Ovarian tissue transplant for Primary Ovarian Insufficiency

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Primary Ovarian Insufficiency+1 MoreOvarian tissue transplant - Procedure
Eligibility
18 - 45
Female
What conditions do you have?
Select

Study Summary

This trial is studying whether it is safe to give patients their own frozen ovarian tissue after chemotherapy and/or radiation treatments for cancer.

Eligible Conditions
  • Female Infertility
  • Primary Ovarian Insufficiency

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

3 Primary · 3 Secondary · Reporting Duration: Through study completion, up to 15 years

Month 24
Change in reproductive hormone levels after ovarian tissue transplant
Fertility quality of life (FertiQoL) survey results
Surgical complications of ovarian tissue transplantation
Year 15
Achievement of successful pregnancy, measured by live birth
Cancer recurrence as determined by patient's oncologist
Return of regular monthly menstrual cycles

Trial Safety

Safety Progress

1 of 3

Trial Design

1 Treatment Group

Ovarian tissue transplant
1 of 1

Experimental Treatment

5 Total Participants · 1 Treatment Group

Primary Treatment: Ovarian tissue transplant · No Placebo Group · N/A

Ovarian tissue transplant
Procedure
Experimental Group · 1 Intervention: Ovarian tissue transplant · Intervention Types: Procedure

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: through study completion, up to 15 years

Who is running the clinical trial?

University of PittsburghLead Sponsor
1,617 Previous Clinical Trials
16,295,437 Total Patients Enrolled
1 Trials studying Primary Ovarian Insufficiency
13 Patients Enrolled for Primary Ovarian Insufficiency
Kyle Orwig, PhDPrincipal Investigator - University of Pittsburgh/University of Pittsburgh Medical Center
University of Pittsburgh
4 Previous Clinical Trials
1,256 Total Patients Enrolled

Eligibility Criteria

Age 18 - 45 · Female Participants · 4 Total Inclusion Criteria

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Who else is applying?

What state do they live in?
Massachusetts100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%