Study Summary
This trial is testing whether leucine will help increase muscle mass in people with cirrhosis, by looking at the response to leucine in cirrhotic patients compared to a control group. They will measure this by looking at the rate of protein synthesis in muscle, and how this changes in response to leucine.
Eligible Conditions
- Liver Cirrhosis
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 0 Secondary · Reporting Duration: Baseline to 90 days
Baseline to 90 days
Compare Fractional Synthesis Rate
Trial Safety
Safety Progress
Trial Design
2 Treatment Groups
Balanced amino acid supplement
1 of 2
Leucine enriched essential amino acid
1 of 2
Active Control
32 Total Participants · 2 Treatment Groups
Primary Treatment: Balanced amino acid supplement · No Placebo Group · N/A
Balanced amino acid supplement
DietarySupplement
ActiveComparator Group · 1 Intervention: Balanced amino acid supplement (BAA) · Intervention Types: DietarySupplementLeucine enriched essential amino acid
DietarySupplement
ActiveComparator Group · 1 Intervention: Leucine enriched essential amino acid (EEA/LEU) · Intervention Types: DietarySupplementTrial Logistics
Trial Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline to 90 days
Who is running the clinical trial?
The Cleveland ClinicLead Sponsor
949 Previous Clinical Trials
1,409,720 Total Patients Enrolled
6 Trials studying Liver Cirrhosis
223 Patients Enrolled for Liver Cirrhosis
Eligibility Criteria
Age 18 - 70 · All Participants · 10 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top
Conditions
Cancer Related
Treatments