Your session is about to expire
← Back to Search
Folinic Acid for Language Impairment in Autism Spectrum Disorder
Study Summary
This trial will test if folinic acid can help improve language skills in children with autism spectrum disorder.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2016 Phase 3 trial • 1072 Patients • NCT01183780Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- You have a low score on a language test.I weigh at least 15 kilograms.My educational or treatment plan will not change for the next 3 months.I have a mental health condition like depression or bipolar disorder.English is spoken at home and at least one parent can read, write, and speak English.You have been clinically diagnosed with Autism Spectrum Disorder and the diagnosis has been confirmed by specific tests.I do not have any health conditions that would make it unsafe for me to take the study drug.My child has stopped taking Bactrim for 2 months.My medications have been the same for the last 6 weeks and won't change during the study.I have serious behavioral issues that need treatment.You have been diagnosed with Autism Spectrum Disorder using specific tests and assessments.You have a high level of severity in both autism spectrum disorder and communication delay.You have a certain level of language skills as measured by a specific test.I have been in a stable speech therapy program for at least a month with no changes expected for the next 12 weeks.My child is on medication for seizures.Your IQ is below 40 or your mental age is less than 18 months.I am between 5 and 17 years old.I have been in a stable speech therapy program for at least a month with no changes expected for the next 12 weeks.You scored less than 80 on a language test called the Clinical Evaluation of Language Fundamentals.I am between 5 and 17 years old.Your current rating for the severity of your ASD and communication delay is 4 or higher according to clinical assessment.My child takes more vitamins or minerals than the daily amount recommended.I am not taking valproic acid, its derivatives, or lamotrigine.I weigh at least 15 kilograms.
- Group 1: Folinic Acid
- Group 2: Placebo Control
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Am I qualified to join this medical experiment?
"Those wishing to partake in this research trial must have autism spectrum disorder and be between 5-17 years old. 134 individuals are required for the entirety of the study."
Are there still openings to join this clinical experiment?
"Unfortunately, this clinical trial is not currently enrolling patients. According to the data hosted on clinicialtrials.gov, it was posted on August 13th 2020 and last updated September 28th 2022. For those searching for other studies, there are 293 trials recruiting individuals with autism spectrum disorder and 265 seeking volunteers for Folinic Acid research."
How many individuals are being monitored in this medical experiment?
"This drug trial is no longer taking on new patients; it was first posted in August of 2020 and the last update to its profile happened at the end of September 2022. If you are looking for alternative studies, 293 clinical trials related to autism spectrum disorder and 265 involving Folinic Acid have open recruitment periods right now."
What conditions can be treated with Folinic Acid?
"Folinic Acid is the traditional therapeutic approach for managing methotrexate toxicity, though it has also proven effective in treating normochromic anemia, advanced esophageal cancers and folate deficiencies."
Has Folinic Acid obtained clearance from the Food and Drug Administration?
"Despite the lack of evidence for efficacy, Folinic Acid has a safety rating of 2 due to existing data that suggests it is relatively safe."
How many establishments are currently administering this trial?
"This trial is accepting participants from the Phoenix Children's Hospital in Arizona, Southwestern Research and Resource Centre in California, Stanford University Department of Psychiatry and Behavioural Sciences in Massachusetts as well as 6 additional medical sites."
Is the sample population for this study limited to those older than 30 years?
"To meet the eligibility criteria for this study, individuals must be aged between 5 and 17. There are 273 studies that focus on subjects younger than 18 years old and 285 targeting those above 65 years of age."
What other experiments have centered around Folinic Acid?
"Currently, there are 265 trials assessing Folinic Acid's efficacy. Of these studies, 84 are in the last phase of clinical research with many located at Woolloongabba, Queensland. Across 15022 sites worldwide, this acid is being subjected to further medical scrutiny."
Who else is applying?
What state do they live in?
How old are they?
What portion of applicants met pre-screening criteria?
What site did they apply to?
Why did patients apply to this trial?
Share this study with friends
Copy Link
Messenger