260 Participants Needed

Text Message Education for Heart Disease in HIV/AIDS

Recruiting at 1 trial location
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Overseen ByMegan McLaughlin, MD, MPH
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of California, San Francisco
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

The overall objective is to evaluate the efficacy of educational text messages to reduce cardiovascular risk among persons living with HIV (PLWH).

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications.

What data supports the effectiveness of the treatment Digital Educational Messaging for heart disease in HIV/AIDS?

Research shows that text messaging interventions can improve health outcomes in people living with HIV and other chronic diseases. Additionally, educational text messages have been effective in promoting healthy behaviors and self-management in conditions like coronary heart disease.12345

Is text message-based health education safe for humans?

Text message-based health education has been used safely in various programs, such as improving learning for midwives and providing health information to pregnant women and new mothers, without any reported safety concerns.46789

How is the treatment of Digital Educational Messaging for heart disease in HIV/AIDS unique?

Digital Educational Messaging is unique because it uses text messages to provide health education, which is a low-cost, instant, and widely accessible method to support behavior change and improve health literacy, unlike traditional treatments that may rely on in-person visits or medications.3471011

Research Team

MM

Megan McLaughlin, MD, MPH

Principal Investigator

University of California, San Francisco

Eligibility Criteria

This trial is for English-speaking adults over 40 years old who are living with HIV but do not have existing cardiovascular disease. Participants must own a smartphone and be willing to provide informed consent. Pregnant individuals cannot participate.

Inclusion Criteria

I am 40 years old or older.
You have HIV.
English-speaking

Exclusion Criteria

I have heart disease related to artery blockage.
Pregnant
Unwilling/unable to provide informed consent
See 1 more

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive educational text messages about HIV and heart disease risk 3-5 times per week for up to 6 months

6 months
Monthly surveys via digital platform

Follow-up

Participants are monitored for cardiovascular risk factors and health outcomes after the intervention

4 weeks

Treatment Details

Interventions

  • Digital Educational Messaging
Trial OverviewThe TEACH-HIV trial is testing whether educational text messages can help reduce the risk of heart disease in people with HIV. The effectiveness of these digital messages will be evaluated over time.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: Intervention ArmExperimental Treatment1 Intervention
The intervention arm will receive education about HIV and heart disease risk via mobile phone text messages for up to 6 months. They will receive the text messages 3-5 times per week. The messages will include information about HIV and risk of heart disease and information about how to reduce heart disease risk. The intervention arm will also receive brief monthly surveys via a digital research platform.
Group II: Control ArmActive Control1 Intervention
The control arm will not receive the educational text messages. They will receive brief monthly surveys via a digital research platform.

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of California, San Francisco

Lead Sponsor

Trials
2,636
Recruited
19,080,000+

National Heart, Lung, and Blood Institute (NHLBI)

Collaborator

Trials
3,987
Recruited
47,860,000+

Findings from Research

A systematic review and meta-analysis of six randomized controlled trials involving 1,158 patients found that text message interventions had no significant effect on self-management outcomes for coronary heart disease, including self-efficacy and various health metrics like LDL and BMI.
The study concluded that using text messages as a method to improve treatment adherence and control risk factors in coronary heart disease patients does not provide any positive benefits compared to usual care.
The Impact of Text Message On Self-Management for Coronary Heart Disease: A Meta-Analysis of Randomized Controlled Trials.Wan, Y., Wu, X., Kou, Y.[2020]
Text messaging interventions have been shown to effectively improve adherence to antiretroviral therapy and increase appointment attendance among people living with HIV, based on a systematic review of nine high-quality reviews involving 37 studies across 19 countries.
There are significant knowledge gaps regarding long-term outcomes and patient satisfaction with text messaging interventions, indicating a need for further research to fully understand their impact and potential in managing other chronic diseases.
Mobile phone text messaging interventions for HIV and other chronic diseases: an overview of systematic reviews and framework for evidence transfer.Mbuagbaw, L., Mursleen, S., Lytvyn, L., et al.[2022]
A review of 51 studies highlighted the importance of developing SMS content for mHealth initiatives aimed at supporting HIV/AIDS treatment adherence, emphasizing the need for formative research and grounding messages in behavior change theory.
Best practices for creating effective SMS messages include consulting with experts and using established behavior change frameworks to enhance the effectiveness of mobile health interventions in resource-limited settings.
Content guidance for mobile phones short message service (SMS)-based antiretroviral therapy adherence and appointment reminders: a review of the literature.Kerrigan, A., Kaonga, NN., Tang, AM., et al.[2023]

References

The Impact of Text Message On Self-Management for Coronary Heart Disease: A Meta-Analysis of Randomized Controlled Trials. [2020]
Mobile phone text messaging interventions for HIV and other chronic diseases: an overview of systematic reviews and framework for evidence transfer. [2022]
Content guidance for mobile phones short message service (SMS)-based antiretroviral therapy adherence and appointment reminders: a review of the literature. [2023]
The Impact of a Maternal Education Program Through Text Messaging in Rural China: Cluster Randomized Controlled Trial. [2020]
Impact of an Educational Text Message Intervention on Adolescents' Knowledge and High-Risk Behaviors. [2018]
Text messages as a learning tool for midwives. [2022]
Cell phone-based health education messaging improves health literacy. [2018]
Co-design and implementation of a mHealth intervention targeting fathers and mothers to improve breastfeeding. [2023]
Text4baby: development and implementation of a national text messaging health information service. [2021]
Text Message Analysis Using Machine Learning to Assess Predictors of Engagement With Mobile Health Chronic Disease Prevention Programs: Content Analysis. [2022]
11.United Statespubmed.ncbi.nlm.nih.gov
Patient and health-care worker experiences of an HIV viral load intervention using SMS: A qualitative study. [2020]