while undergoing surgery for seizure localization or awake intraoperative brain mapping
Inpatient Hospitalization
Participants may have ECoG signals recorded during inpatient hospitalization
Follow-up
Participants are monitored for safety and effectiveness after the procedure
Treatment Details
Interventions
- Speech Tasks
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, San Francisco
Lead Sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
Collaborator
University of California, Berkeley
Collaborator