PROLONGED FASTING INTERVENTION for Cancer Prevention

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Cancer Prevention+5 MoreProlonged Fasting Intervention - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test whether a prolonged nightly fasting intervention can prevent overweight and obese individuals with blood cancer from developing the disease.

Eligible Conditions
  • Cancer Prevention
  • Monoclonal Gammopathy of Unknown Significance
  • Weight Loss
  • Fasting
  • Multiple Myeloma
  • Waldenstrom Macroglobulinemia

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 4 Secondary · Reporting Duration: Baseline to 4-months

Baseline to 4-months
(M-)protein concentrations/light chains change by mass spectrometry
Bone Marrow
Mass Spectrometry
baseline to 4-months
Changes in body composition
Body Weight Changes

Trial Safety

Trial Design

2 Treatment Groups

EDUCATION CONTROL
1 of 2
PROLONGED FASTING INTERVENTION
1 of 2

Active Control

Experimental Treatment

40 Total Participants · 2 Treatment Groups

Primary Treatment: PROLONGED FASTING INTERVENTION · No Placebo Group · N/A

PROLONGED FASTING INTERVENTION
Behavioral
Experimental Group · 1 Intervention: Prolonged Fasting Intervention · Intervention Types: Behavioral
EDUCATION CONTROL
Behavioral
ActiveComparator Group · 1 Intervention: EDUCATION CONTROL · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline to 4-months

Who is running the clinical trial?

Dana-Farber Cancer InstituteLead Sponsor
1,016 Previous Clinical Trials
393,776 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,071 Previous Clinical Trials
41,128,815 Total Patients Enrolled
3 Trials studying Cancer Prevention
1,233 Patients Enrolled for Cancer Prevention
Catherine Marinac, Ph.DPrincipal InvestigatorDana-Farber Cancer Institute

Eligibility Criteria

Age 18+ · All Participants · 6 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are at least 18 years old.
You are currently fasting for <14 hours per night, as assessed using 24-hour food recalls.
You own a cell phone and are comfortable sending and receiving text messages.
You are able to understand the nature and purpose of the study and are willing to sign a written informed consent document.