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Behavioural Intervention

Exercise and Cognitive Training for Mild Cognitive Impairment

N/A

Recruiting

Research Sponsored by University of Maryland, Baltimore

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up at baseline and within one week after the corresponding training program.

Awards & highlights

Study Summary

This trial explores if combining brain & exercise training can improve brain health & cognition, in those with mild impairment & healthy seniors. Goal: find ways to prevent or treat dementia by 2025. #alzheimers

Who is the study for?

This trial is for adults aged 50-80 with mild cognitive impairment (MCI), who are sedentary, fluent in English, and can use an iPad or computer. They must be able to live independently despite cognitive deficits. Those with a BMI over 40, severe medical conditions, or inability to undergo MRI due to metal implants or claustrophobia cannot participate.Check my eligibility

What is being tested?

The study tests if brain function improves after a combined 12-week program of brain training and aerobic exercise in people with MCI. It explores potential treatments for dementia by assessing changes in the brain and cognition through this dual intervention approach.See study design

What are the potential side effects?

Potential side effects from participating may include typical exercise-related risks such as muscle soreness or strain. Cognitive training is generally low-risk but could potentially cause some frustration or mental fatigue.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ at baseline and within one week after the corresponding training program.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~at baseline and within one week after the corresponding training program.

This trial's timeline: 3 weeks for screening, Varies for treatment, and at baseline and within one week after the corresponding training program. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Changes in Blood Bioenergetic Markers

Changes in Brain Activation on functional MRI

Changes in Brain blood flow from Arterial spin labeling magnetic resonance imaging (ASL-MRI) in milliliters/100 g/minutes

+5 more

Secondary outcome measures

VO2peak

Trial Design

3Treatment groups

Experimental Treatment

Group I: Combined Cognitive and Aerobic ExerciseExperimental Treatment1 Intervention

Combined progressive aerobic exercise 3x/week for 12 weeks and adaptive cognitive training on Cogmed 5x/week for a total of 25 sessions in 5-8 weeks simultaneously.

Group II: Cognitive TrainingExperimental Treatment1 Intervention

Adaptive cognitive training on Cogmed 5x/week for a total of 25 sessions in 5-8 weeks.

Group III: Aerobic ExerciseExperimental Treatment1 Intervention

Progressive aerobic exercise 3x/week for 12 weeks.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Combined

2011

Completed Phase 3

~970

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of Maryland, BaltimoreLead Sponsor

688 Previous Clinical Trials

374,566 Total Patients Enrolled

Media Library

Adaptive cognitive training (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05948930 — N/A

Mild Cognitive Impairment Research Study Groups: Combined Cognitive and Aerobic Exercise, Aerobic Exercise, Cognitive Training

Mild Cognitive Impairment Clinical Trial 2023: Adaptive cognitive training Highlights & Side Effects. Trial Name: NCT05948930 — N/A

Adaptive cognitive training (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05948930 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Am I eligible to take part in this experiment?

"This clinical trial seeks 90 individuals with mild cognitive impairment aged 50-80 to participate. Eligibility criteria necessitates that patients meet the aforementioned age and health qualifications."

Answered by AI

Is there an age limit for participants in this research?

"This medical trial is open to those who are between the ages of 50 and 80 years old."

Answered by AI

Are there vacancies in this experiment for participants?

"The information provided on clinicaltrials.gov states that this particular study is not recruiting patients at the present time, having been initially posted and last updated in August and July of 2023 respectively. That said, 612 other medical trials are actively accepting participants as we speak."

Answered by AI