Speech Tasks for Aura

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of California, San Francisco, San Francisco, CA
Aura+4 More
Speech Tasks - Behavioral
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

This study is evaluating whether the brain can be stimulated to learn new languages.

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Eligible Conditions

  • Aura
  • Neoplasms, Brain
  • Speech
  • Bilingualism

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

This trial is evaluating whether Speech Tasks will improve 1 primary outcome in patients with Aura. Measurement will happen over the course of Between 10-30 minutes.

Between 10-30 minutes
Number of Participants with Electrocorticography (ECoG) Signals for Neural Activity Identified During Intraoperative Procedure or Inpatient Hospitalization

Trial Safety

Safety Progress

1 of 3

Trial Design

1 Treatment Group

Electrocorticography (ECoG) recording during Speech Tasks
1 of 1
Experimental Treatment

This trial requires 52 total participants across 1 different treatment group

This trial involves a single treatment. Speech Tasks is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Electrocorticography (ECoG) recording during Speech Tasks
Behavioral
Participants listened to 20-minute Speech Tasks while ECoG signals for neural activity was recorded during their intraoperative procedure or inpatient hospitalization at the University of California, San Francisco (UCSF).

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: between 10-30 minutes
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly between 10-30 minutes for reporting.

Closest Location

University of California, San Francisco - San Francisco, CA

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 2 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Participants with epilepsy or brain tumors at UCSF undergoing surgical electrode implantation for seizure localization or for speech and language mapping
Participants with electrodes implanted in at least two regions of interest who are willing and able to cooperate with study tasks.

Patient Q&A Section

What are the latest developments in speech tasks for therapeutic use?

"SSTT may be used to assess certain aspects of speech processing. The use of SSTT is recommended for evaluating patients with disorders of language comprehension, especially when the performance of the patient on other speech tests is suboptimal." - Anonymous Online Contributor

Unverified Answer

Who should consider clinical trials for brain cancer?

"The majority of respondents were satisfied with the current status of clinical trials in brain cancer. However, the majority of respondents would like more information about clinical trials of anti-angiogenesis agents currently being conducted in India. Many respondents wanted to know when clinical trials would be available before considering them. Results from a recent paper shows that there is high interest and support among patients and clinicians alike for conducting clinical trials of anti-angiogenesis agents." - Anonymous Online Contributor

Unverified Answer

Does speech tasks improve quality of life for those with brain cancer?

"There were improvements in speech performance and quality of life post intervention. This suggests that speech therapy may facilitate better quality of life for individuals with brain tumours." - Anonymous Online Contributor

Unverified Answer

What does speech tasks usually treat?

"Recent findings will help us understand which treatment options might benefit patients with HFA who need a lot of speech therapy input for their communication needs." - Anonymous Online Contributor

Unverified Answer

What is the survival rate for brain cancer?

"Survival rates differ depending upon the type of tumor. Invasive tumor types tend to have better prognoses than non-invasive tumor types, except in patients with glioblastoma multiforme. Surgical resection is advisable for most tumors, especially when they are small, well-differentiated, and pave tractable areas of the brain. Patients who received radiation therapy after surgery had significantly longer survival rates than those who did not receive radiation. The prognostic factors were determined by univariate and multivariate analyses. A multivariate analysis was conducted using the Cox regression model." - Anonymous Online Contributor

Unverified Answer

Has speech tasks proven to be more effective than a placebo?

"Recent findings suggest that using semantic verbal fluency tests may decrease the risk of developing aphasia. A timely assessment of language abilities is important during the postoperative period of surgery after a tumor resection. Further research is needed to confirm these findings." - Anonymous Online Contributor

Unverified Answer

What are common treatments for brain cancer?

"A number of different treatments exist for patients with [brain tumor](https://www.withpower.com/clinical-trials/brain-tumor)s including surgery, radiation therapy, chemotherapy, targeted therapy, immunotherapy, and hormonal therapy. The choice depends on many factors including the location, type, and stage of the tumor. The most commonly used treatment options include surgery, radiotherapy, chemotherapy, and targeted therapy with monoclonal antibodies.\n" - Anonymous Online Contributor

Unverified Answer

What is speech tasks?

"In a recent study, the subjects were asked to state their ability to understand commands after several days of training. This task has been used previously in studies where patients with cochlear implants have shown good comprehension of commands. The result of this study confirms the findings of previous studies, showing that cochlear implant users can comprehend commands when they listen to these commands repeatedly. Moreover, our data suggest that even those who have never spoken before can learn to respond appropriately to commands after only a few hours of instruction." - Anonymous Online Contributor

Unverified Answer

What is brain cancer?

"It seems so strange that brain cancer is so rare, but that the brain is so important! We need to know why brain cancer is so rare, and how it can be prevented? We also need to remember that brain cancer is often diagnosed too late. So many brain cancer patients don't have the chance they deserve. This article describes some facts about brain cancer and how to prevent it. It also tells us why it is so important to try to find out why brain cancer is so rare. It might help us learn something about what causes brain cancer. And hopefully it will make our children safer." - Anonymous Online Contributor

Unverified Answer

How many people get brain cancer a year in the United States?

"The number of new cases of primary [brain cancer](https://www.withpower.com/clinical-trials/brain-cancer)s in the US has increased over time, probably because incidence rates of other types of brain cancer are increasing faster than incidence rates of primary brain cancers. No trend toward increasing incidence rates of secondary brain cancers exists for most common primary brain cancers." - Anonymous Online Contributor

Unverified Answer

Does brain cancer run in families?

"Recent findings brings together epidemiological, biological, and statistical information on familial breast cancer demonstrating that the commonality between families with familial breast cancer is consistent with a hereditary predisposition." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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