128 Participants Needed

ACT Lung Health Intervention for Smoking

MC
Overseen ByMary Cooley, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Dana-Farber Cancer Institute
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a program designed to help Chinese and Korean American smokers quit smoking, aiming to reduce their risk of lung cancer. Participants will either receive the new counseling program (ACT Lung Health Intervention) or standard care while researchers monitor them through surveys and tests over six months. This trial suits current smokers with a long history of smoking who have not recently undergone a specific lung screening test. Participants should also live in the U.S. and have access to a device for video calls.

As an unphased trial, this study offers a unique opportunity to contribute to innovative research that could benefit the community.

Do I need to stop my current medications to join the trial?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that this counseling and educational program is safe for improving lung health?

Research has shown that programs designed to help people stop smoking, such as the ACT Lung Health Intervention, are generally manageable for participants. In studies of similar programs, participants have not reported any major side effects. These programs emphasize counseling and education to aid in quitting smoking, without the need for new medications or medical procedures.

Regular check-ins and support sessions are often included, which participants in similar studies have found helpful and safe. Safety concerns remain low because the program employs behavior change techniques instead of new drugs, reducing the risks typically associated with medication trials.

Overall, evidence suggests these programs are safe, with participants primarily experiencing positive outcomes in quitting smoking.12345

Why are researchers excited about this trial?

Researchers are excited about the ACT Lung Health Intervention because it takes a fresh approach to helping people quit smoking. Unlike traditional methods like nicotine replacement therapies and prescription medications, this intervention incorporates Acceptance and Commitment Therapy (ACT) principles. ACT focuses on helping individuals accept their cravings and commit to quitting without fighting their urges head-on. This psychological approach, combined with regular support through weekly Zoom sessions and personalized strategies, offers a unique and potentially more effective way to address the emotional and mental challenges of quitting smoking.

What evidence suggests that the ACT Lung Health Intervention is effective for smoking cessation?

Studies have shown that Acceptance and Commitment Therapy (ACT) can help people quit smoking. Research indicates that a smartphone app based on ACT proved more effective in helping users quit than a typical smoking cessation app. Another study found that people using the ACT method were more likely to attempt quitting compared to those using other methods. Typically, without structured help, only about 3%-5% of people successfully quit smoking. In this trial, participants in Group A will receive the ACT Lung Health Intervention, which could be a promising way to support quitting smoking and improve lung health. Meanwhile, participants in Group B will receive standard care.678910

Who Is on the Research Team?

MC

Mary Cooley, PhD

Principal Investigator

Dana-Farber Cancer Institute

Are You a Good Fit for This Trial?

The ACT Lung Health Intervention trial is for Chinese and Korean American smokers aged 50-80 with a significant smoking history, who currently smoke and have health insurance, a primary healthcare provider, and can video-call. Excluded are those under 50 or over 80, unable to consent, pregnant women, prisoners, recent serious mental illness hospitalization or previous lung cancer.

Inclusion Criteria

I am between 50-80 years old and have a history of smoking equivalent to 20 pack-years.
Self-identify as either Chinese or Korean
Currently have active health insurance coverage and a primary healthcare provider
See 5 more

Exclusion Criteria

Had LDCT screening done within the last 2 years
I am between 50 and 80 years old, can consent, am not pregnant, and not imprisoned.
I have not been hospitalized for a serious mental illness in the last 6 months.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks
1 visit (in-person)

Baseline Assessment

Participants complete baseline visit and initial questionnaires

1 week
1 visit (in-person)

Intervention

Participants receive counseling and educational program for smoking cessation

6 months
Weekly Zoom sessions, questionnaires at 1, 3, and 6 months, saliva tests at 3 and 6 months

Follow-up

Participants are monitored for smoking abstinence and lung cancer screening completion

6 months
Questionnaires and saliva tests

What Are the Treatments Tested in This Trial?

Interventions

  • ACT Lung Health Intervention
Trial Overview This phase two study tests a counseling and educational program aimed at helping high-risk lung cancer candidates among Chinese and Korean American smokers quit smoking to improve their lung health.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Group A: ACT Lung Health InterventionExperimental Treatment1 Intervention
Group II: Group B: Standard CareActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Dana-Farber Cancer Institute

Lead Sponsor

Trials
1,128
Recruited
382,000+

National Cancer Institute (NCI)

Collaborator

Trials
14,080
Recruited
41,180,000+

University of Massachusetts, Boston

Collaborator

Trials
42
Recruited
17,800+

Citations

A Review of Smoking Cessation Interventions - PubMed CentralMoreover, attempting to quit smoking without any structured approach yielded a mere 3%-5% success rate within the same timeframe [7]. This study ...
Efficacy of Smartphone Applications for Smoking CessationThis trial provides evidence that, compared with a USCPG-based smartphone application, an ACT-based smartphone application was more efficacious for quitting ...
ACT on Vaping: Pilot Randomized Controlled Trial of a Novel ...A higher proportion of participants in the ACT on Vaping arm reported a 24-hour quit attempt (87.5% vs. 75.9%), exceeding the efficacy benchmark ...
Comparative effectiveness of mobile health smoking ...The primary outcome is 7-day point prevalence of smoking abstinence at 6 months. Secondary outcomes are: 12-month smoking abstinence, and patient satisfaction ...
Study Results | Promoting Smoking Cessation in Lung Cancer ...A group or subgroup of participants in a clinical trial that receives a specific intervention/treatment, or no intervention, according to the trial's protocol.
Strategies to deliver smoking cessation interventions during ...This systematic review addressed the effectiveness of smoking cessation intervention strategies delivered as a component of lung health screening programmes.
Smoking Cessation Interventions in the Lung Cancer ...This randomized clinical trial evaluates the effectiveness of smoking cessation interventions of varying intensities in the lung cancer ...
Smoking Cessation Pharmacotherapy-Nurse Practitioner ...The investigators, proposed sample (n= 424 total patients) has 90% power to detect a clinically meaningful 15% improvement in smoking cessation rates at 6 ...
Annals of the American Thoracic SocietyWe hypothesize that smoking abstinence rates will be higher with the addition of each intervention when compared with arm 1. We will enroll ...
Efficacy and safety of electronic cigarettes as a smoking ...This systematic review of randomized controlled trials (RCTs) evaluated the efficacy and safety of electronic cigarettes (e-cigarettes, ...
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