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Behavioral Intervention

JASPER Intervention for Autism (EBJ Trial)

N/A
Recruiting
Research Sponsored by University of California, Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
The child must be between 18 months and 5 years of age
The sample will be limited to children with confirmed diagnosis and nonverbal mental ages greater than or equal to 12 months
Timeline
Screening 3 weeks
Treatment Varies
Follow Up entry (1st month of the study), t2 (10 weeks after entry), t3 (20 weeks after entry)
Awards & highlights

EBJ Trial Summary

This trial will study whether JASPER, a play-based intervention, is effective in treating children with autism spectrum disorder. The trial will last 3 years, recruiting 90 participants (10 per site per year) from Boston University, UCLA, and Weill Cornell. The participants will be randomized to receive JASPER from either a clinician or their caregiver, and after 10 weeks, will be evaluated to see if they respond to the treatment. Nonresponders will then receive a mix of clinician and caregiver-facilitated JASPER, while responders will continue to receive the same treatment for an additional 10 weeks. The outcome of

Who is the study for?
This trial is for children aged 18 months to 5 years with Autism Spectrum Disorder who are minimally verbal or have emerging phrase speech. They must have a nonverbal mental age of at least 12 months and a confirmed diagnosis of autism.Check my eligibility
What is being tested?
The study tests JASPER, a play-based intervention for autism, delivered by either clinicians or parents. It measures the effectiveness using BOSCC and ELSA-T assessments over a period of 20 weeks, with adjustments based on initial response after the first half.See study design
What are the potential side effects?
Since JASPER is a behavioral intervention involving structured play activities facilitated by clinicians or caregivers, it does not involve medication; therefore, traditional physical side effects are not expected.

EBJ Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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My child is between 18 months and 5 years old.
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My child has a confirmed diagnosis and understands things like a 1-year-old or older.

EBJ Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~entry (1st month of the study), t2 (10 weeks after entry), t3 (20 weeks after entry)
This trial's timeline: 3 weeks for screening, Varies for treatment, and entry (1st month of the study), t2 (10 weeks after entry), t3 (20 weeks after entry) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in frequency of language utterances and number of conversation turns using the Elicitation of Language Samples for Analysis- Toddlers (ELSA-T)
Change in social communication using the Brief Observation of Social Communication Change (BOSCC)
Other outcome measures
ADOS Toddler Module or Module 1 or Module 2 (depends on child's language level)
Change in Joint Engagement on the Caregiver-Child Play Interaction (CCX) over the course of the study.
Demographic and Medical Questionnaire
+4 more

EBJ Trial Design

2Treatment groups
Experimental Treatment
Group I: parent-mediated JASPERExperimental Treatment1 Intervention
This group will consist of the therapist assisting the parent implement JASPER on the child twice a week.
Group II: clinician-mediated JASPERExperimental Treatment1 Intervention
This group will consist of the child and therapist having one-on-one, JASPER sessions, twice a week.

Find a Location

Who is running the clinical trial?

University of California, Los AngelesLead Sponsor
1,532 Previous Clinical Trials
10,265,178 Total Patients Enrolled
Simons FoundationOTHER
7 Previous Clinical Trials
101,166 Total Patients Enrolled

Media Library

JASPER (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT04146428 — N/A
Autism Research Study Groups: parent-mediated JASPER, clinician-mediated JASPER
Autism Clinical Trial 2023: JASPER Highlights & Side Effects. Trial Name: NCT04146428 — N/A
JASPER (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04146428 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many individuals have been selected to take part in this research initiative?

"To fulfill the trial requirements, 90 individuals who meet all of the eligibility criteria must participate. The Semel Institute in Boston and BU White Plains are two medical centers which currently offer this clinical trial."

Answered by AI

Does this research still have vacancies open to the public?

"According to the clinicaltrials.gov documents, enrollment is still open for this trial that was first advertised on 27th April 2021 and last modified on 2nd September 2022."

Answered by AI

Does this research endeavor include elderly individuals as participants?

"This experiment is seeking to enrol participants aged between 18 months and 5 years."

Answered by AI

What criteria must potential participants fulfill in order to join this experiment?

"This trial is seeking 90 participants that are between 18 months and 5 years old, diagnosed with autism spectrum disorder."

Answered by AI

Who else is applying?

What site did they apply to?
Weill Cornell Medical College/New York Presbyterian Hospital
What portion of applicants met pre-screening criteria?
Did not meet criteria
How many prior treatments have patients received?
0
Recent research and studies
clinicaltrials.govStudy
Evaluating BOSCC and ELSA as Outcome Measures in the Context of a JASPER Intervention Trial
Connie Kasari, Ph.D. 2021. "Evaluating BOSCC and ELSA as Outcome Measures in the Context of a JASPER Intervention Trial". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04146428.
All > Autism Los Angeles > Autism
~23 spots leftby Apr 2025
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