At-home tDCS for Autism
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine if transcranial direct current stimulation (tDCS) can benefit children with Autism Spectrum Disorder (ASD). The focus is on enhancing social communication and self-regulation, common challenges for those with ASD. Participants will receive either the active tDCS treatment at home or a placebo version (a treatment that appears the same but lacks active effects) for three weeks. This trial suits children with ASD who struggle with social skills or self-control and do not have a history of seizures or metal implants. As a Phase 2 trial, the research measures the treatment's effectiveness in an initial, smaller group of participants.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that at-home tDCS is safe for children and youth with Autism Spectrum Disorder?
Research shows that using transcranial direct current stimulation (tDCS) at home is generally safe and well-tolerated. Previous studies found that tDCS is a non-invasive method safely used in adults. Researchers are exploring its potential to help with social communication and self-control, especially in young people with Autism Spectrum Disorder (ASD).
The studies indicate that this method usually does not cause serious side effects. Some people might feel minor discomfort, like tingling or itching on the scalp, but these effects are typically mild and temporary. Since this treatment is being tested in a Phase 2 trial, it has already passed initial safety tests in humans. This phase aims to learn more about how well people handle it and how it might affect the intended results.12345Why do researchers think this study treatment might be promising for Autism?
Researchers are excited about at-home tDCS for autism because it offers a unique, non-invasive way to potentially enhance brain function. Unlike traditional therapies like behavioral interventions or medication, tDCS involves applying a mild electrical current to the scalp to modulate brain activity, which can be done comfortably at home. This method could provide a more accessible and flexible treatment option, especially for individuals who have difficulty attending in-person therapy sessions. Additionally, the sham arm of the study allows researchers to effectively measure the real impact of tDCS by comparing it to a placebo-like experience, ensuring that any observed benefits are due to the treatment itself.
What evidence suggests that At-home tDCS is effective for improving social communication and self-regulation in youth with Autism?
Research has shown that using a device at home called transcranial direct current stimulation (tDCS) can help children with Autism Spectrum Disorder (ASD) improve their social skills and better manage their emotions. In this trial, participants will receive either active tDCS or sham tDCS, which serves as a placebo. Studies found that children using active tDCS showed noticeable improvements compared to those not using the device. This treatment is safe and simple to use at home, offering a convenient option for families. Additionally, significant reductions in autism symptoms occurred after both short-term and long-term use. These findings suggest that tDCS could effectively help children with ASD enhance their social and cognitive skills.34567
Are You a Good Fit for This Trial?
This trial is for children with Autism Spectrum Disorder (ASD) who have difficulties with self-regulation or social communication. They must be able to participate in at-home brain stimulation treatments.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either active tDCS or sham control stimulation for 3 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- At-home tDCS
- Sham at-home tDCS
Find a Clinic Near You
Who Is Running the Clinical Trial?
Holland Bloorview Kids Rehabilitation Hospital
Lead Sponsor