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Inhibitory Control Training for Healthy Aging
N/A
Waitlist Available
Led By Fang Jiang, Ph.D
Research Sponsored by University of Nevada, Reno
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 30 days after training
Awards & highlights
Study Summary
This trial will research how age-related declines in multisensory & postural control relate to changes in GABA-mediated inhibition & network segregation. It will assess & train inhibitory functions with the potential to develop new rehabilitation protocols for older adults.
Who is the study for?
This trial is for older adults aged between 65 and 80, as well as a younger group aged between 20 and 35. Participants must not have serious vision or uncorrected hearing problems, early dementia, cognitive impairments, epilepsy, stroke, Parkinson's disease, Alzheimer's disease, ADHD or history of significant head injury.Check my eligibility
What is being tested?
The study investigates if inhibitory control training can improve multisensory temporal processing and postural control in older adults by affecting GABA-mediated inhibition in the brain. It compares this method to knowledge-based training through a multimodal approach.See study design
What are the potential side effects?
Since the interventions involve non-pharmacological cognitive training methods rather than medication or invasive procedures, no direct side effects are expected from participating in this clinical trial.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 30 days after training
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~30 days after training
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Brain GABA level change
Brain GABA level change maintenance
Multisensory temporal processing performance change
+5 moreTrial Design
2Treatment groups
Experimental Treatment
Placebo Group
Group I: Inhibitory control trainingExperimental Treatment1 Intervention
In the inhibitory control training condition, participants will be trained with tasks that involve both response withholding and rule switching. For example, participants will sort polygons based on features (e.g., shape or color) and will be asked to either provide or withhold sorting responses when presented with different cues. Rule-switching is introduced when participants must inhibit the "rule" used in the previous trial set and change the focus of their attention to a new sorting and/or inhibitory rule. Task difficulty will progressively increase over the course of training based on participants' abilities.
Group II: knowledge-based trainingPlacebo Group1 Intervention
The knowledge-based training condition serves as the control, in which participants will be presented with questions from different categories such as vocabulary, science, or geography and asked to select the correct answer from 4 alternatives within a certain time limit. Task difficulty will progressively increase over the course of training based on participants' abilities.
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Who is running the clinical trial?
University of Nevada, RenoLead Sponsor
30 Previous Clinical Trials
18,714 Total Patients Enrolled
Fang Jiang, Ph.DPrincipal InvestigatorUniversity of Nevada, Reno
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Eligibility Criteria:
This trial includes the following eligibility criteria:- I have a history of epilepsy, stroke, Parkinson's, Alzheimer's, or ADHD.I am either between 20-35 or 65-80 years old.I have been diagnosed with early dementia or mild cognitive impairment.You have a history of serious head injury, brain surgery, or mental health disorders.
Research Study Groups:
This trial has the following groups:- Group 1: Inhibitory control training
- Group 2: knowledge-based training
Awards:
This trial has 0 awards, including:Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are individuals aged 75 and above eligible to participate in the trial?
"This clinical trial has designated an age range of 20 to 80 years old as being eligible for enrollment."
Answered by AI
How can I become a participant of this research endeavor?
"Access to this trial is restricted to individuals with healthy aging and an age range of 20 - 80 years old. The recruitment quota for the study stands at 50 patients."
Answered by AI
Are there any available places for participants in this research?
"According to the information found on clinicaltrials.gov, this medical experiment is not presently recruiting patients. It was published on July 1st 2023 and its last update happened February 21st 2023. Nevertheless, there are 49 other trials actively searching for volunteers at this time."
Answered by AI
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