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Speech Tasks for Understanding Brain Processing of Language

N/A

Waitlist Available

Led By Edward F Chang, MD

Research Sponsored by University of California, San Francisco

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up between 10-30 minutes

Awards & highlights

Study Summary

This trial is studying how the human brain extracts linguistic elements from speech. They will be recording neural activity from people speaking different languages to try and understand how the brain processes speech.

Who is the study for?

This trial is for individuals at UCSF with epilepsy or brain tumors who are undergoing surgery involving electrode implantation. They must be able to perform study tasks and have electrodes in at least two key brain areas. Those unable to consent, with significant cerebral lesions, or cognitive deficits that prevent task completion cannot participate.Check my eligibility

What is being tested?

The study aims to understand how the brain processes speech across different languages by recording neural activity during surgery. It uses high-density electrodes and signal processing on patients speaking Mandarin, Spanish, and English to explore phonetic encoding in the temporal cortex.See study design

What are the potential side effects?

Since this research involves non-invasive observation of neural activity during a surgical procedure already planned for other medical reasons, there are no additional side effects directly associated with the trial's interventions.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ between 10-30 minutes

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~between 10-30 minutes

This trial's timeline: 3 weeks for screening, Varies for treatment, and between 10-30 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Number of Participants with Electrocorticography (ECoG) Signals for Neural Activity Identified During Intraoperative Procedure or Inpatient Hospitalization

Trial Design

1Treatment groups

Experimental Treatment

Group I: Electrocorticography (ECoG) recording during Speech TasksExperimental Treatment1 Intervention

Participants listened to 20-minute Speech Tasks while ECoG signals for neural activity was recorded during their intraoperative procedure or inpatient hospitalization at the University of California, San Francisco (UCSF).

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of California, San FranciscoLead Sponsor

2,505 Previous Clinical Trials

15,237,503 Total Patients Enrolled

2 Trials studying Speech

90 Patients Enrolled for Speech

University of California, BerkeleyOTHER

181 Previous Clinical Trials

721,104 Total Patients Enrolled

1 Trials studying Speech

60 Patients Enrolled for Speech

The University of Hong KongOTHER

1,118 Previous Clinical Trials

1,303,521 Total Patients Enrolled

Media Library

Speech Tasks Clinical Trial Eligibility Overview. Trial Name: NCT05014841 — N/A

Speech Research Study Groups: Electrocorticography (ECoG) recording during Speech Tasks

Speech Clinical Trial 2023: Speech Tasks Highlights & Side Effects. Trial Name: NCT05014841 — N/A

Speech Tasks 2023 Treatment Timeline for Medical Study. Trial Name: NCT05014841 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who has the appropriate qualifications to join this experiment?

"This clinical trial seeks 52 individuals with aura, aged 18 to 70. In order for a patient's application to be successful, they must meet the following criteria: epilepsy or brain tumor patients who have had surgical electrode implantation at UCSF for either seizure localisation or speech and language mapping; participants who are willing and able to cooperate in study tasks with electrodes implanted into multiple areas of interest."

Answered by AI

Is the minimum age requirement for this trial less than 25 years old?

"Those aged 18 to 70 may qualify for this trial, with 184 trials available for minors and 505 clinical studies targeting those over 65."

Answered by AI

Are there any vacancies left in the clinical trial for participants?

"The clinical trial's information on the website, clinicaltrials.gov, shows that this study is no longer querenting participants; its first posting was April 19th 2019 and it was last updated January 29th 2022. Nevertheless, 648 other studies are presently recruiting patients at this time."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

The Neural Coding of Speech Across Human Languages

2019. "The Neural Coding of Speech Across Human Languages". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05014841.

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